A novel "molecular tweezer" inhibitor of α-synuclein neurotoxicity in vitro and in vivo. (Q34030874)

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24 January 2020

title

A novel "molecular tweezer" inhibitor of α-synuclein neurotoxicity in vitro and in vivo (English)

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24 January 2020

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Mark Stahl

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24 January 2020

author name string

Shubhangi Prabhudesai

1

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Aida Attar

3

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Aswani Kotagiri

4

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24 January 2020

Arthur G Fitzmaurice

5

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24 January 2020

Rajeswari Lakshmanan

6

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24 January 2020

Magdalena I Ivanova

7

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24 January 2020

Joseph A Loo

8

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24 January 2020

Frank-Gerrit Klärner

9

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24 January 2020

Thomas Schrader

10

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24 January 2020

Gal Bitan

12

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24 January 2020

Jeff M Bronstein

13

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publication date

1 April 2012

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24 January 2020

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24 January 2020

volume

9

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24 January 2020

issue

2

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24 January 2020

page(s)

464-476

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https://scigraph.springernature.com/pub.10.1007/s13311-012-0105-1

24 January 2020

exact match

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29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy

29 October 2018

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Proteasomal inhibition causes loss of nigral tyrosine hydroxylase neurons.

29 October 2018

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29 October 2018

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Failure of proteasome inhibitor administration to provide a model of Parkinson's disease in rats and monkeys.

29 October 2018

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Lack of nigrostriatal pathology in a rat model of proteasome inhibition.

29 October 2018

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A molecular tweezer for lysine and arginine

29 October 2018

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Neurotoxic protein oligomers--what you see is not always what you get.

29 October 2018

1 reference

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Rifampicin inhibits alpha-synuclein fibrillation and disaggregates fibrils

29 October 2018

1 reference

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Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector

29 October 2018

1 reference

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Dopamine and L-dopa disaggregate amyloid fibrils: implications for Parkinson's and Alzheimer's disease

29 October 2018

1 reference

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Aggregated and monomeric alpha-synuclein bind to the S6' proteasomal protein and inhibit proteasomal function

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337029

Failure of the ubiquitin-proteasome system in Parkinson's disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337029

Impairment of the ubiquitin-proteasome system by protein aggregation

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337029

Proteasomal function is impaired in substantia nigra in Parkinson's disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337029

Dark-induced changes in activity and compartmentalization of retinal calmodulin kinase in the rat

29 October 2018

1 reference

12 December 2020

Genetics of Parkinson's disease

1 reference

12 December 2020

[18] Quantification of β-sheet amyloid fibril structures with thioflavin T

1 reference

12 December 2020

Proteasome inhibitor-induced model of Parkinson's disease

1 reference

12 December 2020

alpha-Synuclein protofibrils inhibit 26 S proteasome-mediated protein degradation: understanding the cytotoxicity of protein protofibrils in neurodegenerative disease pathogenesis.

1 reference

12 December 2020

Clues to how alpha-synuclein damages neurons in Parkinson's disease

1 reference

12 December 2020

10.1007/S13311-012-0105-1

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22373667%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22373667%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference

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