High abundance of plasma cells secreting transglutaminase 2-specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions. (Q42462128)

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scientific article published on 26 February 2012

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English	High abundance of plasma cells secreting transglutaminase 2-specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions.	scientific article published on 26 February 2012

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24 January 2020

High abundance of plasma cells secreting transglutaminase 2-specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions (English)

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24 January 2020

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Roberto Di Niro

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Luka Mesin

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Nai-Ying Zheng

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24 January 2020

Jorunn Stamnaes

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24 January 2020

Michael Morrissey

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24 January 2020

Jane-Hwei Lee

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24 January 2020

Min Huang

7

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24 January 2020

M Fleur du Pré

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24 January 2020

Knut E A Lundin

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24 January 2020

Patrick C Wilson

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24 January 2020

Ludvig M Sollid

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26 February 2012

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24 January 2020

Nature Medicine

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3

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24 January 2020

441-445

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24 January 2020

https://scigraph.springernature.com/pub.10.1038/nm.2656

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The majority of intestinal IgA+ and IgG+ plasmablasts in the human gut are antigen-specific

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28 May 2018

Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter

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Control systems and decision making for antibody production.

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28 May 2018

Reversible microbial colonization of germ-free mice reveals the dynamics of IgA immune responses

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28 May 2018

Taking advantage: high-affinity B cells in the germinal center have lower death rates, but similar rates of division, compared to low-affinity cells

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Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

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Rapid generation of fully human monoclonal antibodies specific to a vaccinating antigen

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Functional anergy in a subpopulation of naive B cells from healthy humans that express autoreactive immunoglobulin receptors.

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B-cell tolerance checkpoints in health and autoimmunity

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28 May 2018

The propensity for deamidation and transamidation of peptides by transglutaminase 2 is dependent on substrate affinity and reaction conditions

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28 May 2018

Nature and functions of autoantibodies

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28 May 2018

Rapid cloning of high-affinity human monoclonal antibodies against influenza virus

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28 May 2018

Mature B cells class switched to IgD are autoreactive in healthy individuals

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28 May 2018

Autoreactivity in human IgG+ memory B cells

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28 May 2018

Competence and competition: the challenge of becoming a long-lived plasma cell

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28 May 2018

Endomysial antibody-negative coeliac disease: clinical characteristics and intestinal autoantibody deposits

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28 May 2018

Cross linking to tissue transglutaminase and collagen favours gliadin toxicity in coeliac disease

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28 May 2018

The many faces of celiac disease: clinical presentation of celiac disease in the adult population

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28 May 2018

The diagnostic accuracy of serologic tests for celiac disease: a systematic review

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28 May 2018

Extrafollicular antibody responses

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28 May 2018

Coeliac disease: dissecting a complex inflammatory disorder

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28 May 2018

Anti-tissue transglutaminase antibodies from coeliac patients inhibit transglutaminase activity both in vitro and in situ

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28 May 2018

Molecular dissection of the tissue transglutaminase autoantibody response in celiac disease.

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28 May 2018

Affinity dependence of the B cell response to antigen: a threshold, a ceiling, and the importance of off-rate

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28 May 2018

Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease.

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28 May 2018

Autoantibodies in coeliac disease: tissue transglutaminase--guilt by association?

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28 May 2018

Identification of tissue transglutaminase as the autoantigen of celiac disease

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28 May 2018

Antigen-induced B-cell death and elimination during germinal-centre immune responses

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28 May 2018

Developmental regulation of IgM secretion: the role of the carboxy-terminal cysteine

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28 May 2018

Association of subepithelial deposition of activated complement and immunoglobulin G and M response to gluten in celiac disease

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28 May 2018

Stimulation of mouse lymphocytes by insoluble anti-mouse immunoglobulin

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28 May 2018

Posttranslational modification of gluten shapes TCR usage in celiac disease.

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16 August 2018

Long-lived plasma cells from human small intestine biopsies secrete immunoglobulins for many weeks in vitro.

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Antigen affinity controls rapid T-dependent antibody production by driving the expansion rather than the differentiation or extrafollicular migration of early plasmablasts.

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Blood-borne human plasma cells in steady state are derived from mucosal immune responses

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Low-level hypermutation in T cell-independent germinal centers compared with high mutation rates associated with T cell-dependent germinal centers

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Characteristics of IgVH genes used by human intestinal plasma cells from childhood.

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12 December 2020

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High density of intraepithelial gammadelta lymphocytes and deposits of immunoglobulin (Ig)M anti-tissue transglutaminase antibodies in the jejunum of coeliac patients with IgA deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/22366952

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue transglutaminase autoantibody enzyme-linked immunosorbent assay in detecting celiac disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22366952

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A major peritoneal reservoir of precursors for intestinal IgA plasma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22366952

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Celiac disease without villous atrophy in children: a prospective study

1 reference

https://pubmed.ncbi.nlm.nih.gov/22366952

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective deamidation by tissue transglutaminase strongly enhances gliadin-specific T cell reactivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22366952

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Screening detects a high proportion of celiac disease in young HLA-genotyped children

1 reference

https://pubmed.ncbi.nlm.nih.gov/22366952

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/NM.2656

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24 January 2020

1 reference

Europe PubMed Central

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24 January 2020

1 reference

Europe PubMed Central

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24 January 2020

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