FYN-T-FYB-SLP-76 interactions define a T-cell receptor zeta/CD3-mediated tyrosine phosphorylation pathway that up-regulates interleukin 2 transcription in T-cells (Q22010396)

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English	FYN-T-FYB-SLP-76 interactions define a T-cell receptor zeta/CD3-mediated tyrosine phosphorylation pathway that up-regulates interleukin 2 transcription in T-cells	scientific article

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FYN-T-FYB-SLP-76 interactions define a T-cell receptor zeta/CD3-mediated tyrosine phosphorylation pathway that up-regulates interleukin 2 transcription in T-cells (English)

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phosphorylation

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based on heuristic

inferred from title

author name string

M Raab

1

author given names

M

author last names

Raab

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7 February 2023

H Kang

2

author given names

H

author last names

Kang

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7 February 2023

A da Silva

3

author given names

A

author last names

da Silva

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7 February 2023

X Zhu

4

author given names

X

author last names

Zhu

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7 February 2023

C E Rudd

5

author given names

C E

author last names

Rudd

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7 February 2023

language of work or name

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publication date

23 July 1999

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Journal of Biological Chemistry

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274

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30

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21170-9

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Two-step TCR zeta/CD3-CD4 and CD28 signaling in T cells: SH2/SH3 domains, protein-tyrosine and lipid kinases

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https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Signal transduction by lymphocyte antigen receptors

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https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

T cell antigen receptor signaling: three families of tyrosine kinases and a phosphatase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Complex complexes: signaling at the TCR.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases

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https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Activating and inhibitory mutations in adjacent tyrosines in the kinase domain of ZAP-70.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

p56lck interacts via its src homology 2 domain with the ZAP-70 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Genetic evidence for differential coupling of Syk family kinases to the T-cell receptor: reconstitution studies in a ZAP-70-deficient Jurkat T-cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Adaptor proteins in lymphocyte antigen-receptor signaling.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Molecular cloning of the cDNA encoding pp36, a tyrosine-phosphorylated adaptor protein selectively expressed by T cells and natural killer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

alpha, beta, gamma, and delta T cell antigen receptor genes arose early in vertebrate phylogeny.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Differential regulation of activation-induced tyrosine phosphorylation and recruitment of SLP-76 to Vav by distinct isoforms of the CD45 protein-tyrosine phosphatase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Implication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor-mediated interleukin 2 production

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Product of vav proto-oncogene defines a new class of tyrosine protein kinase substrates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Molecular cloning of SLAP-130, an SLP-76-associated substrate of the T cell antigen receptor-stimulated protein tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Multiple features of the p59fyn src homology 4 domain define a motif for immune-receptor tyrosine-based activation motif (ITAM) binding and for plasma membrane localization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

alpha beta T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

T cell receptor zeta/CD3-p59fyn(T)-associated p120/130 binds to the SH2 domain of p59fyn(T)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

SH2 domains recognize specific phosphopeptide sequences

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Different domains of the AP-1 adaptor complex are required for Golgi membrane binding and clathrin recruitment

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Tyrosine phosphorylation of Pyk2 is selectively regulated by Fyn during TCR signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Distinct intracellular localization of Lck and Fyn protein tyrosine kinases in human T lymphocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Regulation of ZAP-70 intracellular localization: visualization with the green fluorescent protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Engagement of the TcR/CD3 complex stimulates p59fyn(T) activity: detection of associated proteins at 72 and 120-130 kD.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Gene transfer investigations of p56-LCK function in IL-2-dependent T-cell lines: implications for mechanisms of IL-2-signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Activated lck tyrosine protein kinase stimulates antigen-independent interleukin-2 production in T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Unique catalytic properties dictate the enhanced function of p59fynT, the hemopoietic cell-specific isoform of the Fyn tyrosine protein kinase, in T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Differential association of protein tyrosine kinases with the T cell receptor is linked to the induction of anergy and its prevention by B7 family-mediated costimulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Hematopoietic cell phosphatase (HCP) regulates p56LCK phosphorylation and ZAP-70 binding to T cell receptor zeta chain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

From TCR Engagement to T Cell Activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

21 January 2018

pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

7 January 2021

based on heuristic

inferred from DOI database lookup

Fyn can partially substitute for Lck in T lymphocyte development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of the T cell antigen receptor--p60fyn protein tyrosine kinase association by chemical cross-linking

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

7 January 2021

based on heuristic

inferred from DOI database lookup

p59fyn tyrosine kinase associates with multiple T-cell receptor subunits through its unique amino-terminal domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.30.21170

7 January 2021

based on heuristic

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Identifiers

10.1074/JBC.274.30.21170

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