Ricin Toxin Activates the NALP3 Inflammasome (Q34141940)

31 July 2017

Ricin Toxin Activates the NALP3 Inflammasome (English)

1 reference

31 July 2017

1 reference

John Wong

2

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author name string

Meghan Lindauer

series ordinal

1

1 reference

PubMed ID

20862209

31 July 2017

Bruce Magun

series ordinal

3

1 reference

31 July 2017

1 June 2010

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31 July 2017

1 reference

31 July 2017

2

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31 July 2017

6

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31 July 2017

1500-1514

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Creative Commons Attribution 4.0 International

31 July 2017

start time

17 June 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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1 reference

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5 July 2018

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Thioredoxin-interacting protein links oxidative stress to inflammasome activation

5 July 2018

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Inflammasomes: too big to miss

5 July 2018

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5 July 2018

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Pulmonary inflammation triggered by ricin toxin requires macrophages and IL-1 signaling

5 July 2018

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An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans

5 July 2018

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The inflammasomes: guardians of the body

5 July 2018

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Inflammasome recognition of influenza virus is essential for adaptive immune responses

5 July 2018

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Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

5 July 2018

1 reference

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The NALP3 inflammasome is involved in the innate immune response to amyloid-beta

5 July 2018

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The Nalp3 inflammasome is essential for the development of silicosis

5 July 2018

1 reference

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Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

5 July 2018

1 reference

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ZAK: a MAP3Kinase that transduces Shiga toxin- and ricin-induced proinflammatory cytokine expression.

5 July 2018

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A quantitative analysis of kinase inhibitor selectivity

5 July 2018

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COPs and POPs: modulators of inflammasome activity

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The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation

5 July 2018

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Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942780

Intrapulmonary delivery of ricin at high dosage triggers a systemic inflammatory response and glomerular damage

5 July 2018

1 reference

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ASC, Ipaf and Cryopyrin/Nalp3: bona fide intracellular adapters of the caspase-1 inflammasome

5 July 2018

1 reference

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Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation

5 July 2018

1 reference

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Role of apoptotic signaling pathways in regulation of inflammatory responses to ricin in primary murine macrophages

5 July 2018

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ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages

5 July 2018

1 reference

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Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942780

Cryopyrin activates the inflammasome in response to toxins and ATP

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942780

Gout-associated uric acid crystals activate the NALP3 inflammasome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942780

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942780

NLRs join TLRs as innate sensors of pathogens

5 July 2018

1 reference

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Administration of ricin induces a severe inflammatory response via nonredundant stimulation of ERK, JNK, and P38 MAPK and provides a mouse model of hemolytic uremic syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942780

NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942780

NALPs: a novel protein family involved in inflammation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942780

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942780

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942780

Microbiological, biological, and chemical weapons of warfare and terrorism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942780

The PYRIN-CARD protein ASC is an activating adaptor for caspase-1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942780

Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942780

Ribotoxic stress response: activation of the stress-activated protein kinase JNK1 by inhibitors of the peptidyl transferase reaction and by sequence-specific RNA damage to the alpha-sarcin/ricin loop in the 28S rRNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942780

Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942780

Potassium-inhibited processing of IL-1 beta in human monocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942780

A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942780

Caspase-1 inflammasomes: choosing between death and taxis.

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.3390%2FTOXINS2061500

Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.3390%2FTOXINS2061500

Use of ricin a-chain to selectively deplete Kupffer cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20862209

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Ultrastructure of rat lung following inhalation of ricin aerosol

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20862209

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3390/TOXINS2061500

1 reference

31 July 2017

1 reference

31 July 2017

1 reference

PubMed ID

20862209