The saponins: polar isoprenoids with important and diverse biological activities (Q33902446)

29 July 2017

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title

The saponins: polar isoprenoids with important and diverse biological activities (English)

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29 July 2017

2

Rebecca J M Goss

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author name string

Anne Osbourn

series ordinal

1

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PubMed ID

21584304

29 July 2017

Rebecca J M Goss

series ordinal

2

1 reference

PubMed ID

21584304

29 July 2017

Robert A Field

series ordinal

3

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29 July 2017

16 May 2011

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29 July 2017

Natural Product Reports

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29 July 2017

28

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29 July 2017

7

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29 July 2017

1261-1268

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Biosynthetic diversity in plant triterpene cyclization

29 July 2017

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Saponins, classification and occurrence in the plant kingdom

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Production of plant bioactive triterpenoid saponins: elicitation strategies and target genes to improve yields.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Two new steroidal compounds from starfish Asterias amurensis Lutken

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Cytotoxic asterosaponins capable of promoting polymerization of tubulin from the starfish Culcita novaeguineae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Qualitative and quantitative saponin contents in five sea cucumbers from the Indian ocean

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

The genetics and molecular genetics of terpene and sterol origami

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Compromised disease resistance in saponin-deficient plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

A saponin-detoxifying enzyme mediates suppression of plant defences

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Tomatidine and lycotetraose, hydrolysis products of alpha-tomatine by Fusarium oxysporum tomatinase, suppress induced defense responses in tomato cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Plant-microbe interactions: chemical diversity in plant defense.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Identification of defense compounds in Barbarea vulgaris against the herbivore Phyllotreta nemorum by an ecometabolomic approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Legume natural products: understanding and manipulating complex pathways for human and animal health

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Tomato glycoalkaloids: role in the plant and in the diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Potato glycoalkaloids: true safety or false sense of security?

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Potato glycoalkaloids and metabolites: roles in the plant and in the diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Dual effects of plant steroidal alkaloids on Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Proteomic and transcriptomic study on the action of a cytotoxic saponin (Polyphyllin D): induction of endoplasmic reticulum stress and mitochondria-mediated apoptotic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Soapwort saponins trigger clathrin-mediated endocytosis of saporin, a type I ribosome-inactivating protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Pentacyclic triterpenoids and their saponins with apoptosis-inducing activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Saponins as cytotoxic agents: a review.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Avicin D, a plant triterpenoid, induces cell apoptosis by recruitment of Fas and downstream signaling molecules into lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Ginsenoside Rh2 induces ligand-independent Fas activation via lipid raft disruption.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

The cadherin-catenin adhesion system in signaling and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Lupeol, a novel anti-inflammatory and anti-cancer dietary triterpene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Role of lupeol synthase in Lotus japonicus nodule formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

TGR5: an emerging bile acid G-protein-coupled receptor target for the potential treatment of metabolic disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Chromosaponin I specifically interacts with AUX1 protein in regulating the gravitropic response of Arabidopsis roots

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Sad3 and sad4 are required for saponin biosynthesis and root development in oat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Current synthesis of triterpene saponins

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Synthesis of QS-21-xylose: establishment of the immunopotentiating activity of synthetic QS-21 adjuvant with a melanoma vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Synthesis and structure verification of the vaccine adjuvant QS-7-Api. Synthetic access to homogeneous Quillaja saponaria immunostimulants

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Synthetic studies of complex immunostimulants from Quillaja saponaria: synthesis of the potent clinical immunoadjuvant QS-21Aapi.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Synthesis of the potent immunostimulatory adjuvant QS-21A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Advances in saponin-based adjuvants

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Preclinical evaluation of the synthetic adjuvant SQS-21 and its constituent isomeric saponins

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Design and synthesis of potent Quillaja saponin vaccine adjuvants

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Amplified immune response by ginsenoside-based nanoparticles (ginsomes).

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Antimicrobial natural products: an update on future antibiotic drug candidates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Plant-derived triterpenoids and analogues as antitumor and anti-HIV agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Chemical study and medical application of saponins as anti-cancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Enzymatic synthesis of cyclic triterpenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

An oxidosqualene cyclase makes numerous products by diverse mechanisms: a challenge to prevailing concepts of triterpene biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Licorice beta-amyrin 11-oxidase, a cytochrome P450 with a key role in the biosynthesis of the triterpene sweetener glycyrrhizin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

A different function for a member of an ancient and highly conserved cytochrome P450 family: from essential sterols to plant defense.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

High throughput screening of mutants of oat that are defective in triterpene synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Insights into the function and evolution of P450s in plant steroid metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Identification of beta-amyrin and sophoradiol 24-hydroxylase by expressed sequence tag mining and functional expression assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Metabolic diversification--independent assembly of operon-like gene clusters in different plants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Genomic and coexpression analyses predict multiple genes involved in triterpene saponin biosynthesis in Medicago truncatula

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Genomics-based selection and functional characterization of triterpene glycosyltransferases from the model legume Medicago truncatula

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Methyl jasmonate and yeast elicitor induce differential transcriptional and metabolic re-programming in cell suspension cultures of the model legume Medicago truncatula.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Characterization and engineering of glycosyltransferases responsible for steroid saponin biosynthesis in Solanaceous plants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Acyltransferases in plants: a good time to be BAHD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Cloning of the SNG1 gene of Arabidopsis reveals a role for a serine carboxypeptidase-like protein as an acyltransferase in secondary metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

An acyltransferase catalyzing the formation of diacylglucose is a serine carboxypeptidase-like protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

The sng2 mutant of Arabidopsis is defective in the gene encoding the serine carboxypeptidase-like protein sinapoylglucose:choline sinapoyltransferase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

The genes BnSCT1 and BnSCT2 from Brassica napus encoding the final enzyme of sinapine biosynthesis: molecular characterization and suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

A serine carboxypeptidase-like acyltransferase is required for synthesis of antimicrobial compounds and disease resistance in oats

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Secondary metabolic gene clusters: evolutionary toolkits for chemical innovation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Production of the antimalarial drug precursor artemisinic acid in engineered yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Discovery and development of natural product-derived chemotherapeutic agents based on a medicinal chemistry approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Natural products as inspiration for the development of asymmetric catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

A predictably selective aliphatic C-H oxidation reaction for complex molecule synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Total synthesis of eudesmane terpenes by site-selective C-H oxidations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Biologically inspired oxidation catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Chemo-enzymatic fluorination of unactivated organic compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Fluorine in pharmaceuticals: looking beyond intuition

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Engineering fluorometabolite production: fluorinase expression in Salinispora tropica Yields Fluorosalinosporamide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Integrating carbon-halogen bond formation into medicinal plant metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

Gene expression enabling synthetic diversification of natural products: chemogenetic generation of pacidamycin analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00015B

21 January 2018

Identifiers

DOI

10.1039/C1NP00015B

1 reference

29 July 2017

1 reference

PubMed ID

21584304