The specificity of trimming of MHC class I-presented peptides in the endoplasmic reticulum. (Q33791476)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828632%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

The specificity of trimming of MHC class I-presented peptides in the endoplasmic reticulum (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828632%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

main subject

endoplasmic reticulum

0 references

author

Ian A. York

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828632%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

author name string

Arron Hearn

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828632%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Kenneth L Rock

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828632%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

language of work or name

English

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publication date

14 October 2009

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828632%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

published in

Journal of Immunology

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9 February 2020

volume

183

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9 February 2020

issue

9

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9 February 2020

page(s)

5526-5536

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The internal sequence of the peptide-substrate determines its N-terminus trimming by ERAP1.

9 February 2020

cites work

1 reference

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Immunodominant, protective response to the parasite Toxoplasma gondii requires antigen processing in the endoplasmic reticulum.

4 July 2018

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Characterizing the N-terminal processing motif of MHC class I ligands

4 July 2018

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ERAAP synergizes with MHC class I molecules to make the final cut in the antigenic peptide precursors in the endoplasmic reticulum

4 July 2018

1 reference

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Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance.

4 July 2018

1 reference

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In vivo role of ER-associated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules

4 July 2018

1 reference

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The ER aminopeptidase, ERAP1, trims precursors to lengths of MHC class I peptides by a "molecular ruler" mechanism.

4 July 2018

1 reference

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All the peptides that fit: the beginning, the middle, and the end of the MHC class I antigen-processing pathway

4 July 2018

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The oxytocinase subfamily of M1 aminopeptidases

4 July 2018

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Pcleavage: an SVM based method for prediction of constitutive proteasome and immunoproteasome cleavage sites in antigenic sequences

4 July 2018

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A mutant cell with a novel defect in MHC class I quality control

4 July 2018

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Cell biology of antigen processing in vitro and in vivo

4 July 2018

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Post-proteasomal antigen processing for major histocompatibility complex class I presentation

4 July 2018

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Identifying MHC class I epitopes by predicting the TAP transport efficiency of epitope precursors.

4 July 2018

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Human leukocyte-derived arginine aminopeptidase. The third member of the oxytocinase subfamily of aminopeptidases

4 July 2018

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Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I.

4 July 2018

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The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues

4 July 2018

1 reference

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An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides

4 July 2018

1 reference

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ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum

4 July 2018

1 reference

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The importance of the proteasome and subsequent proteolytic steps in the generation of antigenic peptides.

4 July 2018

1 reference

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Protein degradation and the generation of MHC class I-presented peptides.

4 July 2018

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The murine cytomegalovirus pp89 immunodominant H-2Ld epitope is generated and translocated into the endoplasmic reticulum as an 11-mer precursor peptide

4 July 2018

1 reference

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26S proteasomes and immunoproteasomes produce mainly N-extended versions of an antigenic peptide

4 July 2018

1 reference

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Human transporters associated with antigen processing (TAPs) select epitope precursor peptides for processing in the endoplasmic reticulum and presentation to T cells

4 July 2018

1 reference

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Degradation of cell proteins and the generation of MHC class I-presented peptides

4 July 2018

1 reference

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Immunodominance in major histocompatibility complex class I-restricted T lymphocyte responses

4 July 2018

1 reference

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Interferon-gamma can stimulate post-proteasomal trimming of the N terminus of an antigenic peptide by inducing leucine aminopeptidase

4 July 2018

1 reference

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Protective immunity does not correlate with the hierarchy of virus-specific cytotoxic T cell responses to naturally processed peptides

4 July 2018

1 reference

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Two distinct proteolytic processes in the generation of a major histocompatibility complex class I-presented peptide

4 July 2018

1 reference

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Peptide size selection by the major histocompatibility complex-encoded peptide transporter

4 July 2018

1 reference

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Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

4 July 2018

1 reference

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Major differences in transporter associated with antigen presentation (TAP)-dependent translocation of MHC class I-presentable peptides and the effect of flanking sequences

4 July 2018

1 reference

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Chemistry of peptides associated with MHC class I and class II molecules

4 July 2018

1 reference

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Herpes simplex virus turns off the TAP to evade host immunity

4 July 2018

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Antigen processing in vivo and the elicitation of primary CTL responses

4 July 2018

1 reference

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Proline motifs in peptides and their biological processing

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855122

The peptide-binding motif for the human transporter associated with antigen processing

4 July 2018

1 reference

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The 19-kDa glycoprotein coded by region E3 of adenovirus. Purification, characterization, and structural analysis.

4 July 2018

1 reference

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In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855122

The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855122

Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855122

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30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855122

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30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855122

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30 October 2018

1 reference

12 December 2020

Transporter Associated with Antigen Processing Preselection of Peptides Binding to the MHC: A Bioinformatic Evaluation

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12 December 2020

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12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.0803663

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828632%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828632%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference