Identifying and quantifying proteolytic events and the natural N terminome by terminal amine isotopic labeling of substrates (Q34220314)

31 July 2017

Identifying and quantifying proteolytic events and the natural N terminome by terminal amine isotopic labeling of substrates (English)

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31 July 2017

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Ulrich auf dem Keller

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object named as

Ulrich auf dem Keller

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Christopher Overall

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object named as

Christopher M Overall

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Jayachandran N Kizhakkedathu

31 July 2017

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object named as

Jayachandran N Kizhakkedathu

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31 July 2017

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Magda Gioia

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31 July 2017

Oded Kleifeld

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31 July 2017

Alain Doucet

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31 July 2017

Anna Prudova

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22 September 2011

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1578-1611

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https://scigraph.springernature.com/pub.10.1038/nprot.2011.382

31 July 2017

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Multiplex N-terminome analysis of MMP-2 and MMP-9 substrate degradomes by iTRAQ-TAILS quantitative proteomics

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A statistics-based platform for quantitative N-terminome analysis and identification of protease cleavage products

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Proteolytic processing of SDF-1alpha reveals a change in receptor specificity mediating HIV-associated neurodegeneration

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Molecular determinants of metalloproteinase substrate specificity: matrix metalloproteinase substrate binding domains, modules, and exosites

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Impact of the N-terminal amino acid on targeted protein degradation

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Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides

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Positional proteomics: selective recovery and analysis of N-terminal proteolytic peptides

31 March 2020

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Isolation of N-terminal protein sequence tags from cyanogen bromide cleaved proteins as a novel approach to investigate hydrophobic proteins

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Positional proteomics: preparation of amino-terminal peptides as a strategy for proteome simplification and characterization

31 March 2020

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Global sequencing of proteolytic cleavage sites in apoptosis by specific labeling of protein N termini

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Protein alpha-N-acetylation studied by N-terminomics

31 March 2020

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In search of partners: linking extracellular proteases to substrates

31 March 2020

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Metadegradomics: toward in vivo quantitative degradomics of proteolytic post-translational modifications of the cancer proteome.

31 March 2020

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Nalpha -terminal acetylation of eukaryotic proteins

31 March 2020

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31 March 2020

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31 March 2020

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Protease degradomics: a new challenge for proteomics

31 March 2020

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Differential dimethyl labeling of N-termini of peptides after guanidination for proteome analysis

31 March 2020

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Targeted analysis of protein termini.

31 March 2020

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Proteomic discovery of protease substrates

31 March 2020

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Profiling constitutive proteolytic events in vivo

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Identification of proteolytic cleavage sites by quantitative proteomics

31 March 2020

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A proteomic approach for the identification of cell-surface proteins shed by metalloproteases

31 March 2020

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Global mapping of the topography and magnitude of proteolytic events in apoptosis

31 March 2020

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Improved recovery of proteome-informative, protein N-terminal peptides by combined fractional diagonal chromatography (COFRADIC).

31 March 2020

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Caspase-specific and nonspecific in vivo protein processing during Fas-induced apoptosis.

31 March 2020

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Analysis of protein processing by N-terminal proteomics reveals novel species-specific substrate determinants of granzyme B orthologs

31 March 2020

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Proteome-wide Identification of HtrA2/Omi Substrates

31 March 2020

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In vivo chemical modification of proteins (post-translational modification).

31 March 2020

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Proteomics discovery of metalloproteinase substrates in the cellular context by iTRAQ labeling reveals a diverse MMP-2 substrate degradome.

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Identification of candidate angiogenic inhibitors processed by matrix metalloproteinase 2 (MMP-2) in cell-based proteomic screens: disruption of vascular endothelial growth factor (VEGF)/heparin affin regulatory peptide (pleiotrophin) and VEGF/Conne

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Pharmacoproteomics of a metalloproteinase hydroxamate inhibitor in breast cancer cells: dynamics of membrane type 1 matrix metalloproteinase-mediated membrane protein shedding

31 March 2020

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Stable-isotope dimethyl labeling for quantitative proteomics

31 March 2020

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Identification of formaldehyde-induced modifications in proteins: reactions with model peptides

31 March 2020

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Multiplex peptide stable isotope dimethyl labeling for quantitative proteomics.

31 March 2020

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Peptide labeling with isobaric tags yields higher identification rates using iTRAQ 4-plex compared to TMT 6-plex and iTRAQ 8-plex on LTQ Orbitrap

31 March 2020

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Characterization of protein phosphorylation by mass spectrometry using immobilized metal ion affinity chromatography with on-resin beta-elimination and Michael addition

31 March 2020

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https://api.crossref.org/works/10.1038%2FNPROT.2011.382

Temporal profiling of the adipocyte proteome during differentiation using a five-plex SILAC based strategy.

31 March 2020

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Cell-based identification of natural substrates and cleavage sites for extracellular proteases by SILAC proteomics.

31 March 2020

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PepC: proteomics software for identifying differentially expressed proteins based on spectral counting

31 March 2020

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Absolute protein expression profiling estimates the relative contributions of transcriptional and translational regulation.

31 March 2020

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Proteome-derived, database-searchable peptide libraries for identifying protease cleavage sites

31 March 2020

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Minimizing resolution of isotopically coded peptides in comparative proteomics

31 March 2020

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Stable-isotope dimethylation labeling combined with LC-ESI MS for quantification of amine-containing metabolites in biological samples

31 March 2020

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A predictive model for identifying proteins by a single peptide match.

31 March 2020

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A uniform proteomics MS/MS analysis platform utilizing open XML file formats

31 March 2020

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Probability-based protein identification by searching sequence databases using mass spectrometry data

31 March 2020

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TANDEM: matching proteins with tandem mass spectra

31 March 2020

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Comparative evaluation of mass spectrometry platforms used in large-scale proteomics investigations

31 March 2020

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Improving sensitivity by probabilistically combining results from multiple MS/MS search methodologies.

31 March 2020

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iProphet: multi-level integrative analysis of shotgun proteomic data improves peptide and protein identification rates and error estimates

31 March 2020

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Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry

31 March 2020

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Semisupervised model-based validation of peptide identifications in mass spectrometry-based proteomics.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNPROT.2011.382

Proteomic identification of multitasking proteins in unexpected locations complicates drug targeting

31 March 2020

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Updated biological roles for matrix metalloproteinases and new "intracellular" substrates revealed by degradomics

31 March 2020

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https://api.crossref.org/works/10.1038%2FNPROT.2011.382

TopFIND, a knowledgebase linking protein termini with function.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNPROT.2011.382

Silver staining of proteins in polyacrylamide gels

31 March 2020

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https://api.crossref.org/works/10.1038%2FNPROT.2011.382

Stop and go extraction tips for matrix-assisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.382

Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.382

Overalkylation of a protein digest with iodoacetamide.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.382

Iodoacetamide-induced artifact mimics ubiquitination in mass spectrometry

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.382

Reductive methylation of proteins with sodium cyanoborohydride. Identification, suppression and possible uses of N-cyanomethyl by-products

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.382

Direct cancer tissue proteomics: a method to identify candidate cancer biomarkers from formalin-fixed paraffin-embedded archival tissues

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.382

De novo sequencing of neuropeptides using reductive isotopic methylation and investigation of ESI QTOF MS/MS fragmentation pattern of neuropeptides with N-terminal dimethylation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.382

Adaptive discriminant function analysis and reranking of MS/MS database search results for improved peptide identification in shotgun proteomics

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.382

In-gel digestion for mass spectrometric characterization of proteins and proteomes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.382

A practical recipe for stable isotope labeling by amino acids in cell culture (SILAC)

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.382

Modular stop and go extraction tips with stacked disks for parallel and multidimensional Peptide fractionation in proteomics

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.382

Labeling of proteins by reductive methylation using sodium cyanoborohydride

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21959240

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NPROT.2011.382

1 reference

Dimensions Publication ID

31 July 2017

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