Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism (Q28209290)

Solute carrier organic anion transporter family, member 1a1

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Cytochrome P450, family 7, subfamily a, polypeptide 1

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ATP-binding cassette, sub-family B (MDR/TAP), member 4

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Solute carrier organic anion transporter family, member 1a4

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HNF1 homeobox A

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ATP-binding cassette, sub-family B (MDR/TAP), member 11

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Solute carrier family 10 (sodium/bile acid cotransporter family), member 1

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author name string

D Q Shih

1

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M Bussen

2

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E Sehayek

3

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M Ananthanarayanan

4

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B L Shneider

5

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F J Suchy

6

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S Shefer

7

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J S Bollileni

8

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F J Gonzalez

9

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J L Breslow

10

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M Stoffel

Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)

11

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language of work or name

English

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publication date

April 2001

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published in

Nature Genetics

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volume

27

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page(s)

375-82

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issue

4

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cites work

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7 January 2021

Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria, and renal Fanconi syndrome

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7 January 2021

Laron dwarfism and non-insulin-dependent diabetes mellitus in the Hnf-1alpha knockout mouse

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7 January 2021

The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

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7 January 2021

"Don't know much bile-ology"

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7 January 2021

Substrate specificity of sinusoidal bile acid and organic anion uptake systems in rat and human liver

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7 January 2021

Bile acid and xenobiotic transporters in liver

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7 January 2021

Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis

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7 January 2021

Regulation of bile acid synthesis

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7 January 2021

An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

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7 January 2021

Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha

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7 January 2021

Identification of a nuclear receptor for bile acids

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7 January 2021

Bile acids: natural ligands for an orphan nuclear receptor

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7 January 2021

CPF: an orphan nuclear receptor that regulates liver-specific expression of the human cholesterol 7alpha-hydroxylase gene

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7 January 2021

A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

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7 January 2021

Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

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7 January 2021

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

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7 January 2021

HNF1 activates transcription of the human gene for insulin-like growth factor binding protein-1.

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7 January 2021

Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice

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7 January 2021

Secretion of lipoprotein-X by perfused livers of rats with cholestasis

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7 January 2021

Formation of lipoprotein-X. Its relationship to bile compounds

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7 January 2021

Plasma lipoproteins in familial lecithin: cholesterol acyltransferase deficiency: physical and chemical studies of low and high density lipoproteins

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7 January 2021

The lipid bilayer structure of the abnormal human plasma lipoprotein X. An X-ray small-angle-scattering study

1 reference

7 January 2021

Small, dense low density lipoproteins, the insulin resistance syndrome and noninsulin-dependent diabetes.

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7 January 2021

Mild dyslipidemia in mice following targeted inactivation of the hepatic lipase gene

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7 January 2021

Cholesteryl ester transfer protein corrects dysfunctional high density lipoproteins and reduces aortic atherosclerosis in lecithin cholesterol acyltransferase transgenic mice

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7 January 2021

Swine lipoproteins and atherosclerosis. Changes in the plasma lipoproteins and apoproteins induced by cholesterol feeding

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7 January 2021

The maturity-onset diabetes of the young (MODY1) transcription factor HNF4alpha regulates expression of genes required for glucose transport and metabolism

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7 January 2021

HNF-1 alpha and HNF-1 beta (vHNF-1) share dimerization and homeo domains, but not activation domains, and form heterodimers in vitro

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7 January 2021

.DELTA.22-Ursodeoxycholic Acid, a Unique Metabolite of Administered Ursodeoxycholic Acid in Rats, Indicating Partial .beta.-Oxidation as a Major Pathway for Bile Acid Metabolism

1 reference

7 January 2021

Intestinal expression of human apolipoprotein A-IV in transgenic mice fails to influence dietary lipid absorption or feeding behavior

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7 January 2021

Biliary cholesterol excretion: a novel mechanism that regulates dietary cholesterol absorption

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7 January 2021

Cloning and characterization of a novel peptidase from rat and human ileum

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7 January 2021