Getting the mOST from OST: Role of organic solute transporter, OSTalpha-OSTbeta, in bile acid and steroid metabolism (Q34024552)

30 July 2017

1 reference

title

Getting the mOST from OST: Role of organic solute transporter, OSTalpha-OSTbeta, in bile acid and steroid metabolism (English)

1 reference

30 July 2017

Paul A Dawson

1

1 reference

30 July 2017

Melissa L Hubbert

series ordinal

2

1 reference

30 July 2017

Anuradha Rao

series ordinal

3

1 reference

30 July 2017

language of work or name

English

0 references

publication date

9 June 2010

1 reference

Biochimica et Biophysica Acta

30 July 2017

1 reference

30 July 2017

1801

1 reference

30 July 2017

994-1004

1 reference

30 July 2017

9

1 reference

Bile acids and their nuclear receptor FXR: Relevance for hepatobiliary and gastrointestinal disease

30 July 2017

1 reference

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Hepatocyte nuclear factor 1alpha and beta control terminal differentiation and cell fate commitment in the gut epithelium

28 July 2018

1 reference

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Genome-wide tissue-specific farnesoid X receptor binding in mouse liver and intestine.

28 July 2018

1 reference

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Mouse organic solute transporter alpha deficiency enhances renal excretion of bile acids and attenuates cholestasis

28 July 2018

1 reference

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Asparagine-linked oligosaccharides present on a non-consensus amino acid sequence in the CH1 domain of human antibodies

28 July 2018

1 reference

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Bile salts of vertebrates: structural variation and possible evolutionary significance

28 July 2018

1 reference

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Bile acid transporters

1 reference

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Compensatory induction of liver efflux transporters in response to ANIT-induced liver injury is impaired in FXR-null mice.

28 July 2018

1 reference

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Bile acids as regulatory molecules

28 July 2018

1 reference

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28 July 2018

1 reference

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28 July 2018

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28 July 2018

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N-Glycosylation of the alpha subunit does not influence trafficking or functional activity of the human organic solute transporter alpha/beta

28 July 2018

1 reference

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1 reference

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GATA4 is essential for jejunal function in mice

28 July 2018

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28 July 2018

1 reference

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Ostalpha-Ostbeta is required for bile acid and conjugated steroid disposition in the intestine, kidney, and liver

28 July 2018

1 reference

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Bile acids: chemistry, pathochemistry, biology, pathobiology, and therapeutics

28 July 2018

1 reference

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28 July 2018

1 reference

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The organic solute transporter alpha-beta, Ostalpha-Ostbeta, is essential for intestinal bile acid transport and homeostasis

28 July 2018

1 reference

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Immunolocalization of farnesoid X receptor (FXR) in mouse tissues using tissue microarray

28 July 2018

1 reference

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The pharmacological exploitation of cholesterol 7alpha-hydroxylase, the key enzyme in bile acid synthesis: from binding resins to chromatin remodelling to reduce plasma cholesterol.

28 July 2018

1 reference

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FXR agonists and FGF15 reduce fecal bile acid excretion in a mouse model of bile acid malabsorption

28 July 2018

1 reference

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Insights in the regulation of cholesterol 7alpha-hydroxylase gene reveal a target for modulating bile acid synthesis.

28 July 2018

1 reference

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Heterodimerization, trafficking and membrane topology of the two proteins, Ost alpha and Ost beta, that constitute the organic solute and steroid transporter

28 July 2018

1 reference

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Hepatoprotective role of PXR activation and MRP3 in cholic acid-induced cholestasis.

28 July 2018

1 reference

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Gata4 is essential for the maintenance of jejunal-ileal identities in the adult mouse small intestine

28 July 2018

1 reference

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Role of nuclear receptors in the adaptive response to bile acids and cholestasis: pathogenetic and therapeutic considerations.

28 July 2018

1 reference

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Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents

28 July 2018

1 reference

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Regulation of the mouse organic solute transporter alpha-beta, Ostalpha-Ostbeta, by bile acids

28 July 2018

1 reference

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Bile salt biotransformations by human intestinal bacteria

28 July 2018

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The nuclear receptor for bile acids, FXR, transactivates human organic solute transporter-alpha and -beta genes

28 July 2018

1 reference

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FXR regulates organic solute transporters alpha and beta in the adrenal gland, kidney, and intestine

28 July 2018

1 reference

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Biology of a novel organic solute and steroid transporter, OSTalpha-OSTbeta

28 July 2018

1 reference

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Nuclear receptor ligands: rational and effective therapy for chronic cholestatic liver disease?

28 July 2018

1 reference

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ERAD: the long road to destruction

28 July 2018

1 reference

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28 July 2018

1 reference

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Molecular regulation of hepatobiliary transport systems: clinical implications for understanding and treating cholestasis

28 July 2018

1 reference

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28 July 2018

1 reference

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The heteromeric organic solute transporter alpha-beta, Ostalpha-Ostbeta, is an ileal basolateral bile acid transporter

28 July 2018

1 reference

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1 reference

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28 July 2018

1 reference

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28 July 2018

1 reference

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1 reference

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Functional Complementation between a Novel Mammalian Polygenic Transport Complex and an Evolutionarily Ancient Organic Solute Transporter, OSTα-OSTβ

28 July 2018

1 reference

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1 reference

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1 reference

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28 July 2018

1 reference

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28 July 2018

1 reference

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Sucrase-isomaltase gene transcription requires the hepatocyte nuclear factor-1 (HNF-1) regulatory element and is regulated by the ratio of HNF-1 alpha to HNF-1 beta

28 July 2018

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28 July 2018

1 reference

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28 July 2018

1 reference

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28 July 2018

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28 July 2018

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28 July 2018

1 reference

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28 July 2018

1 reference

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28 July 2018

1 reference

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Disruption of cholesterol 7alpha-hydroxylase gene in mice. II. Bile acid deficiency is overcome by induction of oxysterol 7alpha-hydroxylase.

28 July 2018

1 reference

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Human dehydroepiandrosterone sulfotransferase. Purification, molecular cloning, and characterization.

28 July 2018

1 reference

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Sodium-coupled taurocholate transport in the proximal convolution of the rat kidney in vivo and in vitro

28 July 2018

1 reference

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Determination of acid surface pH in vivo in rat proximal jejunum

28 July 2018

1 reference

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Physicochemical properties of bile acids and their relationship to biological properties: an overview of the problem

28 July 2018

1 reference

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Active and passive bile acid absorption in man. Perfusion studies of the ileum and jejunum

28 July 2018

1 reference

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Taurocholate transport by rat intestinal basolateral membrane vesicles. Evidence for the presence of an anion exchange transport system

28 July 2018

1 reference

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Transport of bile acids in a human intestinal epithelial cell line, Caco-2.

28 July 2018

1 reference

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28 July 2018

1 reference

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28 July 2018

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Colonic absorption of unconjugated bile acids: perfusion studies in man

28 July 2018

1 reference

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Targeted metabolomics identifies glucuronides of dietary phytoestrogens as a major class of MRP3 substrates in vivo.

28 July 2018

1 reference

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Expression and regulation of the bile acid transporter, OSTalpha-OSTbeta in rat and human intestine and liver.

29 October 2018

1 reference

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Bile acids: regulation of synthesis

29 October 2018

1 reference

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OST alpha-OST beta: a key membrane transporter of bile acids and conjugated steroids

29 October 2018

1 reference

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Tissue-specific amino acid transporter partners ACE2 and collectrin differentially interact with hartnup mutations.

29 October 2018

1 reference

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Reduced ileal expression of OSTalpha-OSTbeta in non-obese gallstone disease.

29 October 2018

1 reference

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Expression of bile acid synthesis and detoxification enzymes and the alternative bile acid efflux pump MRP4 in patients with primary biliary cirrhosis

29 October 2018

1 reference

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Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21

29 October 2018

1 reference

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Protein-protein interactions and membrane localization of the human organic solute transporter

29 October 2018

1 reference

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New perspectives for the treatment of cholestasis: lessons from basic science applied clinically

29 October 2018

1 reference

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Circulating intestinal fibroblast growth factor 19 has a pronounced diurnal variation and modulates hepatic bile acid synthesis in man.

29 October 2018

1 reference

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Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911127

OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911127

Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

29 October 2018

1 reference

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Complementary stimulation of hepatobiliary transport and detoxification systems by rifampicin and ursodeoxycholic acid in humans

29 October 2018

1 reference

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Analysis of the in vivo functions of Mrp3.

29 October 2018

1 reference

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Multidrug resistance-associated protein 4 is up-regulated in liver but down-regulated in kidney in obstructive cholestasis in the rat.

29 October 2018

1 reference

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Targeted deletion of the ileal bile acid transporter eliminates enterohepatic cycling of bile acids in mice

29 October 2018

1 reference

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The enzymes, regulation, and genetics of bile acid synthesis

29 October 2018

1 reference

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Hepatocyte nuclear factor-1 alpha, GATA-4, and caudal related homeodomain protein Cdx2 interact functionally to modulate intestinal gene transcription. Implication for the developmental regulation of the sucrase-isomaltase gene.

29 October 2018

1 reference

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Sinusoidal efflux of taurocholate is enhanced in Mrp2-deficient rat liver

29 October 2018

1 reference

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Cellular localization and up-regulation of multidrug resistance-associated protein 3 in hepatocytes and cholangiocytes during obstructive cholestasis in rat liver

29 October 2018

1 reference

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Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911127

Carrier-mediated jejunal absorption of conjugated bile acids in the guinea pig.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911127

Failure of intravenous infusion of taurocholate to down-regulate cholesterol 7 alpha-hydroxylase in rats with biliary fistulas.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911127

Identification of a mutation in the ileal sodium-dependent bile acid transporter gene that abolishes transport activity

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911127

Compensatory role of P-glycoproteins in knockout mice lacking the bile salt export pump

29 October 2018

1 reference

12 December 2020

ATP-dependent transport of bile salts by rat multidrug resistance-associated protein 3 (Mrp3)

1 reference

12 December 2020

Characterization of inducible nature of MRP3 in rat liver

1 reference

12 December 2020

Altered bile acid metabolism in primary biliary cirrhosis

1 reference

12 December 2020

Bile Salt Sulphates in Cholestasis

1 reference

12 December 2020

[Radioactive labeling of mouse adrenal cortex for study of steroid sulfation in inner cortex zone]

1 reference

12 December 2020

Identification and comparison of bile acid-binding polypeptides in ileal basolateral membrane

1 reference

12 December 2020

Transepithelial transport of cholyltaurine by Caco-2 cell monolayers is sodium dependent

1 reference

12 December 2020

Intestinal absorption of bile acids in the rabbit: different transport rates in jejunum and ileum

1 reference

12 December 2020

RENAL EXCRETION OF BILE ACIDS: TAUROCHOLIC, GLYCOCHOLIC, AND COLIC ACIDS

1 reference

12 December 2020

Exploring possible mechanisms for primary bile acid malabsorption: evidence for different regulation of ileal bile acid transporter transcripts in chronic diarrhoea

1 reference

12 December 2020

The Caco-2 cell monolayer: usefulness and limitations

1 reference

12 December 2020

In VivoImaging of Farnesoid X Receptor Activity Reveals the Ileum as the Primary Bile Acid Signaling Tissue

1 reference

12 December 2020

10.1016/J.BBALIP.2010.06.002

Identifiers

DOI

1 reference

30 July 2017

1 reference

30 July 2017

1 reference