Loss of protein tyrosine phosphatase N2 potentiates epidermal growth factor suppression of intestinal epithelial chloride secretion (Q34212116)

31 July 2017

Loss of protein tyrosine phosphatase N2 potentiates epidermal growth factor suppression of intestinal epithelial chloride secretion (English)

1 reference

31 July 2017

Michael Scharl

1

1 reference

PubMed ID

20689057

31 July 2017

Ivan Rudenko

series ordinal

2

1 reference

PubMed ID

20689057

31 July 2017

Declan F McCole

series ordinal

3

1 reference

31 July 2017

5 August 2010

1 reference

American Journal of Physiology - Gastrointestinal and Liver Physiology

31 July 2017

1 reference

31 July 2017

299

1 reference

31 July 2017

G935-45

1 reference

31 July 2017

4

1 reference

Protection of epithelial barrier function by the Crohn's disease associated gene protein tyrosine phosphatase n2

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

Mechanism of interferon-gamma-induced increase in T84 intestinal epithelial tight junction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

Epithelial restitution and wound healing in inflammatory bowel disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

Juxtacrine activation of EGFR regulates claudin expression and increases transepithelial resistance

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

Consequences of direct versus indirect activation of epidermal growth factor receptor in intestinal epithelial cells are dictated by protein-tyrosine phosphatase 1B.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

Phosphatidylinositol 3'-kinase is a critical mediator of interferon-gamma-induced increases in enteric epithelial permeability.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

Cellular and molecular mechanisms of the epithelial repair in IBD.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

Negative regulation of EGFR signalling through integrin-alpha1beta1-mediated activation of protein tyrosine phosphatase TCPTP

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

Gs protein-coupled receptor agonists induce transactivation of the epidermal growth factor receptor in T84 cells: implications for epithelial secretory responses.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

The nuclear isoform of protein-tyrosine phosphatase TC-PTP regulates interleukin-6-mediated signaling pathway through STAT3 dephosphorylation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

Combinatorial control of the specificity of protein tyrosine phosphatases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

Regulation of the p85/p110alpha phosphatidylinositol 3'-kinase. Distinct roles for the n-terminal and c-terminal SH2 domains

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

ErbB-1 and ErbB-2 acquire distinct signaling properties dependent upon their dimerization partner

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

Regulation of the p85/p110 phosphatidylinositol 3'-kinase: stabilization and inhibition of the p110alpha catalytic subunit by the p85 regulatory subunit

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

Akt is a direct target of the phosphatidylinositol 3-kinase. Activation by growth factors, v-src and v-Ha-ras, in Sf9 and mammalian cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

Phosphatidylinositol 3-kinase mediates the inhibitory effect of epidermal growth factor on calcium-dependent chloride secretion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

Epidermal growth factor inhibits Ca(2+)-dependent Cl- transport in T84 human colonic epithelial cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

Epidermal growth factor-related peptides activate distinct subsets of ErbB receptors and differ in their biological activities

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

Phosphoinositide 3-kinase is activated by phosphopeptides that bind to the SH2 domains of the 85-kDa subunit

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

The MAPK signaling cascade

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

Occluding junction structure-function relationships in a cultured epithelial monolayer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

Synergistic action of cyclic adenosine monophosphate- and calcium-mediated chloride secretion in a colonic epithelial cell line

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

Altered intestinal chloride transport in cystic fibrosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

All autophosphorylation sites of epidermal growth factor (EGF) receptor and HER2/neu are located in their carboxyl-terminal tails. Identification of a novel site in EGF receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

Increased epidermal growth factor receptor gene expression by gamma-interferon in a human breast carcinoma cell line

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

A site of tyrosine phosphorylation in the C terminus of the epidermal growth factor receptor is required to activate phospholipase C.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

SH2 domains prevent tyrosine dephosphorylation of the EGF receptor: identification of Tyr992 as the high-affinity binding site for SH2 domains of phospholipase C gamma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957338

Persistent epithelial dysfunction and bacterial translocation after resolution of intestinal inflammation

28 July 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00106.2010

Key role of PKC and Ca2+ in EGF protection of microtubules and intestinal barrier against oxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00106.2010

Prolonged interferon-gamma exposure decreases ion transport, NKCC1, and Na+-K+-ATPase expression in human intestinal xenografts in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00106.2010

Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00106.2010

Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00106.2010

Decreased expression of apical Na+ channels and basolateral Na+, K+-ATPase in ulcerative colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00106.2010

p38 mitogen-activated protein kinase inhibits calcium-dependent chloride secretion in T84 colonic epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00106.2010

Carbachol stimulates transactivation of epidermal growth factor receptor and mitogen-activated protein kinase in T84 cells. Implications for carbachol-stimulated chloride secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00106.2010

Transactivation of the epidermal growth factor receptor in colonic epithelial cells by carbachol requires extracellular release of transforming growth factor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00106.2010

Experimental inflammation of the rat distal colon inhibits ion secretion in the proximal colon by affecting the enteric nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00106.2010

Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00106.2010

Inhibition of Na+,K+-ATPase by interferon gamma down-regulates intestinal epithelial transport and barrier function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00106.2010

Identification of a nuclear Stat1 protein tyrosine phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00106.2010

Epidermal growth factor receptor and the adaptor protein p52Shc are specific substrates of T-cell protein tyrosine phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00106.2010

The protein-tyrosine phosphatase TCPTP regulates epidermal growth factor receptor-mediated and phosphatidylinositol 3-kinase-dependent signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00106.2010

Interferon-gamma activates EGF receptor and increases TGF-alpha in T84 cells: implications for chloride secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00106.2010

Activation of AMP-activated protein kinase reduces cAMP-mediated epithelial chloride secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00106.2010

Arginine methylation of STAT1 regulates its dephosphorylation by T cell protein tyrosine phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00106.2010

Prolonged colonic epithelial hyporesponsiveness after colitis: role of inducible nitric oxide synthase

21 January 2018

1 reference

12 December 2020

Interferon gamma-dependent transactivation of epidermal growth factor receptor

1 reference

12 December 2020

Association of interferon-gamma induced growth inhibition and modulation of epidermal growth factor receptor gene expression in squamous cell carcinoma cell lines

1 reference

12 December 2020

Cellular basis for defective electrolyte transport in inflamed human colon

1 reference

12 December 2020

Identifiers

DOI

10.1152/AJPGI.00106.2010

1 reference

31 July 2017

1 reference

31 July 2017

1 reference

PubMed ID

20689057