Mechanism of activation and function of protein kinase B. (Q41732739)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9529606%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

title

Mechanism of activation and function of protein kinase B (English)

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10 November 2019

1

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10 November 2019

author name string

P Cohen

series ordinal

2

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10 November 2019

publication date

1 February 1998

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Current Opinion in Genetics & Development

10 November 2019

published in

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10 November 2019

volume

8

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10 November 2019

issue

1

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10 November 2019

page(s)

55-62

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publication type of scholarly work

10 November 2019

review article

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Molecular cloning and characterisation of a novel putative protein-serine kinase related to the cAMP-dependent and protein kinase C families

cites work

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7 January 2021

Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily

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7 January 2021

AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Molecular cloning and characterization of a new member of the RAC protein kinase family: association of the pleckstrin homology domain of three types of RAC protein kinase with protein kinase C subspecies and beta gamma subunits of G proteins

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

PH domains: diverse sequences with a common fold recruit signaling molecules to the cell surface

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

The pleckstrin homology domain: an intriguing multifunctional protein module

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7 January 2021

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

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7 January 2021

Inositol lipid 5-phosphatases--traffic signals and signal traffic.

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7 January 2021

Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation

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7 January 2021

High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain.

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

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7 January 2021

Dual Role of Phosphatidylinositol-3,4,5-trisphosphate in the Activation of Protein Kinase B

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Mechanism of activation of protein kinase B by insulin and IGF-1

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation

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7 January 2021

Role of translocation in the activation and function of protein kinase B

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Mitogenic Activation, Phosphorylation, and Nuclear Translocation of Protein Kinase Bβ

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Regulation of protein kinase B in rat adipocytes by insulin, vanadate, and peroxovanadate. Membrane translocation in response to peroxovanadate

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Protein kinase C: structure, function, and regulation

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

The modular phosphorylation and activation of p70s6k.

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Further evidence that the inhibition of glycogen synthase kinase‐3β by IGF‐1 is mediated by PDK1/PKB‐induced phosphorylation of Ser‐9 and not by dephosphorylation of Tyr‐216

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

PDK1, one of the missing links in insulin signal transduction?1

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Regulation of eukaryotic initiation factor eIF2B: glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Phosphorylation and Activation of Heart 6-Phosphofructo-2-kinase by Protein Kinase B and Other Protein Kinases of the Insulin Signaling Cascades

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Regulation of neuronal survival by the serine-threonine protein kinase Akt

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase

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7 January 2021

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Interleukin-3-Induced Phosphorylation of BAD Through the Protein Kinase Akt

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Identification of Regulatory Phosphorylation Sites in Mitogen-activated Protein Kinase (MAPK)-activated Protein Kinase-1a/p90 That Are Inducible by MAPK

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

Phosphorylation and activation of p70s6k by PDK1

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980062-2

7 January 2021

10.1016/S0959-437X(98)80062-2

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9529606%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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