Reshaping Antibody Diversity (Q27678538)

12

object named as

Peter G Schultz

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author name string

Feng Wang

1

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Damian C Ekiert

2

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Insha Ahmad

3

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Wenli Yu

4

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Yong Zhang

5

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Omar Bazirgan

6

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Ali Torkamani

7

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Terje Raudsepp

8

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Waithaka Mwangi

9

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Michael F Criscitiello

10

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Vaughn V Smider

Somatic hypermutation maintains antibody thermodynamic stability during affinity maturation

13

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language of work or name

English

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publication date

6 June 2013

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published in

Cell

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volume

153

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issue

6

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page(s)

1379-93

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007204

Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1

20 March 2017

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20 March 2017

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MolProbity: all-atom structure validation for macromolecular crystallography

20 March 2017

1 reference

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The genome sequence of taurine cattle: a window to ruminant biology and evolution

20 March 2017

1 reference

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Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007204

Diversity and Function of Adaptive Immune Receptors in a Jawless Vertebrate

20 March 2017

1 reference

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Natural beta-sheet proteins use negative design to avoid edge-to-edge aggregation

20 March 2017

1 reference

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Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design

20 March 2017

1 reference

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A single-domain antibody fragment in complex with RNase A: non-canonical loop structures and nanomolar affinity using two CDR loops

20 March 2017

1 reference

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Features and development of Coot

20 March 2017

1 reference

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Phasercrystallographic software

20 March 2017

1 reference

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The RAG proteins and V(D)J recombination: complexes, ends, and transposition

20 March 2017

1 reference

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Crystal structure of a shark single-domain antibody V region in complex with lysozyme

20 March 2017

1 reference

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The end-joining reaction in V(D)J recombination

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007204

Unique scorpion toxin with a putative ancestral fold provides insight into evolution of the inhibitor cystine knot motif

20 March 2017

1 reference

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An evolutionary view of the mechanism for immune and genome diversity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007204

Characterization of a high-affinity human antibody with a disulfide bridge in the third complementarity-determining region of the heavy chain.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007204

Engineering knottins as novel binding agents

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007204

Structure and modeling of knottins, a promising molecular scaffold for drug discovery

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007204

Spatially addressed combinatorial protein libraries for recombinant antibody discovery and optimization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007204

Biological diversity and therapeutic potential of natural and engineered cystine knot miniproteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007204

HIV-1 and influenza antibodies: seeing antigens in new ways

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007204

Molecular mechanisms of antibody somatic hypermutation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007204

Multivalent avimer proteins evolved by exon shuffling of a family of human receptor domains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007204

The bovine antibody repertoire

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007204

Somatic diversification of variable lymphocyte receptors in the agnathan sea lamprey

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007204

Uncleaved NS2-3 is required for production of infectious bovine viral diarrhea virus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007204

Analysis of the antigen combining site: correlations between length and sequence composition of the hypervariable loops and the nature of the antigen

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007204

The cystine knot motif in toxins and implications for drug design.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007204

Construction and characterization of a bovine bacterial artificial chromosome library

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007204

Stepwise intraclonal maturation of antibody affinity through somatic hypermutation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007204

Bovine IgM antibodies with exceptionally long complementarity-determining region 3 of the heavy chain share unique structural properties conferring restricted VH + Vlambda pairings.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007204

Bovine IgG repertoire is dominated by a single diversified VH gene family.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007204

Use of a single VH family and long CDR3s in the variable region of cattle Ig heavy chains.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007204

CD205 antigen targeting combined with dendritic cell recruitment factors and antigen-linked CD40L activation primes and expands significant antigen-specific antibody and CD4(+) T cell responses following DNA vaccination of outbred animals.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007204

FISH for mapping single copy genes.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007204

Duplicated copies of the bovine JH locus contribute to the Ig repertoire

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007204

International System for Chromosome Nomenclature of Domestic Bovids (ISCNDB 2000).

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007204

Exceptionally long CDR3H region with multiple cysteine residues in functional bovine IgM antibodies

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007204

A single VH family and long CDR3s are the targets for hypermutation in bovine immunoglobulin heavy chains

27 November 2018

1 reference

12 December 2020

Organization of D(H)-gene locus is distinct in cattle

1 reference

12 December 2020

Gene conversion contributes to Ig light chain diversity in cattle

1 reference

12 December 2020

Novel atypical nucleotide insertions specifically at VH-DH junction generate exceptionally long CDR3H in cattle antibodies

1 reference

12 December 2020

10.1016/J.CELL.2013.04.049

Identifiers

DOI

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2600689

2600689

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1 reference

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