Ziram causes dopaminergic cell damage by inhibiting E1 ligase of the proteasome. (Q41177193)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18818210%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

title

Ziram causes dopaminergic cell damage by inhibiting E1 ligase of the proteasome (English)

1 reference

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14 January 2020

1 reference

ChEBI release 2020-05-28

1 reference

Pierre-Olivier Fernagut

7

1 reference

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14 January 2020

Farzad Mortazavi

8

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14 January 2020

4

John E Casida

1 reference

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14 January 2020

author name string

Arthur P Chou

1

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14 January 2020

Nigel Maidment

2

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14 January 2020

Rebecka Klintenberg

3

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14 January 2020

Sharon Li

5

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14 January 2020

Arthur G Fitzmaurice

6

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14 January 2020

Jeff M Bronstein

10

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14 January 2020

Marie-Francoise Chesselet

9

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14 January 2020

language of work or name

English

0 references

publication date

25 September 2008

1 reference

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Journal of Biological Chemistry

14 January 2020

published in

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14 January 2020

volume

283

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14 January 2020

issue

50

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14 January 2020

page(s)

34696-34703

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Proteasome inhibition and Parkinson's disease modeling

14 January 2020

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27 September 2017

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27 September 2017

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Proteasomal inhibition induced by manganese ethylene-bis-dithiocarbamate: relevance to Parkinson's disease

27 September 2017

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Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease

27 September 2017

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27 September 2017

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Localization of alpha-, beta-, and gamma-synuclein during neuronal development and alterations associated with the neuronal response to axonal trauma

27 September 2017

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Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat

27 September 2017

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Glutathione decreases in dopaminergic PC12 cells interfere with the ubiquitin protein degradation pathway: relevance for Parkinson's disease?

27 September 2017

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Impairment of the ubiquitin-proteasome system by protein aggregation

27 September 2017

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The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: implications for Parkinson's disease.

27 September 2017

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

27 September 2017

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Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator

27 September 2017

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Early effects of intrastriatal injections of quinolinic acid on microtubule-associated protein-2 and neuropeptides in rat basal ganglia

27 September 2017

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S-methylation as a bioactivation mechanism for mono- and dithiocarbamate pesticides as aldehyde dehydrogenase inhibitors

17 June 2018

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Identified postnatal mesolimbic dopamine neurons in culture: morphology and electrophysiology.

17 June 2018

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Pesticide exposure and self-reported Parkinson's disease in the agricultural health study.

17 June 2018

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Proteasomal inhibition causes loss of nigral tyrosine hydroxylase neurons.

19 August 2018

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Failure of proteasome inhibitor administration to provide a model of Parkinson's disease in rats and monkeys.

19 August 2018

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Lack of nigrostriatal pathology in a rat model of proteasome inhibition.

19 August 2018

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Dopaminergic neurons in rat ventral midbrain cultures undergo selective apoptosis and form inclusions, but do not up-regulate iHSP70, following proteasomal inhibition

19 August 2018

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Disrupted compaction of CNS myelin in an OSP/Claudin-11 and PLP/DM20 double knockout mouse.

19 August 2018

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3,4-dihydroxyphenylalanine reverses the motor deficits in Pitx3-deficient aphakia mice: behavioral characterization of a novel genetic model of Parkinson's disease.

19 August 2018

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19 August 2018

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alpha-synuclein is required for the fibrillar nature of ubiquitinated inclusions induced by proteasomal inhibition in primary neurons.

19 August 2018

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Dysfunction of mitochondrial complex I and the proteasome: interactions between two biochemical deficits in a cellular model of Parkinson's disease.

19 August 2018

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19 August 2018

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Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons

19 August 2018

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Impairment of the ubiquitin-proteasome system causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures

19 August 2018

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19 August 2018

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Proteasomal function is impaired in substantia nigra in Parkinson's disease

19 August 2018

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19 August 2018

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Dialkyldithiocarbamates inhibit tyrosine hydroxylase activity in PC12 cells and in fibroblasts that express tyrosine hydroxylase

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18818210

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Dithiocarbamate toxicity toward thymocytes involves their copper-catalyzed conversion to thiuram disulfides, which oxidize glutathione in a redox cycle without the release of reactive oxygen species

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18818210

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Proteasome inhibitor-induced model of Parkinson's disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18818210

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M802210200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18818210%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18818210%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference