Increased AMP:ATP ratio and AMP-activated protein kinase activity during cellular senescence linked to reduced HuR function (Q34194696)

31 July 2017

Increased AMP:ATP ratio and AMP-activated protein kinase activity during cellular senescence linked to reduced HuR function (English)

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31 July 2017

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Isabel López de Silanes

object named as

Isabel López de Silanes

3

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David Carling

object named as

David Carling

4

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Myriam Gorospe

5

object named as

Myriam Gorospe

1 reference

31 July 2017

Wengong Wang

1

1 reference

PubMed ID

12730239

31 July 2017

Xiaoling Yang

2

1 reference

PubMed ID

12730239

31 July 2017

language of work or name

English

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publication date

1 May 2003

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Journal of Biological Chemistry

31 July 2017

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31 July 2017

278

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31 July 2017

27016-27023

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31 July 2017

29

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The AMP-activated protein kinase--fuel gauge of the mammalian cell?

31 July 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

AMP-activated protein kinase isoenzyme family: subunit structure and chromosomal location

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

AMP-activated protein kinase: the energy charge hypothesis revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

Regulation of transcription by AMP-activated protein kinase: phosphorylation of p300 blocks its interaction with nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

Regulation of the forkhead transcription factor FKHR (FOXO1a) by glucose starvation and AICAR, an activator of AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

AMP-activated kinase regulates cytoplasmic HuR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

HNS, a nuclear-cytoplasmic shuttling sequence in HuR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

Why is Hu where? Shuttling of early-response-gene messenger RNA subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

HuR regulates p21 mRNA stabilization by UV light

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

Ectopic expression of Hel-N1, an RNA-binding protein, increases glucose transporter (GLUT1) expression in 3T3-L1 adipocytes

21 January 2018

1 reference

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p21(waf1) mRNA contains a conserved element in its 3'-untranslated region that is bound by the Elav-like mRNA-stabilizing proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

AU-rich elements: characterization and importance in mRNA degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

Modulation of the fate of cytoplasmic mRNA by AU-rich elements: key sequence features controlling mRNA deadenylation and decay

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin

21 January 2018

1 reference

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Identification of TIAR as a protein binding to the translational regulatory AU-rich element of tumor necrosis factor alpha mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

Purification, characterization, and cDNA cloning of an AU-rich element RNA-binding protein, AUF1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

Loss of HuR is linked to reduced expression of proliferative genes during replicative senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

Reversible cellular senescence: implications for immortalization of normal human diploid fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

Inhibition of G1 cyclin-dependent kinase activity during growth arrest of human breast carcinoma cells by prostaglandin A2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

The Anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

Genes involved in senescence and immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

Mitochondrial alterations, cellular response to oxidative stress and defective degradation of proteins in aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

Coherence of subthreshold activity in coupled inferior olivary neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300318200

Protein turnover plays a key role in aging

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M300318200

1 reference

31 July 2017

1 reference

PubMed ID

12730239