Identification of novel therapeutic targets in the PI3K/AKT/mTOR pathway in hepatocellular carcinoma using targeted next generation sequencing (Q33917547)

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Language	Label	Description	Also known as
English	Identification of novel therapeutic targets in the PI3K/AKT/mTOR pathway in hepatocellular carcinoma using targeted next generation sequencing	scientific article

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scholarly article

1 reference

Europe PubMed Central

30 July 2017

Identification of novel therapeutic targets in the PI3K/AKT/mTOR pathway in hepatocellular carcinoma using targeted next generation sequencing (English)

1 reference

Europe PubMed Central

30 July 2017

hepatocellular carcinoma

1 reference

based on heuristic

inferred from title

Razelle Kurzrock

5

object named as

Razelle Kurzrock

1 reference

Europe PubMed Central

30 July 2017

Apostolia Maria Tsimberidou

3

object named as

Apostolia M Tsimberidou

1 reference

Europe PubMed Central

30 July 2017

1

object named as

Filip Janku

1 reference

Europe PubMed Central

30 July 2017

author name string

Ahmed O Kaseb

2

1 reference

Europe PubMed Central

30 July 2017

Robert A Wolff

4

1 reference

Europe PubMed Central

30 July 2017

language of work or name

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publication date

1 May 2014

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

5

1 reference

Europe PubMed Central

30 July 2017

10

1 reference

Europe PubMed Central

30 July 2017

3012-3022

1 reference

Europe PubMed Central

30 July 2017

The AKT inhibitor MK-2206 is cytotoxic in hepatocarcinoma cells displaying hyperphosphorylated AKT-1 and synergizes with conventional chemotherapy

1 reference

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5 July 2018

Functional analysis of non-hotspot AKT1 mutants found in human breast cancers identifies novel driver mutations: implications for personalized medicine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102787

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Elucidating distinct roles for NF1 in melanomagenesis

1 reference

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5 July 2018

PIK3CA mutation H1047R is associated with response to PI3K/AKT/mTOR signaling pathway inhibitors in early-phase clinical trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102787

5 July 2018

Glyceraldehyde-3-phosphate dehydrogenase: a promising target for molecular therapy in hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102787

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Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial.

1 reference

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The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102787

5 July 2018

Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102787

5 July 2018

mTOR inhibitors synergize on regression, reversal of gene expression, and autophagy in hepatocellular carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102787

5 July 2018

Targeted therapy for hepatocellular carcinoma: novel agents on the horizon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102787

5 July 2018

Alterations of TP53 are associated with a poor outcome for patients with hepatocellular carcinoma: evidence from a systematic review and meta-analysis

1 reference

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Targeting MET in cancer: rationale and progress

1 reference

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5 July 2018

Will PI3K pathway inhibitors be effective as single agents in patients with cancer?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102787

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MET amplification identifies a small and aggressive subgroup of esophagogastric adenocarcinoma with evidence of responsiveness to crizotinib

1 reference

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Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102787

5 July 2018

Hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102787

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Identification and evaluation of a potent novel ATR inhibitor, NU6027, in breast and ovarian cancer cell lines

1 reference

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Exploiting the homologous recombination DNA repair network for targeted cancer therapy

1 reference

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Phase 1/2 study of everolimus in advanced hepatocellular carcinoma

1 reference

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5 July 2018

High-resolution characterization of a hepatocellular carcinoma genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102787

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Elevated expression of CDK4 in lung cancer

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FGF19 as a postprandial, insulin-independent activator of hepatic protein and glycogen synthesis

1 reference

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Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7.

1 reference

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5 July 2018

Targeting the PI3K/Akt/mTOR pathway--beyond rapalogs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102787

5 July 2018

PIK3CA mutations in patients with advanced cancers treated with PI3K/AKT/mTOR axis inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102787

5 July 2018

Activating mutations of TOR (target of rapamycin).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102787

5 July 2018

mTOR signaling is activated by FLT3 kinase and promotes survival of FLT3-mutated acute myeloid leukemia cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102787

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Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102787

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COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

1 reference

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ARID1A mutations in endometriosis-associated ovarian carcinomas

1 reference

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An alternative splicing network links cell-cycle control to apoptosis

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1 reference

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Interactions between MDM2 and TP53 Genetic Alterations, and Their Impact on Response to MDM2 Inhibitors and Other Chemotherapeutic Drugs in Cancer Cells.

1 reference

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The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers

1 reference

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1 reference

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Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers

1 reference

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BRCA1-associated protein-1 is a tumor suppressor that requires deubiquitinating activity and nuclear localization

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Structural biology of the tumor suppressor p53.

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10.18632/ONCOTARGET.1687

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24 November 2022

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Europe PubMed Central

30 July 2017

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Europe PubMed Central

30 July 2017

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