The promise and challenge of high-throughput sequencing of the antibody repertoire. (Q33962293)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24441474%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

The promise and challenge of high-throughput sequencing of the antibody repertoire (English)

1 reference

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5 March 2020

1 reference

high-throughput sequencing

1 reference

2

1 reference

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5 March 2020

Christian E Busse

4

1 reference

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5 March 2020

6

Stephen R Quake

1 reference

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5 March 2020

author name string

George Georgiou

1

1 reference

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5 March 2020

John Beausang

3

1 reference

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5 March 2020

Hedda Wardemann

5

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5 March 2020

publication date

19 January 2014

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5 March 2020

1 reference

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5 March 2020

volume

32

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5 March 2020

issue

2

1 reference

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5 March 2020

page(s)

158-168

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https://scigraph.springernature.com/pub.10.1038/nbt.2782

5 March 2020

exact match

0 references

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5 July 2018

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Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition

5 July 2018

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5 July 2018

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5 July 2018

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Lineage structure of the human antibody repertoire in response to influenza vaccination

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Immunoglobulin G4+ clones identified by next-generation sequencing dominate the B cell receptor repertoire in immunoglobulin G4 associated cholangitis

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Application of circular consensus sequencing and network analysis to characterize the bovine IgG repertoire

5 July 2018

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Massive evolution of the immunoglobulin heavy chain locus in children with B precursor acute lymphoblastic leukemia

5 July 2018

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5 July 2018

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Origin, diversity, and maturation of human antiviral antibodies analyzed by high-throughput sequencing

5 July 2018

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5 July 2018

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5 July 2018

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Potassium channel KIR4.1 as an immune target in multiple sclerosis

5 July 2018

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Location and length distribution of somatic hypermutation-associated DNA insertions and deletions reveals regions of antibody structural plasticity

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Age, microbiota, and T cells shape diverse individual IgA repertoires in the intestine

5 July 2018

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Digital RNA sequencing minimizes sequence-dependent bias and amplification noise with optimized single-molecule barcodes

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Rep-Seq: uncovering the immunological repertoire through next-generation sequencing.

5 July 2018

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Differential regulation of self-reactivity discriminates between IgG+ human circulating memory B cells and bone marrow plasma cells

5 July 2018

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454 antibody sequencing - error characterization and correction

5 July 2018

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Antibody V(h) repertoire differences between resolving and chronically evolving hepatitis C virus infections

5 July 2018

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Epitope-specific human influenza antibody repertoires diversify by B cell intraclonal sequence divergence and interclonal convergence

5 July 2018

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Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

5 July 2018

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High-resolution description of antibody heavy-chain repertoires in humans

5 July 2018

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Addressing challenges in the production and analysis of illumina sequencing data

5 July 2018

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A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins

5 July 2018

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Divergent human populations show extensive shared IGK rearrangements in peripheral blood B cells

5 July 2018

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Vaccination-induced changes in human B-cell repertoire and pneumococcal IgM and IgA antibody at different ages.

5 July 2018

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Detection and quantification of rare mutations with massively parallel sequencing

5 July 2018

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Counting individual DNA molecules by the stochastic attachment of diverse labels

5 July 2018

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IgH gene rearrangements as plasma biomarkers in Non- Hodgkin's lymphoma patients

5 July 2018

1 reference

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Determinism and stochasticity during maturation of the zebrafish antibody repertoire

5 July 2018

1 reference

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Beyond natural antibodies: the power of in vitro display technologies

5 July 2018

1 reference

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Identification of errors introduced during high throughput sequencing of the T cell receptor repertoire

5 July 2018

1 reference

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Sequencing antibody repertoires: the next generation

5 July 2018

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Model for comparative analysis of antigen receptor repertoires

5 July 2018

1 reference

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Clustering-based identification of clonally-related immunoglobulin gene sequence sets

5 July 2018

1 reference

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Antigen receptor allelic exclusion: an update and reappraisal

5 July 2018

1 reference

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By-passing in vitro screening--next generation sequencing technologies applied to antibody display and in silico candidate selection

5 July 2018

1 reference

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The human immune response to Dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Regulation of the B cell receptor repertoire and self-reactivity by BAFF

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Monoclonal antibodies isolated without screening by analyzing the variable-gene repertoire of plasma cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Individual variation in the germline Ig gene repertoire inferred from variable region gene rearrangements.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

High-throughput immunoglobulin repertoire analysis distinguishes between human IgM memory and switched memory B-cell populations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Therapeutic antibodies for autoimmunity and inflammation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Maximum entropy models for antibody diversity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Rapid construction and characterization of synthetic antibody libraries without DNA amplification

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Measurement and clinical monitoring of human lymphocyte clonality by massively parallel VDJ pyrosequencing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

High-throughput sequencing of the zebrafish antibody repertoire

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

B-cell tolerance checkpoints in health and autoimmunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Rapid cloning of high-affinity human monoclonal antibodies against influenza virus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Autoreactivity in human IgG+ memory B cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

VH replacement in mice and humans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Forced usage of positively charged amino acids in immunoglobulin CDR-H3 impairs B cell development and antibody production

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Prevalence of monoclonal gammopathy of undetermined significance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Isolation of human antibody repertoires with preservation of the natural heavy and light chain pairing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Expressed murine and human CDR-H3 intervals of equal length exhibit distinct repertoires that differ in their amino acid composition and predicted range of structures

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Predominant autoantibody production by early human B cell precursors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Human immunoglobulin (Ig)M+IgD+ peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Variable region sequences of five human immunoglobulin heavy chains of the VH3 subgroup: definitive identification of four heavy chain hypervariable regions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Early restriction of the human antibody repertoire.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Single-cell based high-throughput sequencing of full-length immunoglobulin heavy and light chain genes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Broadly neutralizing antibodies and the search for an HIV-1 vaccine: the end of the beginning

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Clues to pathogenesis of Waldenström macroglobulinemia and immunoglobulin M monoclonal gammopathy of undetermined significance provided by analysis of immunoglobulin heavy chain gene rearrangement and clustering of B-cell receptors.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Atypical and classical memory B cells produce Plasmodium falciparum neutralizing antibodies.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Wrestling with the repertoire: the promise and perils of next generation sequencing for antigen receptors

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Shaping of human germline IgH repertoires revealed by deep sequencing

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

High-throughput antibody sequencing reveals genetic evidence of global regulation of the naïve and memory repertoires that extends across individuals.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Frequency and genetic characterization of V(DD)J recombinants in the human peripheral blood antibody repertoire.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

The inference of phased haplotypes for the immunoglobulin H chain V region gene loci by analysis of VDJ gene rearrangements.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Targeting TLRs expands the antibody repertoire in response to a malaria vaccine.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

IgE sequences in individuals living in an area of endemic parasitism show little mutational evidence of antigen selection.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Genomic screening by 454 pyrosequencing identifies a new human IGHV gene and sixteen other new IGHV allelic variants.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

NCBI GEO standards and services for microarray data.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Diversity in the CDR3 region of V(H) is sufficient for most antibody specificities

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Evidence for a large compartment of IgM-expressing memory B cells in humans.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Analysis of the B-cell progenitor compartment at the level of single cells.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Limiting dilution analysis of the B cell compartment in human bone marrow

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113560

Proteomics-directed cloning of circulating antiviral human monoclonal antibodies

29 October 2018

1 reference

12 December 2020

Fundamental characteristics of the immunoglobulin VH repertoire of chickens in comparison with those of humans, mice, and camelids

1 reference

12 December 2020

A proteomics approach for the identification and cloning of monoclonal antibodies from serum

1 reference

12 December 2020

History of immunology

1 reference

12 December 2020

High-throughput multiplex sequencing of miRNA

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNBT.2782

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NBT.2782

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24441474%20AND%20SRC:MED&resulttype=core&format=json

release_cyzfdhu6urbxfg4amo6eme2odi

5 March 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/cyzfdhu6urbxfg4amo6eme2odi

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24441474%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24441474%20AND%20SRC:MED&resulttype=core&format=json