Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76 (Q28647329)

2

1 reference

3 February 2017

J. Y. Bu

3

1 reference

3 February 2017

B. Mayer

4

1 reference

3 February 2017

J. Chernoff

5

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3 February 2017

D. Straus

6

1 reference

3 February 2017

A. C. Chan

Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott-Aldrich syndrome

7

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3 February 2017

language of work or name

English

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publication date

1 November 1998

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3 February 2017

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3 February 2017

9

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3 February 2017

5

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3 February 2017

607–616

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3 February 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Interaction of the Nck adapter protein with p21-activated kinase (PAK1)

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

T cell antigen receptor signal transduction pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Regulation of antigen receptor signal transduction by protein tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

A Novel Ligand for SH3 Domains

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

The SH2- and SH3-containing Nck protein transforms mammalian fibroblasts in the absence of elevated phosphotyrosine levels

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Cloning and characterization of a human protein kinase with homology to Ste20

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Isolation of a novel gene mutated in Wiskott-Aldrich syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Rac GTPase interacts with GAPs and target proteins through multiple effector sites.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Drosophila photoreceptor axon guidance and targeting requires the dreadlocks SH2/SH3 adapter protein.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

A Drosophila homolog of the Rac- and Cdc42-activated serine/threonine kinase PAK is a potential focal adhesion and focal complex protein that colocalizes with dynamic actin structures

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Binding of NCK to SOS and activation of ras-dependent gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Distinct tyrosine phosphorylation sites in ZAP-70 mediate activation and negative regulation of antigen receptor function

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Nck associates with the SH2 domain-docking protein IRS-1 in insulin-stimulated cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Nck, a melanoma cDNA encoding a cytoplasmic protein consisting of the src homology units SH2 and SH3

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

The SH2 and SH3 domain-containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Cytoskeletal polarization of T cells is regulated by an immunoreceptor tyrosine-based activation motif-dependent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

The SH2/SH3 domain-containing protein Nck is recognized by certain anti-phospholipase C-gamma 1 monoclonal antibodies, and its phosphorylation on tyrosine is stimulated by platelet-derived growth factor and epidermal growth factor treatment

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Phospholipase C-gamma is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Implication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor-mediated interleukin 2 production

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Differential regulation of activation-induced tyrosine phosphorylation and recruitment of SLP-76 to Vav by distinct isoforms of the CD45 protein-tyrosine phosphatase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Phosphorylation of Nck in response to a variety of receptors, phorbol myristate acetate, and cyclic AMP

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Isolation of a NCK-associated kinase, PRK2, an SH3-binding protein and potential effector of Rho protein signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCR zeta/CD3 induction of interleukin-2

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Activation of Ras and other signaling pathways by receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

p95vav associates with tyrosine-phosphorylated SLP-76 in antigen-stimulated T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Complex complexes: signaling at the TCR.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Genetic evidence of a role for Lck in T-cell receptor function independent or downstream of ZAP-70/Syk protein tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

A functional T-cell receptor signaling pathway is required for p95vav activity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

A conserved negative regulatory region in alphaPAK: inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980658-5

7 January 2021

10.1016/S1074-7613(00)80658-5

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

4718058

4718058

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference