Caspase-1: the inflammasome and beyond (Q34344861)

1 August 2017

Caspase-1: the inflammasome and beyond (English)

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1 August 2017

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Gabriel Sollberger

1

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1 August 2017

Gerhard E Strittmatter

2

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1 August 2017

Martha Garstkiewicz

3

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1 August 2017

Jennifer Sand

4

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1 August 2017

Hans-Dietmar Beer

5

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1 August 2017

15 May 2013

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1 August 2017

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1 August 2017

20

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1 August 2017

2

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1 August 2017

115-125

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Programmed cell death: alive and well in the new millennium

1 August 2017

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https://api.crossref.org/works/10.1177%2F1753425913484374

Caspases in apoptosis and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Caspase-1-induced pyroptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Caspase-14 reveals its secrets

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Caspase-14 protects against epidermal UVB photodamage and water loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Inflammatory caspases and inflammasomes: master switches of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Confinement of caspase-12 proteolytic activity to autoprocessing

21 January 2018

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https://api.crossref.org/works/10.1177%2F1753425913484374

Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Identification of a monocyte specific pre-interleukin 1 beta convertase activity

21 January 2018

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https://api.crossref.org/works/10.1177%2F1753425913484374

A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

21 January 2018

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https://api.crossref.org/works/10.1177%2F1753425913484374

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

21 January 2018

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https://api.crossref.org/works/10.1177%2F1753425913484374

Pyroptosis: host cell death and inflammation

21 January 2018

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https://api.crossref.org/works/10.1177%2F1753425913484374

Inflammasomes in health and disease

21 January 2018

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https://api.crossref.org/works/10.1177%2F1753425913484374

Apoptosis and caspases in neurodegenerative diseases

21 January 2018

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https://api.crossref.org/works/10.1177%2F1753425913484374

NLRs at the intersection of cell death and immunity

21 January 2018

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https://api.crossref.org/works/10.1177%2F1753425913484374

Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme

21 January 2018

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https://api.crossref.org/works/10.1177%2F1753425913484374

Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Caspase 1-independent activation of interleukin-1beta in neutrophil-predominant inflammation

21 January 2018

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https://api.crossref.org/works/10.1177%2F1753425913484374

Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Neutrophil proteinase 3-mediated induction of bioactive IL-18 secretion by human oral epithelial cells

21 January 2018

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https://api.crossref.org/works/10.1177%2F1753425913484374

Interleukin-18 and the pathogenesis of inflammatory diseases

21 January 2018

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https://api.crossref.org/works/10.1177%2F1753425913484374

Caspase-1 promiscuity is counterbalanced by rapid inactivation of processed enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Targeted peptidecentric proteomics reveals caspase-7 as a substrate of the caspase-1 inflammasomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Inflammatory stimuli regulate caspase substrate profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock

21 January 2018

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https://api.crossref.org/works/10.1177%2F1753425913484374

Immunological and inflammatory functions of the interleukin-1 family

21 January 2018

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https://api.crossref.org/works/10.1177%2F1753425913484374

Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Granzyme B-dependent proteolysis acts as a switch to enhance the proinflammatory activity of IL-1α.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Mechanisms of regulated unconventional protein secretion

21 January 2018

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https://api.crossref.org/works/10.1177%2F1753425913484374

An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist

21 January 2018

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https://api.crossref.org/works/10.1177%2F1753425913484374

An autoinflammatory disease due to homozygous deletion of the IL1RN locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

NALPs: a novel protein family involved in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin

21 January 2018

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https://api.crossref.org/works/10.1177%2F1753425913484374

Anthrax toxin induces macrophage death by p38 MAPK inhibition but leads to inflammasome activation via ATP leakage

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Cutting edge: resistance to Bacillus anthracis infection mediated by a lethal toxin sensitive allele of Nalp1b/Nlrp1b.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

NALP1 in vitiligo-associated multiple autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Inflammasomes and their roles in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Detection of prokaryotic mRNA signifies microbial viability and promotes immunity

21 January 2018

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https://api.crossref.org/works/10.1177%2F1753425913484374

ER stress activates the NLRP3 inflammasome via an UPR-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

In vivo regulation of interleukin 1beta in patients with cryopyrin-associated periodic syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Inflammatory caspases in innate immunity and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Critical functions of priming and lysosomal damage for NLRP3 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Mitochondria: Sovereign of inflammation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

A role for mitochondria in NLRP3 inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

GBP5 promotes NLRP3 inflammasome assembly and immunity in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Novel role of PKR in inflammasome activation and HMGB1 release

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Phosphorylation of NLRC4 is critical for inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Innate immunity: cytoplasmic DNA sensing by the AIM2 inflammasome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Regulation of inflammasome signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Listeria monocytogenes triggers AIM2-mediated pyroptosis upon infrequent bacteriolysis in the macrophage cytosol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

IFI16 is an innate immune sensor for intracellular DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Inflammasomes in intestinal inflammation and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

IL-1 beta -converting enzyme (caspase-1) in intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Shigella flexneri induces apoptosis in infected macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Non-canonical inflammasome activation targets caspase-11

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Caspase-7 activation by the Nlrc4/Ipaf inflammasome restricts Legionella pneumophila infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Caspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin polymerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Manipulation of host cell death pathways during microbial infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Inflammasome-activated caspase 7 cleaves PARP1 to enhance the expression of a subset of NF-κB target genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Caspase-1 builds a new barrier to infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Inflammasome activators induce interleukin-1α secretion via distinct pathways with differential requirement for the protease function of caspase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Active caspase-1 is a regulator of unconventional protein secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Autophagy: a broad role in unconventional protein secretion?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Signal transduction by tumor necrosis factor and its relatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Caspase-1 activates nuclear factor of the kappa-enhancer in B cells independently of its enzymatic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

ASC directs NF-kappaB activation by regulating receptor interacting protein-2 (RIP2) caspase-1 interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Regulation of NF-κB signaling by caspases and MALT1 paracaspase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Interaction patches of procaspase-1 caspase recruitment domains (CARDs) are differently involved in procaspase-1 activation and receptor-interacting protein 2 (RIP2)-dependent nuclear factor κB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Naturally occurring genetic variants of human caspase-1 differ considerably in structure and the ability to activate interleukin-1β.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

NF-kappaB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

An NLRP7-containing inflammasome mediates recognition of microbial lipopeptides in human macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Deubiquitinases regulate the activity of caspase-1 and interleukin-1β secretion via assembly of the inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

Control of Intestinal Homeostasis, Colitis, and Colitis-Associated Colorectal Cancer by the Inflammatory Caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425913484374

21 January 2018

Identifiers

DOI

10.1177/1753425913484374

1 reference

1 August 2017

1 reference