Cutting edge: Evidence for a dynamically driven T cell signaling mechanism. (Q34275752)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22611242%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

Cutting edge: Evidence for a dynamically driven T cell signaling mechanism (English)

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1 February 2020

2

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1 February 2020

Brian G Pierce

7

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1 February 2020

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Brian M Baker

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1 February 2020

author name string

William F Hawse

1

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1 February 2020

Michelle V Joyce

3

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1 February 2020

Lance M Hellman

4

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1 February 2020

Moushumi Hossain

5

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1 February 2020

Veronica Ryan

6

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1 February 2020

Zhiping Weng

8

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language of work or name

English

0 references

publication date

18 May 2012

1 reference

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1 February 2020

published in

Journal of Immunology

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1 February 2020

volume

188

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1 February 2020

page(s)

5819-5823

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1 February 2020

issue

12

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Disparate Degrees of Hypervariable Loop Flexibility Control T-Cell Receptor Cross-Reactivity, Specificity, and Binding Mechanism

1 February 2020

cites work

1 reference

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TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms

6 July 2018

1 reference

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Dynamic allostery: linkers are not merely flexible

6 July 2018

1 reference

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DNA binding alters coactivator interaction surfaces of the intact VDR-RXR complex

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375328

Mechanisms for T cell receptor triggering

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375328

Distinctive CD3 heterodimeric ectodomain topologies maximize antigen-triggered activation of alpha beta T cell receptors

6 July 2018

1 reference

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Evidence for a functional sidedness to the alphabetaTCR.

6 July 2018

1 reference

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Hydrogen exchange mass spectrometry: what is it and what can it tell us?

6 July 2018

1 reference

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Global dynamics of proteins: bridging between structure and function

6 July 2018

1 reference

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The alphabeta T cell receptor is an anisotropic mechanosensor.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375328

Sending signals dynamically

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375328

Structure-based design of a T-cell receptor leads to nearly 100-fold improvement in binding affinity for pepMHC.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375328

Allosteric signaling in the biotin repressor occurs via local folding coupled to global dampening of protein dynamics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375328

Solution mapping of T cell receptor docking footprints on peptide-MHC.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375328

Conformational entropy in molecular recognition by proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375328

Comparative evaluation of tandem MS search algorithms using a target-decoy search strategy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375328

Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375328

Dynamically driven protein allostery.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375328

Structural changes involved in protein binding correlate with intrinsic motions of proteins in the unbound state

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375328

A simple physical model for binding energy hot spots in protein-protein complexes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375328

Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375328

Mechanisms and uses of hydrogen exchange

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375328

Dynamic activation of an allosteric regulatory protein.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375328

Antigen ligation triggers a conformational change within the constant domain of the alphabeta T cell receptor.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375328

The Paragon Algorithm, a next generation search engine that uses sequence temperature values and feature probabilities to identify peptides from tandem mass spectra.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375328

T cell receptor recognition via cooperative conformational plasticity.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375328

Anisotropic network model: systematic evaluation and a new web interface.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375328

Stable, soluble T-cell receptor molecules for crystallization and therapeutics

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375328

Two different T cell receptors use different thermodynamic strategies to recognize the same peptide/MHC ligand

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22611242

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cooperativity between T cell receptor complexes revealed by conformational mutants of CD3epsilon

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22611242

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4049/JIMMUNOL.1200952

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22611242%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22611242%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22611242%20AND%20SRC:MED&resulttype=core&format=json