Scriptaid, a novel histone deacetylase inhibitor, protects against traumatic brain injury via modulation of PTEN and AKT pathway : scriptaid protects against TBI via AKT. (Q34310319)

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English	Scriptaid, a novel histone deacetylase inhibitor, protects against traumatic brain injury via modulation of PTEN and AKT pathway : scriptaid protects against TBI via AKT.	scientific article

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17 February 2020

Scriptaid, a novel histone deacetylase inhibitor, protects against traumatic brain injury via modulation of PTEN and AKT pathway : scriptaid protects against TBI via AKT (English)

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17 February 2020

traumatic brain injury

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17 February 2020

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17 February 2020

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Jun Chen

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17 February 2020

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Xiaoyan Jiang

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17 February 2020

Hongjian Pu

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17 February 2020

Wenting Zhang

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17 February 2020

Chengrui An

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17 February 2020

Xiaoming Hu

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17 February 2020

Anthony Kian-Fong Liou

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17 February 2020

Yanqin Gao

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17 February 2020

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1 January 2013

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17 February 2020

Neurotherapeutics

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17 February 2020

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17 February 2020

1

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17 February 2020

124-142

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17 February 2020

https://scigraph.springernature.com/pub.10.1007/s13311-012-0157-2

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PTEN Tumor Suppressor Network in PI3K-Akt Pathway Control

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Free-radical scavenger edaravone treatment confers neuroprotection against traumatic brain injury in rats.

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Histone deacetylase inhibitors as therapeutic agents for acute central nervous system injuries

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Valproate administered after traumatic brain injury provides neuroprotection and improves cognitive function in rats

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6 July 2018

Blood-brain barrier breakdown as a therapeutic target in traumatic brain injury

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6 July 2018

Traumatic brain injury: a review of pathophysiology and management

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6 July 2018

Targeted deletion of NF-kappaB p50 diminishes the cardioprotection of histone deacetylase inhibition

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6 July 2018

Inhibition of histone deacetylase protects the retina from ischemic injury

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Histone deacetylase inhibitor valproic acid inhibits cancer cell proliferation via down-regulation of the alzheimer amyloid precursor protein

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Apurinic/apyrimidinic endonuclease APE1 is required for PACAP-induced neuroprotection against global cerebral ischemia

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Cell death mechanisms and modulation in traumatic brain injury

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Inhibitors of class 1 histone deacetylases reverse contextual memory deficits in a mouse model of Alzheimer's disease

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Long-term psychiatric outcomes following traumatic brain injury: a review of the literature

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6 July 2018

The new neuroscience frontier: promoting neuroplasticity and brain repair in traumatic brain injury

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6 July 2018

Histone deacetylase inhibitor ITF2357 is neuroprotective, improves functional recovery, and induces glial apoptosis following experimental traumatic brain injury

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6 July 2018

Histone deactylase inhibition combined with behavioral therapy enhances learning and memory following traumatic brain injury

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6 July 2018

Histone deacetylase inhibitors promote neurosteroid-mediated cell differentiation and enhance serotonin-stimulated brain-derived neurotrophic factor gene expression in rat C6 glioma cells

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Equal numbers of neuronal and nonneuronal cells make the human brain an isometrically scaled-up primate brain

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Multifunctional drug treatment in neurotrauma

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6 July 2018

The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice

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6 July 2018

Therapeutic application of histone deacetylase inhibitors for central nervous system disorders

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Moderate and severe traumatic brain injury in adults.

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6 July 2018

HDAC inhibitor increases histone H3 acetylation and reduces microglia inflammatory response following traumatic brain injury in rats

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New insights into PTEN.

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Rationale for the use of histone deacetylase inhibitors as a dual therapeutic modality in multiple sclerosis

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DNA methylation and histone acetylation work in concert to regulate memory formation and synaptic plasticity

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Inhibition of histone deacetylase activity induces developmental plasticity in oligodendrocyte precursor cells

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A brief review of traumatic brain injury rehabilitation

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Immunohistochemical analysis of histone H3 acetylation and methylation--evidence for altered epigenetic signaling following traumatic brain injury in immature rats

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6 July 2018

Morris water maze search strategy analysis in PDAPP mice before and after experimental traumatic brain injury

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6 July 2018

HATs and HDACs in neurodegeneration: a tale of disconcerted acetylation homeostasis.

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6 July 2018

Cooperative phosphorylation of the tumor suppressor phosphatase and tensin homologue (PTEN) by casein kinases and glycogen synthase kinase 3beta

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6 July 2018

Remodeling chromatin and stress resistance in the central nervous system: histone deacetylase inhibitors as novel and broadly effective neuroprotective agents.

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6 July 2018

Fluoro-Jade C results in ultra high resolution and contrast labeling of degenerating neurons

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6 July 2018

Chronic behavioral testing after focal ischemia in the mouse: functional recovery and the effects of gender

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6 July 2018

Critical loss of CBP/p300 histone acetylase activity by caspase-6 during neurodegeneration.

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6 July 2018

Phosphorylation of the PTEN tail acts as an inhibitory switch by preventing its recruitment into a protein complex

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6 July 2018

Enhanced neurogenesis in the rodent hippocampus following traumatic brain injury

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6 July 2018

Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration

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6 July 2018

Phosphorylation of microtubule-associated protein 2 (MAP2) and its relevance for the regulation of the neuronal cytoskeleton function.

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6 July 2018

Experimental animal models of traumatic brain injury: medical and biomechanical mechanism.

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21 January 2018

Neuroprotective effects of hyperbaric oxygen treatment on traumatic brain injury in the rat.

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21 January 2018

Valproate ameliorates the survival and the motor performance in a transgenic mouse model of Huntington's disease.

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21 January 2018

Biological therapies of autoimmune diseases

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21 January 2018

Critical role of calpain I in mitochondrial release of apoptosis-inducing factor in ischemic neuronal injury.

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Religion and spirituality: can it adversely affect mental health treatment?

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Cyclic AMP response element binding protein (CREB) and CREB binding protein (CBP) in global cerebral ischemia

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28 October 2018

Minocycline protects against myocardial ischemia and reperfusion injury by inhibiting high mobility group box 1 protein in rats

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28 October 2018

A novel histone deacetylase inhibitor, Scriptaid, induces growth inhibition, cell cycle arrest and apoptosis in human endometrial cancer and ovarian cancer cells

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28 October 2018

Pathophysiological changes after traumatic brain injury: comparison of two experimental animal models by means of MRI.

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28 October 2018

Evidence of apoptotic cell death after experimental traumatic brain injury in the rat.

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28 October 2018

Pathophysiology of traumatic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/23132328

12 December 2020

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WITHDRAWN: Sodium butyrate protects against myocardial ischemia and reperfusion injury by inhibiting high mobility group box 1 protein in rats

1 reference

3 January 2024

https://opencitations.net/index/api/v1/citations/10.1016/J.BIOPHA.2010.09.005

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10.1007/S13311-012-0157-2

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Europe PubMed Central

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17 February 2020

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Europe PubMed Central

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17 February 2020

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17 February 2020

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