Expanding P450 catalytic reaction space through evolution and engineering (Q26997321)

Crossref

Christopher C Farwell

series ordinal

2

1 reference

Crossref

language of work or name

1 reference

April 2014

1 reference

Current Opinion in Chemical Biology

published in

1 reference

volume

19

1 reference

page(s)

126-34

1 reference

Cell-free biology: exploiting the interface between synthetic biology and synthetic chemistry

cites work

1 reference

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Unusual mechanism of hydrocarbon formation in the housefly: cytochrome P450 converts aldehyde to the sex pheromone component (Z)-9-tricosene and CO2

21 March 2017

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Precision is essential for efficient catalysis in an evolved Kemp eliminase

21 March 2017

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A serine-substituted P450 catalyzes highly efficient carbene transfer to olefins in vivo

21 March 2017

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What makes a protein fold amenable to functional innovation? Fold polarity and stability trade-offs

21 March 2017

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Investigation of the substrate range of CYP199A4: modification of the partition between hydroxylation and desaturation activities by substrate and protein engineering

21 March 2017

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Crystal structure of a phenol-coupling P450 monooxygenase involved in teicoplanin biosynthesis

21 March 2017

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Structural fine-tuning of a multifunctional cytochrome P450 monooxygenase

21 March 2017

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Structural characterization of CYP165D3, a cytochrome P450 involved in phenolic coupling in teicoplanin biosynthesis

21 March 2017

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Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction

21 March 2017

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An insect-specific P450 oxidative decarbonylase for cuticular hydrocarbon biosynthesis

21 March 2017

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Terminal olefin (1-alkene) biosynthesis by a novel p450 fatty acid decarboxylase from Jeotgalicoccus species

21 March 2017

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Olefin Cyclopropanation via Carbene Transfer Catalyzed by Engineered Cytochrome P450 Enzymes

21 March 2017

1 reference

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The Fe(III)(H2O2) Complex as a Highly Efficient Oxidant in Sulfoxidation Reactions: Revival of an Underrated Oxidant in Cytochrome P450.

7 April 2017

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Cytochrome P450-Catalyzed Insertion of Carbenoids into N-H Bonds

28 September 2017

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Enantioselective intramolecular C-H amination catalyzed by engineered cytochrome P450 enzymes in vitro and in vivo

28 September 2017

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Reactive intermediates in cytochrome p450 catalysis

28 September 2017

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Unusual cytochrome p450 enzymes and reactions

28 September 2017

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Differential hydrogen bonding in human CYP17 dictates hydroxylation versus lyase chemistry

28 September 2017

1 reference

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On the development of new biocatalytic processes for practical pharmaceutical synthesis

28 September 2017

1 reference

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Cytochrome P450–catalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis

28 September 2017

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Diversity of P450 enzymes in the biosynthesis of natural products

28 September 2017

1 reference

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P450(BM3) (CYP102A1): connecting the dots.

28 September 2017

1 reference

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Enzymatic functionalization of carbon-hydrogen bonds

28 September 2017

1 reference

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Enzyme (re)design: lessons from natural evolution and computation

28 September 2017

1 reference

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Evolution of enzyme superfamilies

28 September 2017

1 reference

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Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity

28 September 2017

1 reference

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Geraniol hydroxylase and hydroxygeraniol oxidase activities of the CYP76 family of cytochrome P450 enzymes and potential for engineering the early steps of the (seco)iridoid pathway

28 September 2017

1 reference

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Pyran formation by an atypical CYP-mediated four-electron oxygenation-cyclization cascade in an engineered aureothin pathway

31 May 2018

1 reference

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Carboxyl formation from methyl via triple hydroxylations by XiaM in xiamycin A biosynthesis.

31 May 2018

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Convergent Asymmetric Synthesis of (+)-Aureothin Employing an Oxygenase-Mediated Resolution Step

28 November 2018

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C-H bond activation in heme proteins: the role of thiolate ligation in cytochrome P450.

28 November 2018

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Catalytic promiscuity of halohydrin dehalogenase and its application in enantioselective epoxide ring opening

28 November 2018

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Stereospecific alkyne reduction: novel activity of old yellow enzymes.

28 November 2018

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Subtilisin-catalyzed resolution of N-acyl arylsulfinamides.

28 November 2018

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Formation of the aureothin tetrahydrofuran ring by a bifunctional cytochrome p450 monooxygenase

28 November 2018

1 reference

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Epoxidation of olefins by hydroperoxo-ferric cytochrome P450.

28 November 2018

1 reference

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Which oxidant is really responsible for sulfur oxidation by cytochrome P450?

28 November 2018

1 reference

12 December 2020

Is the ferric hydroperoxy species responsible for sulfur oxidation in cytochrome p450s?

1 reference

12 December 2020

Substituent effects on the phenol coupling reaction catalyzed by the vancomycin biosynthetic P450 enzyme OxyB

1 reference

12 December 2020

Cobalt-catalyzed intramolecular C-H amination with arylsulfonyl azides

1 reference

12 December 2020

Synthesis: A constructive debate

1 reference

12 December 2020