Tbx3 impinges on the p53 pathway to suppress apoptosis, facilitate cell transformation and block myogenic differentiation (Q24298312)

positive regulation of cell cycle

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Hanqian Carlson

1

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Sara Ota

2

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Youngsup Song

3

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Yanwen Chen

4

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Peter J Hurlin

Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome

5

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language of work or name

English

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publication date

30 May 2002

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published in

Oncogene

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volume

21

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page(s)

3827-35

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issue

24

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cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

The spectrum of mutations in TBX3: Genotype/Phenotype relationship in ulnar-mammary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

The T-box transcription factor gene TBX22 is mutated in X-linked cleft palate and ankyloglossia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

TBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

A dominant repression domain in Tbx3 mediates transcriptional repression and cell immortalization: relevance to mutations in Tbx3 that cause ulnar-mammary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

Heterozygous germline mutations in the p53 homolog p63 are the cause of EEC syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

Expression of the T-box family genes, Tbx1-Tbx5, during early mouse development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

Proliferation, cell cycle and apoptosis in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

Expression of T-box genes Tbx2-Tbx5 during chick organogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

Transcription repression by Xenopus ET and its human ortholog TBX3, a gene involved in ulnar-mammary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

Cloning of the T gene required in mesoderm formation in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

Split-hand/split-foot malformation is caused by mutations in the p63 gene on 3q27.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

Twist is a potential oncogene that inhibits apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

c-Myc regulates cyclin D-Cdk4 and -Cdk6 activity but affects cell cycle progression at multiple independent points

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

Hay-Wells syndrome is caused by heterozygous missense mutations in the SAM domain of p63

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

The INK4A/ARF locus and its two gene products

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

T-box genes: what they do and how they do it.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

p63 Gene mutations in eec syndrome, limb-mammary syndrome, and isolated split hand-split foot malformation suggest a genotype-phenotype correlation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

Cell cycle exit upon myogenic differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

Abrogation of retinoblastoma protein function by c-Abl through tyrosine kinase-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

p19ARF links the tumour suppressor p53 to Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

p53 is involved in the differentiation but not in the differentiation-associated apoptosis of myoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

7 January 2021

Deconstructing DiGeorge syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

7 January 2021

Ulnar-mammary syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

7 January 2021

Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205476

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205476

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

2140483

1027021665

0 references

Fatcat ID

release_yftvlqfxtnguddt2ukpjlgruoa

0 references

2140483

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference