Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer. (Q36796876)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17446857%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

review article

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title

Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer (English)

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29 December 2019

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1

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29 December 2019

author name string

Mark M Yore

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17446857%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Michael B Sporn

series ordinal

3

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29 December 2019

language of work or name

English

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publication date

19 April 2007

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29 December 2019

published in

Nature Reviews Cancer

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29 December 2019

volume

7

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29 December 2019

page(s)

357-369

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29 December 2019

issue

5

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https://scigraph.springernature.com/pub.10.1038/nrc2129

29 December 2019

exact match

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31 March 2020

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Synthetic triterpenoids activate a pathway for apoptosis in AML cells involving downregulation of FLIP and sensitization to TRAIL.

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The novel triterpenoid CDDO-Me suppresses MAPK pathways and promotes p38 activation in acute myeloid leukemia cells

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31 March 2020

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31 March 2020

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31 March 2020

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The synthetic triterpenoid 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole blocks nuclear factor-kappaB activation through direct inhibition of IkappaB kinase beta

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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15-deoxy-Delta12,14-prostaglandin J2 as a potential endogenous regulator of redox-sensitive transcription factors

31 March 2020

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Avicins, a family of triterpenoid saponins from Acacia victoriae (Bentham), inhibit activation of nuclear factor-kappaB by inhibiting both its nuclear localization and ability to bind DNA

31 March 2020

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Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis

31 March 2020

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Celastrol, a triterpene extracted from the Chinese "Thunder of God Vine," is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice

31 March 2020

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Prospects for plant-derived chemopreventive agents exhibiting multiple mechanisms of action

31 March 2020

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31 March 2020

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Nuclear receptor that identifies a novel retinoic acid response pathway

31 March 2020

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A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR

31 March 2020

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9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

31 March 2020

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Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists

31 March 2020

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The RXR heterodimers and orphan receptors

31 March 2020

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Nuclear receptors and lipid physiology: opening the X-files

31 March 2020

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Chemoprevention: an essential approach to controlling cancer

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Retinoid x receptor heterodimers in the metabolic syndrome

31 March 2020

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31 March 2020

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Effects of rexinoids on thyrotrope function and the hypothalamic-pituitary-thyroid axis

31 March 2020

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Bexarotene: a clinical review

31 March 2020

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Design and synthesis of potent retinoid X receptor selective ligands that induce apoptosis in leukemia cells

31 March 2020

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31 March 2020

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Novel (2E,4E,6Z)-7-(2-alkoxy-3,5-dialkylbenzene)-3-methylocta-2,4,6-trienoic acid retinoid X receptor modulators are active in models of type 2 diabetes

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Identification of biomarkers modulated by the rexinoid LGD1069 (bexarotene) in human breast cells using oligonucleotide arrays

31 March 2020

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31 March 2020

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31 March 2020

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Effect of the retinoid X receptor-selective ligand LGD1069 on mammary carcinoma after tamoxifen failure

31 March 2020

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31 March 2020

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31 March 2020

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The combination of the rexinoid, LG100268, and a selective estrogen receptor modulator, either arzoxifene or acolbifene, synergizes in the prevention and treatment of mammary tumors in an estrogen receptor-negative model of breast cancer

31 March 2020

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The retinoid X receptor agonist bexarotene (Targretin) synergistically enhances the growth inhibitory activity of cytotoxic drugs in non-small cell lung cancer cells

31 March 2020

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A selective retinoid X receptor agonist bexarotene (LGD1069, targretin) inhibits angiogenesis and metastasis in solid tumours

31 March 2020

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Prevention of mouse lung tumors by targretin.

31 March 2020

1 reference

A selective retinoid X receptor agonist bexarotene (LGD1069, Targretin) prevents and overcomes multidrug resistance in advanced prostate cancer

31 March 2020

1 reference

Coregulator function: a key to understanding tissue specificity of selective receptor modulators

31 March 2020

1 reference

The selective retinoid X receptor agonist bexarotene (LGD1069, Targretin) prevents and overcomes multidrug resistance in advanced breast carcinoma

31 March 2020

1 reference

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway

31 March 2020

1 reference

Olive fruit extracts inhibit proliferation and induce apoptosis in HT-29 human colon cancer cells

31 March 2020

1 reference

A synthetic triterpenoid selectively inhibits the induction of matrix metalloproteinases 1 and 13 by inflammatory cytokines

31 March 2020

1 reference

The triterpenoid CDDO inhibits expression of matrix metalloproteinase-1, matrix metalloproteinase-13 and Bcl-3 in primary human chondrocytes

31 March 2020

1 reference

Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes.

31 March 2020

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Inflammation in atherosclerosis

31 March 2020

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Mast cells in autoimmune disease

31 March 2020

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Inflammation and therapeutic vaccination in CNS diseases

31 March 2020

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The immunopathogenesis of sepsis

31 March 2020

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Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice

31 March 2020

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Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice

31 March 2020

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Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis

31 March 2020

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In vivo modulation of the Parkinsonian phenotype by Nrf2.

31 March 2020

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Design, synthesis, and anti-inflammatory activity both in vitro and in vivo of new betulinic acid analogues having an enone functionality in ring A

31 March 2020

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2-Cyano-3,12-dioxoolean-1,9-dien-28-oic acid and related compounds inhibit growth of colon cancer cells through peroxisome proliferator-activated receptor gamma-dependent and -independent pathways

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRC2129

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17446857%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference