New insights into redox homeostasis as a therapeutic target in B-cell malignancies. (Q33797951)

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17 March 2020

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14 September 2020

New insights into redox homeostasis as a therapeutic target in B-cell malignancies (English)

1 reference

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17 March 2020

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3 April 2019

20 August 2019

14 September 2020

physiological phenomenon

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20 August 2019

1 reference

14 September 2020

Agnieszka Graczyk-Jarzynka

1

1 reference

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17 March 2020

Radosław Zagożdżon

2

1 reference

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17 March 2020

Angelika Muchowicz

3

1 reference

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17 March 2020

Przemysław Juszczyński

5

1 reference

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17 March 2020

Małgorzata Firczuk

6

1 reference

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17 March 2020

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Marta Siernicka

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17 March 2020

publication date

1 July 2017

4 references

3 April 2019

20 August 2019

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17 March 2020

14 September 2020

Current Opinion in Hematology

4 references

3 April 2019

20 August 2019

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14 September 2020

24

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17 March 2020

page(s)

393-401

1 reference

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17 March 2020

issue

4

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Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

17 March 2020

copyright license

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3 April 2019

20 August 2019

on focus list of Wikimedia project

14 September 2020

ScienceSource

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Discovery of a drug targeting microenvironmental support for lymphoma cells by screening using patient-derived xenograft cells

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Regulation of catalase expression in healthy and cancerous cells

28 July 2018

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Dual targeting of the thioredoxin and glutathione antioxidant systems in malignant B cells: a novel synergistic therapeutic approach

28 July 2018

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Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support.

28 July 2018

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Targeting antioxidants for cancer therapy

28 July 2018

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Phase 2 study of imexon, a prooxidant molecule, in relapsed and refractory B-cell non-Hodgkin lymphoma

28 July 2018

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The tumour microenvironment in B cell lymphomas

28 July 2018

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Genetic polymorphisms in oxidative stress-related genes are associated with outcomes following treatment for aggressive B-cell non-Hodgkin lymphoma

28 July 2018

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Adenanthin targets proteins involved in the regulation of disulphide bonds.

28 July 2018

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Auranofin induces lethal oxidative and endoplasmic reticulum stress and exerts potent preclinical activity against chronic lymphocytic leukemia

28 July 2018

1 reference

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Piperlongumine inhibits proliferation and survival of Burkitt lymphoma in vitro

28 July 2018

1 reference

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Ethacrynic acid and a derivative enhance apoptosis in arsenic trioxide-treated myeloid leukemia and lymphoma cells: the role of glutathione S-transferase p1-1.

28 July 2018

1 reference

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Metabolic signatures uncover distinct targets in molecular subsets of diffuse large B cell lymphoma

28 July 2018

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Ascorbic acid kills Epstein-Barr virus positive Burkitt lymphoma cells and Epstein-Barr virus transformed B-cells in vitro, but not in vivo

28 July 2018

1 reference

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Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukaemia

28 July 2018

1 reference

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Studies toward novel peptidomimetic inhibitors of thioredoxin-thioredoxin reductase system

28 July 2018

1 reference

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Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)

28 July 2018

1 reference

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Superoxide dismutases: role in redox signaling, vascular function, and diseases

28 July 2018

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Loss of thioredoxin reductase 1 renders tumors highly susceptible to pharmacologic glutathione deprivation

28 July 2018

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Bcr-Abl-mediated redox regulation of the PI3K/AKT pathway

28 July 2018

1 reference

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A novel function of peroxiredoxin 1 (Prx-1) in apoptosis signal-regulating kinase 1 (ASK1)-mediated signaling pathway

28 July 2018

1 reference

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A novel group of glutaredoxins in the cis-Golgi critical for oxidative stress resistance

28 July 2018

1 reference

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The cystine/cysteine cycle: a redox cycle regulating susceptibility versus resistance to cell death

28 July 2018

1 reference

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Genetic polymorphisms in the oxidative stress pathway and susceptibility to non-Hodgkin lymphoma

28 July 2018

1 reference

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Inhibition of glutathione synthesis overcomes Bcl-2-mediated topoisomerase inhibitor resistance and induces nonapoptotic cell death via mitochondrial-independent pathway

28 July 2018

1 reference

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Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues

28 July 2018

1 reference

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A redox signature score identifies diffuse large B-cell lymphoma patients with a poor prognosis

28 July 2018

1 reference

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Chemical basis for the biological activity of imexon and related cyanoaziridines

28 July 2018

1 reference

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ATP-dependent reduction of cysteine–sulphinic acid by S. cerevisiae sulphiredoxin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5470855

Hydrogen peroxide as second messenger in lymphocyte activation

28 July 2018

1 reference

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Physiological functions of thioredoxin and thioredoxin reductase

28 July 2018

1 reference

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As2O3 induces apoptosis of the human B lymphoma cell line MBC-1.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5470855

Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5470855

Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5470855

FOXO1 is a TXN- and p300-dependent sensor and effector of oxidative stress in diffuse large B-cell lymphomas characterized by increased oxidative metabolism

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5470855

Sensitization of acute lymphoblastic leukemia cells for LCL161-induced cell death by targeting redox homeostasis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5470855

A hostel for the hostile: the bone marrow niche in hematologic neoplasms

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5470855

Preclinical activity of the repurposed drug auranofin in classical Hodgkin lymphoma.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5470855

Arsenic trioxide synergistically potentiates the cytotoxic effect of fludarabine in chronic lymphocytic leukemia cells by further inactivating the Akt and ERK signaling pathways.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5470855

SK053 triggers tumor cells apoptosis by oxidative stress-mediated endoplasmic reticulum stress

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5470855

Impairment of antioxidant defense via glutathione depletion sensitizes acute lymphoblastic leukemia cells for Smac mimetic-induced cell death

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5470855

Mitochondrial metabolism contributes to oxidative stress and reveals therapeutic targets in chronic lymphocytic leukemia

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5470855

ETV6/RUNX1 induces reactive oxygen species and drives the accumulation of DNA damage in B cells.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5470855

Modulation of oxidative stress as an anticancer strategy

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5470855

Thioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signaling

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5470855

30 October 2018

Glutathione peroxidases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5470855

Over-expression of Thioredoxin-1 mediates growth, survival, and chemoresistance and is a druggable target in diffuse large B-cell lymphoma

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5470855

Buthionine sulfoximine enhancement of arsenic trioxide-induced apoptosis in leukemia and lymphoma cells is mediated via activation of c-Jun NH2-terminal kinase and up-regulation of death receptors.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5470855

Polymorphisms in oxidative stress genes and risk for non-Hodgkin lymphoma

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5470855

Arsenic trioxide-induced apoptosis of human malignant lymphoma cell lines and its mechanisms

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5470855

Structure, mechanism and regulation of peroxiredoxins

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5470855

Sulfasalazine, a potent suppressor of lymphoma growth by inhibition of the x(c)- cystine transporter: a new action for an old drug

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5470855

Correlation of urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG), a biomarker of oxidative DNA damage, and clinical features of hematological disorders: a pilot study.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5470855

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5470855

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5470855

Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5470855

c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28402987

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1097/MOH.0000000000000351

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28402987%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28402987%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

1 reference