HFE gene variants, iron, and lipids: a novel connection in Alzheimer's disease (Q33861622)

29 July 2017

HFE gene variants, iron, and lipids: a novel connection in Alzheimer's disease (English)

1 reference

29 July 2017

0 references

0 references

Fatima Ali-Rahmani

1

1 reference

PubMed ID

25071582

29 July 2017

Cara-Lynne Schengrund

series ordinal

2

1 reference

PubMed ID

25071582

29 July 2017

James R Connor

series ordinal

3

1 reference

29 July 2017

8 July 2014

1 reference

Frontiers in Pharmacology

29 July 2017

1 reference

29 July 2017

5

1 reference

29 July 2017

165

1 reference

Plasma phospholipids identify antecedent memory impairment in older adults.

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

C282Y-HFE gene variant affects cholesterol metabolism in human neuroblastoma cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Alzheimer disease in the United States (2010-2050) estimated using the 2010 census

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Serum cholesterol and nigrostriatal R2* values in Parkinson's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

The role of iron as a mediator of oxidative stress in Alzheimer disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

The role of APP proteolytic processing in lipid metabolism.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

The role of metallobiology and amyloid-β peptides in Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Eukaryotic DNA polymerases require an iron-sulfur cluster for the formation of active complexes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Oxidative stress and β-amyloid protein in Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Mutant HFE H63D protein is associated with prolonged endoplasmic reticulum stress and increased neuronal vulnerability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Effect of HFE variants on sphingolipid expression by SH-SY5Y human neuroblastoma cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Dysregulation of sphingolipid metabolism in cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

The H63D HFE gene variant promotes activation of the intrinsic apoptotic pathway via mitochondria dysfunction following β-amyloid peptide exposure

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Impact of hemochromatosis gene (HFE) mutations on epithelial ovarian cancer risk and prognosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

The effects of cholesterol on learning and memory.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Roles for dysfunctional sphingolipid metabolism in Alzheimer's disease neuropathogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Lipid rafts: keys to neurodegeneration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Alterations in the red blood cell membrane proteome in alzheimer's subjects reflect disease-related changes and provide insight into altered cell morphology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Prevalent iron metabolism gene variants associated with increased brain ferritin iron in healthy older men.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Sphingosine kinase: Role in regulation of bioactive sphingolipid mediators in inflammation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

HFE C282Y homozygotes are at increased risk of breast and colorectal cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Prolyl-peptidyl isomerase, Pin1, phosphorylation is compromised in association with the expression of the HFE polymorphic allele, H63D.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

24S-hydroxycholesterol effects on lipid metabolism genes are modeled in traumatic brain injury

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Suggestive synergy between genetic variants in TF and HFE as risk factors for Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Alzheimer's disease as homeostatic responses to age-related myelin breakdown

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Expression of the HFE allelic variant H63D in SH-SY5Y cells affects tau phosphorylation at serine residues

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Quantitative MR phase-corrected imaging to investigate increased brain iron deposition of patients with Alzheimer disease.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

HFE polymorphisms affect cellular glutamate regulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Influence of HFE variants and cellular iron on monocyte chemoattractant protein-1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

MCP-1 involvement in glial differentiation of neuroprogenitor cells through APP signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Deregulation of sphingolipid metabolism in Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Dietary fats, cholesterol and iron as risk factors for Parkinson's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Endosomal accumulation of GM1 ganglioside-bound amyloid beta-protein in neurons of aged monkey brains.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Prediction and longitudinal study of CSF biomarkers in mild cognitive impairment

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Oxysterols, cholesterol homeostasis, and Alzheimer disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Brain-derived neurotrophic factor regulates cholesterol metabolism for synapse development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Iron: the Redox-active center of oxidative stress in Alzheimer disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Calcium, iron and neuronal function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Amyloid beta-protein and lipid metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Consequences of expressing mutants of the hemochromatosis gene (HFE) into a human neuronal cell line lacking endogenous HFE.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Rafts are required for acetylcholine receptor clustering

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Cholesterol reduction by methyl-beta-cyclodextrin attenuates the delta opioid receptor-mediated signaling in neuronal cells but enhances it in non-neuronal cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

HFE mutations and Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Molecular anatomy of a trafficking organelle

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

White matter rafting--membrane microdomains in myelin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Myelin associated glycoprotein cross-linking triggers its partitioning into lipid rafts, specific signaling events and cytoskeletal rearrangements in oligodendrocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Cholesterol and lipid microdomains stabilize the postsynapse at the neuromuscular junction.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Modulation of beta-amyloid precursor protein trafficking and processing by the low density lipoprotein receptor family

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Rafts in oligodendrocytes: evidence and structure-function relationship

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Oxidative stress and iron imbalance in Alzheimer disease: how rust became the fuss!

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Lipid imbalance in the neurological disorder, Niemann-Pick C disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Monocyte chemoattractant protein-1 induces a novel transcription factor that causes cardiac myocyte apoptosis and ventricular dysfunction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Metal exposure and Alzheimer's pathogenesis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Regulation of autophagy by sphingosine kinase 1 and its role in cell survival during nutrient starvation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Cholesterol and Alzheimer's disease--is there a relation?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Cholesterol in Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Nanoparticle and other metal chelation therapeutics in Alzheimer disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Seeing spots: complex phase behavior in simple membranes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

A TrkA-to-p75NTR molecular switch activates amyloid beta-peptide generation during aging

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

LRP and Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Structure and physiologic function of the low-density lipoprotein receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

GM1 ganglioside and the seeding of amyloid in Alzheimer's disease: endogenous seed for Alzheimer amyloid

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Metals and amyloid-beta in Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Spatial segregation of gamma-secretase and substrates in distinct membrane domains

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Phosphorylation-specific prolyl isomerization: is there an underlying theme?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Hemochromatosis and iron-overload screening in a racially diverse population.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Iron-sulphur cluster biogenesis and mitochondrial iron homeostasis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Biogenesis of cytosolic ribosomes requires the essential iron-sulphur protein Rli1p and mitochondria

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

BDNF-induced recruitment of TrkB receptor into neuronal lipid rafts: roles in synaptic modulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Astroglial expression of ceramide in Alzheimer's disease brains: a role during neuronal apoptosis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Neuronal membrane cholesterol loss enhances amyloid peptide generation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Alzheimer disease: mercury as pathogenetic factor and apolipoprotein E as a moderator.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Increased incidence of the Hfe mutation in amyotrophic lateral sclerosis and related cellular consequences

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Cholesterol, statins and dementia.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Infantile-onset symptomatic epilepsy syndrome caused by a homozygous loss-of-function mutation of GM3 synthase.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Got RIP? Presenilin-dependent intramembrane proteolysis in growth factor receptor signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

A nontransgenic mouse model shows inducible amyloid-beta (Abeta) peptide deposition and elucidates the role of apolipoprotein E in the amyloid cascade

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Metal and inflammatory targets for Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Cholesterol at the crossroads: Alzheimer's disease and lipid metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Prevalent overexpression of prolyl isomerase Pin1 in human cancers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Oxidative stress and redox-active iron in Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Redox metals in Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Iron, atherosclerosis, and neurodegeneration: a key role for cholesterol in promoting iron-dependent oxidative damage?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

GM1 ganglioside regulates the proteolysis of amyloid precursor protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Brain cholesterol: long secret life behind a barrier.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Raft disorganization leads to reduced plasmin activity in Alzheimer's disease brains

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Formation of 7-dehydrocholesterol-containing membrane rafts in vitro and in vivo, with relevance to the Smith-Lemli-Opitz syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Smith-Lemli-Opitz syndrome and the DHCR7 gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

HFE, the MHC and hemochromatosis: Paradigm for an extended function for MHC class I

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

The metallobiology of Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Role of cholesterol in synapse formation and function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Cyp46 (24S-cholesterol hydroxylase): a genetic risk factor for Alzheimer disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Outsourcing in the brain: do neurons depend on cholesterol delivery by astrocytes?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

The hemochromatosis protein HFE inhibits iron export from macrophages.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Galactolipids are molecular determinants of myelin development and axo-glial organization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Genetic haemochromatosis: genes and mutations associated with iron loading

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Regulation of oligodendrocyte development in the vertebrate CNS.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Ganglioside function in calcium homeostasis and signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

ABCA1 and scavenger receptor class B, type I, are modulators of reverse sterol transport at an in vitro blood-brain barrier constituted of porcine brain capillary endothelial cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Lipid rafts in neuronal signaling and function.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Apolipoprotein E: a major piece in the Alzheimer's disease puzzle.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Impact of endogenous nitric oxide on microglial cell energy metabolism and labile iron pool

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Apolipoprotein E (ApoE) isoform-dependent lipid release from astrocytes prepared from human ApoE3 and ApoE4 knock-in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

The Ceramide-centric universe of lipid-mediated cell regulation: stress encounters of the lipid kind

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Sphingosine 1-phosphate, a key cell signaling molecule

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Regulation of transferrin-mediated iron uptake by HFE, the protein defective in hereditary hemochromatosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Cholesterol and other membrane active sterols: from membrane evolution to "rafts".

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Iron and iron management proteins in neurobiology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Interactions of cholesterol with lipid bilayers: the preferred configuration and fluctuations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Characterization of high-affinity binding between gangliosides and amyloid beta-protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

SNAREs are concentrated in cholesterol-dependent clusters that define docking and fusion sites for exocytosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Cholesterol metabolism in the brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Redox-active iron mediates amyloid-beta toxicity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

The cell biology and physiologic relevance of ApoE recycling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Geography of HFE C282Y and H63D mutations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

The role of metals in neurodegenerative diseases.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Transferrin receptor 2: continued expression in mouse liver in the face of iron overload and in hereditary hemochromatosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

In vivo evaluation of brain iron in Alzheimer disease using magnetic resonance imaging

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Amyloid precursor protein in unique cholesterol-rich microdomains different from caveolae-like domains

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

The hemochromatosis protein HFE competes with transferrin for binding to the transferrin receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

The magnitude of brain lipid peroxidation correlates with the extent of degeneration but not with density of neuritic plaques or neurofibrillary tangles or with APOE genotype in Alzheimer's disease patients

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Amyloid and lipids in the pathology of Alzheimer disease.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Association of HFE protein with transferrin receptor in crypt enterocytes of human duodenum

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Cholesterol homeostasis in human brain: turnover of 24S-hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Oxygen activating nonheme iron enzymes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Nascent astrocyte particles differ from lipoproteins in CSF.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Regulation of ceramide production and apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Abnormal localization of iron regulatory protein in Alzheimer's disease.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Serum total cholesterol, apolipoprotein E epsilon 4 allele, and Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Importance of a novel oxidative mechanism for elimination of brain cholesterol. Turnover of cholesterol and 24(S)-hydroxycholesterol in rat brain as measured with 18O2 techniques in vivo and in vitro.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Hereditary hemochromatosis: effects of C282Y and H63D mutations on association with beta2-microglobulin, intracellular processing, and cell surface expression of the HFE protein in COS-7 cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Aconitase and mitochondrial iron-sulphur protein deficiency in Friedreich ataxia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Acceleration of amyloid fibril formation by specific binding of Abeta-(1-40) peptide to ganglioside-containing membrane vesicles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

A new function for the LDL receptor: transcytosis of LDL across the blood-brain barrier

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Membrane modifications of red blood cells in Alzheimer's disease.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Oxidative stress hypothesis in Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

The hemochromatosis founder mutation in HLA-H disrupts beta2-microglobulin interaction and cell surface expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Axonal amyloid precursor protein expressed by neurons in vitro is present in a membrane fraction with caveolae-like properties.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Increasing age alters transbilayer fluidity and cholesterol asymmetry in synaptic plasma membranes of mice.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

A human peptidyl-prolyl isomerase essential for regulation of mitosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Role of ceramide in cellular senescence

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Free radicals as mediators of tissue injury and disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

In vivo MR evaluation of age-related increases in brain iron.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Upregulation of the low density lipoprotein receptor at the blood-brain barrier: intercommunications between brain capillary endothelial cells and astrocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

The effect of iron overload on rat plasma and liver oxidant status in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Iron levels modulate alpha-secretase cleavage of amyloid precursor protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Hereditary haemochromatosis: a case of iron accumulation in the basal ganglia associated with a parkinsonian syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

A quantitative analysis of isoferritins in select regions of aged, parkinsonian, and Alzheimer's diseased brains

5 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

5 July 2018

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

The isolation and biochemical characterization of three subfractions of myelin from central nervous tissue of the adult rat

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Lipid peroxidation and associated hepatic organelle dysfunction in iron overload

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Deep gray matter hypointensity patterns with aging in healthy adults: MR imaging at 1.5 T.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

A histochemical study of iron, transferrin, and ferritin in Alzheimer's diseased brains.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Regional distribution of iron and iron-regulatory proteins in the brain in aging and Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Lipid composition in different regions of the brain in Alzheimer's disease/senile dementia of Alzheimer's type

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Association of HLA-A3 and HLA-B14 antigens with idiopathic haemochromatosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Dyslipidemia in ALS: good, bad, or unclear?

5 July 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

H63D mutation in hemochromatosis alters cholesterol metabolism and induces memory impairment.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Plasma HDL levels highly correlate with cognitive function in exceptional longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

MRI evaluation of brain iron in earlier- and later-onset Parkinson's disease and normal subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Brain ferritin iron may influence age- and gender-related risks of neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Developmental changes in the association of NMDA receptors with lipid rafts.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

APOE polymorphism and clinical duration determine regional neuropathology in Swedish APP(670, 671) mutation carriers: implications for late-onset Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Plasma levels of 24S-hydroxycholesterol in patients with neurological diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Apoptotic stress pathway activation mediated by iron on endothelial cells in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Lower serum lipid levels are related to respiratory impairment in patients with ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

CNS integrins switch growth factor signalling to promote target-dependent survival

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

CAT53 and HFE alleles in Alzheimer's disease: a putative protective role of the C282Y HFE mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Correlation of iron in the hippocampus with MMSE in patients with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Hereditary hemochromatosis genotypes and risk of ischemic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Deposition of iron and beta-amyloid plaques is associated with cortical cellular damage in rabbits fed with long-term cholesterol-enriched diets.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Evidence for a membrane lipid defect in Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Regional specificity of membrane instability in Alzheimer's disease brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Changes of oxidative stress in various tissues by long-term administration of vitamin E in hypercholesterolemic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

The effect of age on the non-haemin iron in the human brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: potential role in disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

A seed for Alzheimer amyloid in the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Age-associated increases in heme oxygenase-1 and ferritin immunoreactivity in the autopsied brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Murine synaptosomal lipid raft protein and lipid composition are altered by expression of human apoE 3 and 4 and by increasing age.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Pro-apoptotic signaling in neuronal cells following iron and amyloid beta peptide neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

A detergent-insoluble membrane compartment contains A beta in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Changes in human plasma levels of the brain specific oxysterol 24S-hydroxycholesterol during progression of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Are the CSF levels of 24S-hydroxycholesterol a sensitive biomarker for mild cognitive impairment?

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

C282Y polymorphism in the HFE gene is associated with risk of breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Transferrin C2 allele, haemochromatosis gene mutations, and risk for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Microglial dystrophy in the aged and Alzheimer's disease brain is associated with ferritin immunoreactivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Aluminum, iron, and zinc ions promote aggregation of physiological concentrations of beta-amyloid peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Increasing striatal iron content associated with normal aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

The synaptophysin/synaptobrevin interaction critically depends on the cholesterol content.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Structural membrane alterations in Alzheimer brains found to be associated with regional disease development; increased density of gangliosides GM1 and GM2 and loss of cholesterol in detergent-resistant membrane domains

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

The Presence of Amyloid β-Protein in the Detergent-Insoluble Membrane Compartment of Human Neuroblastoma Cells†

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Cholesterol masks membrane glycosphingolipid tumor-associated antigens to reduce their immunodetection in human cancer biopsies

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Changes in phospholipid composition of erythrocyte membrane in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Increased iron staining in the cerebral cortex of cholesterol fed rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

24S-hydroxycholesterol in cerebrospinal fluid is elevated in early stages of dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

A central role for ceramide in the age-related acceleration of apoptosis in the female germline

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Brain membrane phospholipid alterations in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Increase of brain oxidative stress in mild cognitive impairment: a possible predictor of Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Association of HFE mutations with neurodegeneration and oxidative stress in Alzheimer's disease and correlation with APOE

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Implication of apoE isoforms in cholesterol metabolism by primary rat hippocampal neurons and astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

An iron-responsive element type II in the 5'-untranslated region of the Alzheimer's amyloid precursor protein transcript

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

High cholesterol level is essential for myelin membrane growth

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

The hemochromatosis gene affects the age of onset of sporadic Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Cholesterol, GM1, and autism.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

The role of iron in beta amyloid toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Association between hemochromatosis (HFE) gene mutation carrier status and the risk of colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Astrocytes and microglia respond to estrogen with increased apoE mRNA in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Dysfunction of the cholesterol biosynthetic pathway in Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Cyp46 (24S-Cholesterol Hydroxylase)

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Induction of calcium influx through TRPC5 channels by cross-linking of GM1 ganglioside associated with alpha5beta1 integrin initiates neurite outgrowth.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

GM1-ganglioside-induced Abeta assembly on synaptic membranes of cultured neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Hippocampal volume change in the Alzheimer Disease Cholesterol-Lowering Treatment trial

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Involvement of ApoE E4 and H63D in sporadic Alzheimer's disease in a folate-supplemented Ontario population.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

The prolyl isomerase Pin1 is a novel prognostic marker in human prostate cancer.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Specificity and potential mechanism of sulfatide deficiency in Alzheimer's disease: an electrospray ionization mass spectrometric study

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Low cholesterol, cognitive function and Alzheimer s disease in a community population with cognitive impairment.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Iron metabolism and Parkinson's disease.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Membrane components separate early-onset Alzheimer's disease from senile dementia of the Alzheimer type.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Membrane lipids, selectively diminished in Alzheimer brains, suggest synapse loss as a primary event in early-onset form (type I) and demyelination in late-onset form (type II).

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Studies on the synthesis of cholesterol in the brain of the human fetus.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Cholesterol modulates glycolipid conformation and receptor activity

29 October 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00165

Evidence that the major oxysterols in human circulation originate from distinct pools of cholesterol: a stable isotope study

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Plasma levels of 24S-hydroxycholesterol reflect the balance between cerebral production and hepatic metabolism and are inversely related to body surface

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086322

Effect of iron overload and iron deficiency on atherosclerosis in the hypercholesterolemic rabbit

10 December 2018

1 reference

12 December 2020

Complete scanning of the hereditary hemochromatosis gene (HFE) by use of denaturing HPLC

1 reference

12 December 2020

The Cys282Tyr polymorphism in the HFE gene in Australian Parkinson's disease patients

1 reference

12 December 2020

Iron overload in hypercholesterolemic rats affects iron homeostasis and serum lipids but not blood pressure

1 reference

12 December 2020

Transferrin and iron in normal, Alzheimer's disease, and Parkinson's disease brain regions

1 reference

12 December 2020

Formation of toxic fibrils of Alzheimer's amyloid beta-protein-(1-40) by monosialoganglioside GM1, a neuronal membrane component

1 reference

12 December 2020

The basal ganglia in haemochromatosis

1 reference

12 December 2020

Plasma 24S-hydroxycholesterol (cerebrosterol) is increased in Alzheimer and vascular demented patients

1 reference

12 December 2020

Dietary iron overload and induced lipid peroxidation are associated with impaired plasma lipid transport and hepatic sterol metabolism in rats

1 reference

12 December 2020

Apolipoprotein E exhibits isoform-specific promotion of lipid efflux from astrocytes and neurons in culture

1 reference

12 December 2020

Lipid peroxidation and glutathione system in hyperlipemic rabbits: influence of olive oil administration

1 reference

12 December 2020

Association of the H63D polymorphism in the hemochromatosis gene with sporadic ALS

1 reference

12 December 2020

The major histocompatibility complex-encoded class I-like HFE abrogates endocytosis of transferrin receptor by inducing receptor phosphorylation

1 reference

12 December 2020

Are hereditary hemochromatosis mutations involved in Alzheimer disease?

1 reference

12 December 2020

Interactions of apolipoprotein E genotype, total cholesterol level, age, and sex in prediction of Alzheimer's disease: a case-control study

1 reference

12 December 2020

Metabolism of cholesterol and triacylglycerol in cultured chick neuronal cells, glial cells, and fibroblasts: accumulation of esterified cholesterol in serum-free culture

1 reference

12 December 2020

Estrogen Up-regulates Apolipoprotein E (ApoE) Gene Expression by Increasing ApoE mRNA in the Translating Pool via the Estrogen Receptor α-Mediated Pathway

1 reference

12 December 2020

The origin of the hydroxyl radical oxygen in the Fenton reaction

1 reference

12 December 2020

Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins

1 reference

12 December 2020

Hemochromatosis gene mutations among Finnish male breast and prostate cancer patients

1 reference

12 December 2020

Interaction of the H63D mutation in the hemochromatosis gene with the apolipoprotein E epsilon 4 allele modulates age at onset of Alzheimer's disease

1 reference

12 December 2020

Iron-salicylate complex induces peroxidation, alters hepatic lipid profile and affects plasma lipoprotein composition

1 reference

12 December 2020

Cholesterol for synthesis of myelin is made locally, not imported into brain

1 reference

12 December 2020

Identifiers

DOI

10.3389/FPHAR.2014.00165

1 reference

29 July 2017

1 reference

29 July 2017

1 reference

PubMed ID

25071582