Structure-guided reprogramming of human cGAS dinucleotide linkage specificity (Q34148968)

31 July 2017

Structure-guided reprogramming of human cGAS dinucleotide linkage specificity (English)

1 reference

31 July 2017

7

Jennifer A Doudna

1 reference

31 July 2017

1

Philip J Kranzusch

1 reference

31 July 2017

6

James M Berger

1 reference

31 July 2017

Amy S Y Lee

2

1 reference

31 July 2017

Stephen C Wilson

series ordinal

3

1 reference

31 July 2017

Mikhail S Solovykh

series ordinal

4

1 reference

31 July 2017

Russell E Vance

series ordinal

5

1 reference

31 July 2017

language of work or name

English

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publication date

14 August 2014

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31 July 2017

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31 July 2017

158

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31 July 2017

5

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31 July 2017

1011-1021

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The cGAS-cGAMP-STING pathway of cytosolic DNA sensing and signaling

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

Structural and Functional Analyses of DNA-Sensing and Immune Activation by Human cGAS

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

Cyclic dinucleotides and the innate immune response

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

Structure-Function Analysis of STING Activation by c[G(2′,5′)pA(3′,5′)p] and Targeting by Antiviral DMXAA

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

Structural mechanism of cytosolic DNA sensing by cGAS

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

Structure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate Immunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

Structural basis for cytosolic double-stranded RNA surveillance by human oligoadenylate synthetase 1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

The prokaryote messenger c-di-GMP triggers stalk cell differentiation in Dictyostelium.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

Linking Crystallographic Model and Data Quality

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

Coordinated regulation of accessory genetic elements produces cyclic di-nucleotides for V. cholerae virulence

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

Arenavirus Z protein controls viral RNA synthesis by locking a polymerase-promoter complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

Linear ubiquitin assembly complex negatively regulates RIG-I- and TRIM25-mediated type I interferon induction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

Identification and characterization of a loss-of-function human MPYS variant

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

PHENIX: a comprehensive Python-based system for macromolecular structure solution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

Ribose 2'-O Methylation of the Vesicular Stomatitis Virus mRNA Cap Precedes and Facilitates Subsequent Guanine-N-7 Methylation by the Large Polymerase Protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

Regulation of cellulose synthesis in Acetobacter xylinum by cyclic diguanylic acid

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

Structural biochemistry of a bacterial checkpoint protein reveals diadenylate cyclase activity regulated by DNA recombination intermediates

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

Phosphorylation-Independent Regulation of the Diguanylate Cyclase WspR

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

Recognition of cytosolic DNA activates an IRF3-dependent innate immune response

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

Coot: model-building tools for molecular graphics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

Structural basis of activity and allosteric control of diguanylate cyclase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

Mechanism of transfer RNA maturation by CCA-adding enzyme without using an oligonucleotide template

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

WebLogo: A Sequence Logo Generator

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

Reciprocal-space solvent flattening

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157622

MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

5 July 2018

1 reference

20 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1093/MOLBEV/MST010

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2014.07.028

PROMALS3D: a tool for multiple protein sequence and structure alignments

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2014.07.028

Global indicators of X-ray data quality

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2014.07.028

MolProbity: all-atom structure validation for macromolecular crystallography

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2014.07.028

Identifiers

DOI

10.1016/J.CELL.2014.07.028

1 reference

31 July 2017

1 reference

31 July 2017

1 reference