Mechanisms of signaling by the hematopoietic-specific adaptor proteins, SLP-76 and LAT and their B cell counterpart, BLNK/SLP-65. (Q34419552)

2 August 2017

1 reference

title

Mechanisms of signaling by the hematopoietic-specific adaptor proteins, SLP-76 and LAT and their B cell counterpart, BLNK/SLP-65. (English)

1 reference

2 August 2017

Yablonski D

1

1 reference

PubMed ID

11680012

2 August 2017

Weiss A

series ordinal

2

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2 August 2017

1 January 2001

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2 August 2017

Advances in Immunology

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2 August 2017

79

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2 August 2017

93-128

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Allelic exclusion of the T cell receptor beta locus requires the SH2 domain-containing leukocyte protein (SLP)-76 adaptor protein

2 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Grf40, A novel Grb2 family member, is involved in T cell signaling through interaction with SLP-76 and LAT

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

SLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Recruitment of SLP-76 to the membrane and glycolipid-enriched membrane microdomains replaces the requirement for linker for activation of T cells in T cell receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Mona, a novel hematopoietic-specific adaptor interacting with the macrophage colony-stimulating factor receptor, is implicated in monocyte/macrophage development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Clnk, a novel SLP-76-related adaptor molecule expressed in cytokine-stimulated hemopoietic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Phospholipase C-gamma as a signal-transducing element

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Fetal hemorrhage and platelet dysfunction in SLP-76-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Functional independence and interdependence of the Src homology domains of phospholipase C-gamma1 in B-cell receptor signal transduction.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

GRID: a novel Grb-2-related adapter protein that interacts with the activated T cell costimulatory receptor CD28

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Linker for activation of T cells (LAT), a novel immunohistochemical marker for T cells, NK cells, mast cells, and megakaryocytes: evaluation in normal and pathological conditions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

SLP-76 and Vav function in separate, but overlapping pathways to augment interleukin-2 promoter activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Xid-like phenotypes: a B cell signalosome takes shape

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

BLNK: a central linker protein in B cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Multiple p21ras effector pathways regulate nuclear factor of activated T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

The p85 Subunit of Phosphatidylinositol 3-Kinase Associates with the Fc Receptor γ-Chain and Linker for Activitor of T Cells (LAT) in Platelets Stimulated by Collagen and Convulxin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

A BASH/SLP-76-related adaptor protein MIST/Clnk involved in IgE receptor-mediated mast cell degranulation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Tyrosine phosphorylation of SLP-76 is downstream of Syk following stimulation of the collagen receptor in platelets

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Lck regulates Vav activation of members of the Rho family of GTPases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Involvement of guanosine triphosphatases and phospholipase C-gamma2 in extracellular signal-regulated kinase, c-Jun NH2-terminal kinase, and p38 mitogen-activated protein kinase activation by the B cell antigen receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

SLP-76 is a substrate of the high affinity IgE receptor-stimulated protein tyrosine kinases in rat basophilic leukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Pleiotropic contributions of phospholipase C-gamma1 (PLC-gamma1) to T-cell antigen receptor-mediated signaling: reconstitution studies of a PLC-gamma1-deficient Jurkat T-cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

BLNK required for coupling Syk to PLC gamma 2 and Rac1-JNK in B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Involvement of LAT, Gads, and Grb2 in compartmentation of SLP-76 to the plasma membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Abnormal development and function of B lymphocytes in mice deficient for the signaling adaptor protein SLP-65

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Small splenic B cells that bind to antigen-specific T helper (Th) cells and face the site of cytokine production in the Th cells selectively proliferate: immunofluorescence microscopic studies of Th-B antigen-presenting cell interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Localization of LAT in glycolipid-enriched microdomains is required for T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

HPK1 is activated by lymphocyte antigen receptors and negatively regulates AP-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Gads is a novel SH2 and SH3 domain-containing adaptor protein that binds to tyrosine-phosphorylated Shc

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

The hematopoietic-specific adaptor protein gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Identification of an atypical Grb2 carboxyl-terminal SH3 domain binding site in Gab docking proteins reveals Grb2-dependent and -independent recruitment of Gab1 to receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

An essential role for BLNK in human B cell development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Tyrosine phosphorylation of Grb2-associated proteins correlates with phospholipase C gamma 1 activation in T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Implication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor-mediated interleukin 2 production

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Molecular cloning of SLAP-130, an SLP-76-associated substrate of the T cell antigen receptor-stimulated protein tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

T cell antigen receptor-mediated activation of phospholipase C requires tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

In vitro and in vivo macrophage function can occur independently of SLP-76

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Requirement for B cell linker protein (BLNK) in B cell development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

LAT is required for tyrosine phosphorylation of phospholipase cgamma2 and platelet activation by the collagen receptor GPVI.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

NK cytokine secretion and cytotoxicity occur independently of the SLP-76 adaptor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

T cell antigen receptor signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Molecular cloning and expression of human grap-2, a novel leukocyte-specific SH2- and SH3-containing adaptor-like protein that binds to gab-1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

A role for Bruton's tyrosine kinase (Btk) in platelet activation by collagen.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCR zeta/CD3 induction of interleukin-2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

FYN-T-FYB-SLP-76 interactions define a T-cell receptor zeta/CD3-mediated tyrosine phosphorylation pathway that up-regulates interleukin 2 transcription in T-cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Transcription factors of the NFAT family: regulation and function

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

LAT is essential for Fc(epsilon)RI-mediated mast cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Resting lymphocyte kinase (Rlk/Txk) targets lymphoid adaptor SLP-76 in the cooperative activation of interleukin-2 transcription in T-cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Cytoskeletal rearrangement during migration and activation of T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Itk/Emt/Tsk activation in response to CD3 cross-linking in Jurkat T cells requires ZAP-70 and Lat and is independent of membrane recruitment

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

GRB2 and phospholipase C-gamma 1 associate with a 36- to 38-kilodalton phosphotyrosine protein after T-cell receptor stimulation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

SH2 domains recognize specific phosphopeptide sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

JNK is involved in signal integration during costimulation of T lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Interaction of SLP adaptors with the SH2 domain of Tec family kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Requirement of phospholipase C-gamma 2 activation in surface immunoglobulin M-induced B cell apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

p95vav associates with tyrosine-phosphorylated SLP-76 in antigen-stimulated T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Rac-1 regulates nuclear factor of activated T cells (NFAT) C1 nuclear translocation in response to Fcepsilon receptor type 1 stimulation of mast cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Killer cell inhibitory receptor recognition of human leukocyte antigen (HLA) class I blocks formation of a pp36/PLC-gamma signaling complex in human natural killer (NK) cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

T cell antigen-receptor signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

T cell receptor-mediated signs and signals governing T cell development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Novel isoform of lymphoid adaptor FYN-T-binding protein (FYB-130) interacts with SLP-76 and up-regulates interleukin 2 production

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Phospholipase Cgamma2 is essential in the functions of B cell and several Fc receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Collagen receptor signalling in platelets: extending the role of the ITAM.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Molecular cloning of the cDNA encoding pp36, a tyrosine-phosphorylated adaptor protein selectively expressed by T cells and natural killer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

SLP-65: a new signaling component in B lymphocytes which requires expression of the antigen receptor for phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Functional complementation of BLNK by SLP-76 and LAT linker proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

p21ras and calcineurin synergize to regulate the nuclear factor of activated T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Association of Nck with tyrosine-phosphorylated SLP-76 in activated T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Membrane compartmentation is required for efficient T cell activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

B cell development and activation defects resulting in xid-like immunodeficiency in BLNK/SLP-65-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

A Nck-Pak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNK

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Identification of a phospholipase C-gamma1 (PLC-gamma1) SH3 domain-binding site in SLP-76 required for T-cell receptor-mediated activation of PLC-gamma1 and NFAT

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Cbl suppresses B cell receptor-mediated phospholipase C (PLC)-gamma2 activation by regulating B cell linker protein-PLC-gamma2 binding

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Essential role of LAT in T cell development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2801%2979003-7

7 January 2021

10.1016/S0065-2776(01)79003-7

Identifiers

DOI

1 reference

2 August 2017

1 reference

PubMed ID

11680012