Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma (Q37284612)

19 August 2017

Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma (English)

1 reference

19 August 2017

18

Jessica Zucman-Rossi

0 references

Paulette Bioulac-Sage

8

Paulette Bioulac-Sage

0 references

Yannick Ladeiro

Yannick Ladeiro

4

0 references

Eric Letouzé

Eric Letouzé

16

0 references

Sandrine Imbeaud

Sandrine Imbeaud

3

0 references

Alexis Laurent

Alexis Laurent

14

0 references

author name string

Cécile Guichard

1

1 reference

19 August 2017

Giuliana Amaddeo

2

1 reference

19 August 2017

Laura Pelletier

5

1 reference

19 August 2017

Ichrafe Ben Maad

6

1 reference

19 August 2017

Julien Calderaro

7

1 reference

19 August 2017

Mélanie Letexier

9

1 reference

19 August 2017

Françoise Degos

10

1 reference

19 August 2017

Bruno Clément

11

1 reference

19 August 2017

Charles Balabaud

12

1 reference

19 August 2017

Eric Chevet

13

1 reference

19 August 2017

Gabrielle Couchy

15

1 reference

19 August 2017

Fabien Calvo

17

1 reference

19 August 2017

language of work or name

English

0 references

publication date

6 May 2012

1 reference

19 August 2017

1 reference

19 August 2017

44

1 reference

19 August 2017

694-698

1 reference

19 August 2017

6

1 reference

https://scigraph.springernature.com/pub.10.1038/ng.2256

19 August 2017

0 references

cites work

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Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3819251

ARID1A, a factor that promotes formation of SWI/SNF-mediated chromatin remodeling, is a tumor suppressor in gynecologic cancers

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3819251

Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3819251

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

6 September 2017

1 reference

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SWI/SNF nucleosome remodellers and cancer.

6 September 2017

1 reference

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Genetics of hepatobiliary carcinogenesis

6 September 2017

1 reference

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Identification of a therapeutic strategy targeting amplified FGF19 in liver cancer by Oncogenomic screening

6 September 2017

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Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

6 September 2017

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ARID1A mutations in endometriosis-associated ovarian carcinomas

6 September 2017

1 reference

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Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma

6 September 2017

1 reference

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Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours

6 September 2017

1 reference

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6 September 2017

1 reference

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The IRF family transcription factors in immunity and oncogenesis

6 September 2017

1 reference

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Hepatocellular carcinoma: epidemiology and molecular carcinogenesis

6 September 2017

1 reference

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Patterns of somatic mutation in human cancer genomes

6 September 2017

1 reference

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Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets

6 September 2017

1 reference

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Bi-allelic inactivation of TCF1 in hepatic adenomas

6 September 2017

1 reference

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Frequent k- ras -2 mutations and p16(INK4A)methylation in hepatocellular carcinomas in workers exposed to vinyl chloride

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3819251

Patterns of p53 G-->T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke

6 September 2017

1 reference

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Regulation of IRF2 transcriptional activity by its sumoylation

6 September 2017

1 reference

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Mutational hot spot in the p53 gene in human hepatocellular carcinomas

14 September 2017

1 reference

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Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa

26 June 2018

1 reference

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Altered ERK/MAPK signaling in the hippocampus of the mrsk2_KO mouse model of Coffin-Lowry syndrome.

26 June 2018

1 reference

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Oncogenic NRF2 mutations in squamous cell carcinomas of oesophagus and skin

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3819251

Slow repair of bulky DNA adducts along the nontranscribed strand of the human p53 gene may explain the strand bias of transversion mutations in cancers.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3819251

Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data

3 September 2018

1 reference

High-resolution characterization of a hepatocellular carcinoma genome

21 January 2018

1 reference

Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing

21 January 2018

1 reference

A method and server for predicting damaging missense mutations

21 January 2018

1 reference

Integrative genomics viewer

21 January 2018

1 reference

High-resolution genomic profiling of chromosomal aberrations using Infinium whole-genome genotyping

21 January 2018

1 reference

Normalization of Illumina Infinium whole-genome SNP data improves copy number estimates and allelic intensity ratios

21 January 2018

1 reference

Genome Alteration Print (GAP): a tool to visualize and mine complex cancer genomic profiles obtained by SNP arrays

21 January 2018

1 reference

The landscape of somatic copy-number alteration across human cancers

21 January 2018

1 reference

A systems biology approach for pathway level analysis

21 January 2018

1 reference

R spider: a network-based analysis of gene lists by combining signaling and metabolic pathways from Reactome and KEGG databases

21 January 2018

1 reference

HNF1alpha inactivation promotes lipogenesis in human hepatocellular adenoma independently of SREBP-1 and carbohydrate-response element-binding protein (ChREBP) activation

21 January 2018

1 reference

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

1 reference

EGF induced SOS phosphorylation in PC12 cells involves P90 RSK-2

21 January 2018

1 reference

Role of Mdm2 acid domain interactions in recognition and ubiquitination of the transcription factor IRF-2

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22561517

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NG.2256

1 reference

Dimensions Publication ID

19 August 2017

0 references

1 reference

19 August 2017

1 reference