PTP1B antisense oligonucleotide lowers PTP1B protein, normalizes blood glucose, and improves insulin sensitivity in diabetic mice (Q34038299)

30 July 2017

PTP1B antisense oligonucleotide lowers PTP1B protein, normalizes blood glucose, and improves insulin sensitivity in diabetic mice (English)

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30 July 2017

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Bradley A Zinker

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30 July 2017

Cristina M Rondinone

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30 July 2017

James M Trevillyan

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30 July 2017

Rebecca J Gum

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30 July 2017

Jill E Clampit

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30 July 2017

Jeffrey F Waring

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30 July 2017

Nancy Xie

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30 July 2017

Denise Wilcox

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30 July 2017

Peer Jacobson

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30 July 2017

Leigh Frost

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30 July 2017

Paul E Kroeger

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30 July 2017

Regina M Reilly

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30 July 2017

Sandra Koterski

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30 July 2017

Terry J Opgenorth

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30 July 2017

Roger G Ulrich

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30 July 2017

Seth Crosby

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30 July 2017

Madeline Butler

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30 July 2017

Susan F Murray

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30 July 2017

Robert A McKay

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30 July 2017

Sanjay Bhanot

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30 July 2017

Brett P Monia

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30 July 2017

Michael R Jirousek

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30 July 2017

language of work or name

English

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publication date

8 August 2002

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Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

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30 July 2017

99

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30 July 2017

11357-11362

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30 July 2017

17

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Protein tyrosine phosphatase-1B in diabetes

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123261

Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123261

A review of the issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123261

Novel mechanisms for antisense-mediated regulation of gene expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123261

Tyrosine dephosphorylation and deactivation of insulin receptor substrate-1 by protein-tyrosine phosphatase 1B. Possible facilitation by the formation of a ternary complex with the Grb2 adaptor protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123261

Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123261

Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123261

Increased insulin sensitivity and hypoglycaemia in mice lacking the p85 alpha subunit of phosphoinositide 3-kinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123261

Activation of protein kinase B/Akt is sufficient to repress the glucocorticoid and cAMP induction of phosphoenolpyruvate carboxykinase gene.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123261

The IRS-signalling system: a network of docking proteins that mediate insulin action

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123261

Mechanism of activation and function of protein kinase B.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123261

Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123261

Insulin stimulates the phosphorylation of the 66- and 52-kilodalton Shc isoforms by distinct pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123261

p85alpha gene generates three isoforms of regulatory subunit for phosphatidylinositol 3-kinase (PI 3-Kinase), p50alpha, p55alpha, and p85alpha, with different PI 3-kinase activity elevating responses to insulin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123261

Mechanism of activation of protein kinase B by insulin and IGF-1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123261

Cellular and molecular mechanisms of non-insulin dependent diabetes mellitus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123261

Progress in antisense oligonucleotide therapeutics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123261

Protein-tyrosine phosphatase 1B is a negative regulator of insulin- and insulin-like growth factor-I-stimulated signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123261

Insulin regulation of phosphoenolpyruvate carboxykinase gene expression does not require activation of the Ras/mitogen-activated protein kinase signaling pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123261

Banting Lecture. Insulin action, diabetogenes, and the cause of type II diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123261

Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123261

Tyrosine-specific protein kinase activity is associated with the purified insulin receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123261

Cellular mechanisms of insulin resistance in non-insulin-dependent (type II) diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123261

Banting lecture 1988. Role of insulin resistance in human disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123261

Activation of phosphatidylinositol 3-kinase by insulin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123261

Insulin-stimulated glucose transport minireview series

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.142298199

Phosphorylation and Activation of Heart 6-Phosphofructo-2-kinase by Protein Kinase B and Other Protein Kinases of the Insulin Signaling Cascades

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.142298199

Phosphatidylinositol 3-Kinase, but Not p70/p85 Ribosomal S6 Protein Kinase, Is Required for the Regulation of Phosphoenolpyruvate Carboxykinase (PEPCK) Gene Expression by Insulin

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.142298199

Signalling pathways involved in the stimulation of glycogen synthesis by insulin in rat hepatocytes

21 January 2018

1 reference

12 December 2020

Signaling mechanisms that regulate glucose transport

1 reference

12 December 2020

Autophosphorylation of the insulin receptor in vitro. Designation of phosphorylation sites and correlation with receptor kinase activation

1 reference

12 December 2020

Signaling pathway involved in the activation of heart 6-phosphofructo-2-kinase by insulin

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.142298199

1 reference

30 July 2017

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30 July 2017

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