Enzyme-controlled nitrogen-atom transfer enables regiodivergent C-H amination (Q34489542)

2 August 2017

Enzyme-controlled nitrogen-atom transfer enables regiodivergent C-H amination (English)

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2 August 2017

5

Frances H Arnold

1 reference

2 August 2017

Todd K Hyster

1

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2 August 2017

Christopher C Farwell

series ordinal

2

1 reference

2 August 2017

Andrew R Buller

series ordinal

3

1 reference

2 August 2017

John A McIntosh

series ordinal

4

1 reference

2 August 2017

language of work or name

English

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publication date

24 October 2014

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2 August 2017

4

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Journal of the American Chemical Society

inferred from page(s)

published in

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2 August 2017

136

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2 August 2017

44

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2 August 2017

15505-15508

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Non-natural olefin cyclopropanation catalyzed by diverse cytochrome P450s and other hemoproteins

2 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

Structural, functional, and spectroscopic characterization of the substrate scope of the novel nitrating cytochrome P450 TxtE.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

Enantioselective imidation of sulfides via enzyme-catalyzed intermolecular nitrogen-atom transfer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

Intramolecular C(sp(3))H amination of arylsulfonyl azides with engineered and artificial myoglobin-based catalysts.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

Enhancing the efficiency and regioselectivity of P450 oxidation catalysts by unnatural amino acid mutagenesis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

Expanding P450 catalytic reaction space through evolution and engineering

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

P450-catalyzed intramolecular sp(3) C-H amination with arylsulfonyl azide substrates.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

Cytochrome P450-Catalyzed Insertion of Carbenoids into N-H Bonds

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

Direct nitration and azidation of aliphatic carbons by an iron-dependent halogenase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

Discovery of potent parthenolide-based antileukemic agents enabled by late-stage P450-mediated C-H functionalization

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

A serine-substituted P450 catalyzes highly efficient carbene transfer to olefins in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

Priming ammonia lyases and aminomutases for industrial and therapeutic applications.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

Olefin Cyclopropanation via Carbene Transfer Catalyzed by Engineered Cytochrome P450 Enzymes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

Controlled oxidation of remote sp3 C-H bonds in artemisinin via P450 catalysts with fine-tuned regio- and stereoselectivity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

Cytochrome P450–catalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

Metal-catalyzed nitrogen-atom transfer methods for the oxidation of aliphatic C-H bonds

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

Iron-catalyzed intramolecular allylic C-H amination.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

P450(BM3) (CYP102A1): connecting the dots.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

The medicinal chemist's toolbox: an analysis of reactions used in the pursuit of drug candidates.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

Ammonia lyases and aminomutases as biocatalysts for the synthesis of α-amino and β-amino acids

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

Combinatorial alanine substitution enables rapid optimization of cytochrome P450BM3 for selective hydroxylation of large substrates

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

Enzymatic functionalization of carbon-hydrogen bonds

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

Cytochrome P450 compound I: capture, characterization, and C-H bond activation kinetics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

Hydrocarbon hydroxylation by cytochrome P450 enzymes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

Catalytic C–H functionalization by metal carbenoid and nitrenoid insertion

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

Analysis of the reactions used for the preparation of drug candidate molecules

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

The catalytic pathway of cytochrome p450cam at atomic resolution

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

C-H bond functionalization: An aminated reaction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

Regioselective o-hydroxylation of monosubstituted benzenes by P450 BM3.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

Scanning chimeragenesis: the approach used to change the substrate selectivity of fatty acid monooxygenase CYP102A1 to that of terpene omega-hydroxylase CYP4C7.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

Regio- and enantioselective alkane hydroxylation with engineered cytochromes P450 BM-3.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

Selective Intramolecular CH Amination through the Metalloradical Activation of Azides: Synthesis of 1,3-Diamines under Neutral and Nonoxidative Conditions

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

NR Transfer Reactivity of Azo-Compound I of P450. How Does the Nitrogen Substituent Tune the Reactivity of the Species toward CH and CC Activation?

9 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227740

Enantioselective catalytic aziridinations and asymmetric nitrene insertions into CH bonds

9 December 2018

1 reference

12 December 2020

Direct Spectroscopic Characterization of a Transitory Dirhodium Donor-Acceptor Carbene Complex

1 reference

12 December 2020

Enantioselective intramolecular benzylic C-H bond amination: efficient synthesis of optically active benzosultams

1 reference

12 December 2020

Copper-nitrene complexes in catalytic C-H amination

1 reference

12 December 2020

Cobalt-catalyzed intramolecular C-H amination with arylsulfonyl azides

1 reference

12 December 2020

Rh-catalyzed amination of ethereal Calpha-H bonds: a versatile strategy for the synthesis of complex amines

1 reference

12 December 2020

P450 fingerprinting method for rapid discovery of terpene hydroxylating P450 catalysts with diversified regioselectivity

1 reference

12 December 2020

Improved Cyclopropanation Activity of Histidine-Ligated Cytochrome P450 Enables the Enantioselective Formal Synthesis of Levomilnacipran

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1021/JA509308V

Enantioselective intramolecular C-H amination catalyzed by engineered cytochrome P450 enzymes in vitro and in vivo

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1021/JA509308V

Tuning P450 Enzymes as Oxidation Catalysts

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1021/JA509308V

Identifiers

DOI

10.1021/JA509308V

1 reference

2 August 2017

1 reference

2 August 2017

1 reference