Protein turnover plays a key role in aging (Q34445953)

2 August 2017

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title

Protein turnover plays a key role in aging (English)

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2 August 2017

Alexey G Ryazanov

1

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PubMed ID

11718813

2 August 2017

Bradley S Nefsky

series ordinal

2

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2 August 2017

1 January 2002

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Mechanisms of Ageing and Development

2 August 2017

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2 August 2017

123

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2 August 2017

2-3

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2 August 2017

207-213

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Ubiquitin, cellular inclusions and their role in neurodegeneration

2 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

What causes the build-up of ubiquitin-containing inclusions in Parkinson's disease?

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Effect of oxidative stress, produced by cumene hydroperoxide, on the various steps of protein synthesis. Modifications of elongation factor-2

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Delayed aging in Ames dwarf mice. Relationships to endocrine function and body size.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Prolonged longevity of hypopituitary dwarf mice

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Dwarf mice and the ageing process.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity, and loss in temporal and spatial memory by chronic administration of the spin-trapping compound N-tert-butyl-alpha-phenylnitrone.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

When lysosomes get old.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Moderate caloric restriction increases type 1 IGF receptors and protein synthesis in aging rats

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Effect of age and caloric intake on protein oxidation in different brain regions and on behavioral functions of the mouse.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Current status of age altered enzymes: Alternative mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Differential display analysis of gene expression indicates that age-related changes are restricted to a small cohort of genes.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Oxidative stress, aging and the proteasomal system

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Aging: a theory based on free radical and radiation chemistry

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

The experimental manipulation of ageing by diet

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Effect of dietary restriction on the degradation of proteins in senescent mouse liver parenchymal cells in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Programmed aging or error catastrophe? An examination by two-dimensional polyacrylamide gel electrophoresis.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Possible involvement of proteasome inhibition in aging: implications for oxidative stress.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

A C. elegans mutant that lives twice as long as wild type

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Gene expression profile of aging and its retardation by caloric restriction

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

The effects of aging and chronic dietary restriction on whole body growth and protein turnover in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Extended life-span and stress resistance in the Drosophila mutant methuselah

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Protein synthesis and degradation during aging and senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Genetic analysis of ageing: role of oxidative damage and environmental stresses.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

The p66shc adaptor protein controls oxidative stress response and life span in mammals

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Kleemeier award lecture: are there genes for aging?

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Differential longevity in mouse stocks selected for early life growth trajectory

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

The maintenance of the accuracy of protein synthesis and its relevance to ageing

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

The maintenance of the accuracy of protein synthesis and its relevance to ageing: a correction

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Effects of aging on the various steps of protein synthesis: fragmentation of elongation factor 2

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Protein degradation in aged nematodes (Turbatrix aceti)

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Protein and nucleic acid metabolism in organs from mice selected for larger and smaller body size

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Synthesis, modifications, and turnover of proteins during aging

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

I. The relationship between age-related changes in gene expression, protein turnover, and the responsiveness of an organism to stimuli

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Senescence and the accumulation of abnormal proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

The formation of altered enzymes in aging animals

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

The effect of age on enolase turnover in the free-living nematode, Turbatrix aceti

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Protein oxidative damage is associated with life expectancy of houseflies

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Oxidative stress, caloric restriction, and aging

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Protein oxidation and proteolysis during aging and oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Protein modification in aging

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Protein oxidation and aging

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Analysis of the proteins of aging Caenorhabditis elegans by high resolution two-dimensional gel electrophoresis.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Food Restriction Enhances the Proteolytic Capacity of the Aging Rat Liver

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Enhancement by food restriction of liver protein synthesis in the aging Fischer 344 rat

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Total human body protein synthesis in relation to protein requirements at various ages

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

Protein oxidation associated with aging is reduced by dietary restriction of protein or calories

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2801%2900337-2

7 January 2021

10.1016/S0047-6374(01)00337-2

Identifiers

DOI

1 reference

2 August 2017

1 reference

PubMed ID

11718813