STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes (Q33784496)

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English	STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes	scientific article

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scholarly article

1 reference

Europe PubMed Central

29 July 2017

STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes (English)

1 reference

Europe PubMed Central

29 July 2017

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Mariusz A Wasik

6

object named as

Mariusz A Wasik

1 reference

Europe PubMed Central

29 July 2017

3

object named as

Michal Marzec

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Europe PubMed Central

29 July 2017

author name string

Qian Zhang

1

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Europe PubMed Central

29 July 2017

Hong Y Wang

2

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Europe PubMed Central

29 July 2017

Puthiyaveettil N Raghunath

4

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Europe PubMed Central

29 July 2017

Tomohiko Nagasawa

5

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Europe PubMed Central

29 July 2017

language of work or name

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publication date

3 May 2005

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Europe PubMed Central

29 July 2017

Proceedings of the National Academy of Sciences of the United States of America

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Europe PubMed Central

29 July 2017

102

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Europe PubMed Central

29 July 2017

6948-6953

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Europe PubMed Central

29 July 2017

19

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Europe PubMed Central

29 July 2017

Novel peptidomimetic inhibitors of signal transducer and activator of transcription 3 dimerization and biological activity.

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SOCS1 and SHP1 hypermethylation in multiple myeloma: implications for epigenetic activation of the Jak/STAT pathway

1 reference

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Role of the DNA methyltransferase variant DNMT3b3 in DNA methylation.

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Gene silencing in cancer in association with promoter hypermethylation

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Epigenetic targets in hematopoietic malignancies

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Vav1 dephosphorylation by the tyrosine phosphatase SHP-1 as a mechanism for inhibition of cellular cytotoxicity

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A phase I pharmacokinetic and pharmacodynamic study of the DNA methyltransferase 1 inhibitor MG98 administered twice weekly

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DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells

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DNA methylation and chromatin - unraveling the tangled web.

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A road map for those who don't know JAK-STAT

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Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death

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Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

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Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma

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DNA binding specificity of different STAT proteins. Comparison of in vitro specificity with natural target sites

1 reference

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Lack of phosphotyrosine phosphatase SHP-1 expression in malignant T-cell lymphoma cells results from methylation of the SHP-1 promoter

1 reference

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DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

1 reference

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CREB-binding protein and p300: molecular integrators of hematopoietic transcription.

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DNA binding site selection of dimeric and tetrameric Stat5 proteins reveals a large repertoire of divergent tetrameric Stat5a binding sites

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Stat protein transactivation domains recruit p300/CBP through widely divergent sequences

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Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines

1 reference

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Activation of Jak/STAT proteins involved in signal transduction pathway mediated by receptor for interleukin 2 in malignant T lymphocytes derived from cutaneous anaplastic large T-cell lymphoma and Sezary syndrome

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Effective dephosphorylation of Src substrates by SHP-1.

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Cooperation between STAT3 and c-jun suppresses Fas transcription.

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Thyrotropin-mediated repression of class II trans-activator expression in thyroid cells: involvement of STAT3 and suppressor of cytokine signaling.

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Signal transduction pathways regulated by prolactin and Src result in different conformations of activated Stat5b

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Gene silencing of the tyrosine phosphatase SHP1 gene by aberrant methylation in leukemias/lymphomas.

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The fundamental role of epigenetic events in cancer

1 reference

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12 December 2020

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Identifiers

10.1073/PNAS.0501959102

1 reference

Europe PubMed Central

29 July 2017

2005PNAS..102.6948Z

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1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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