DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells (Q34166536)

31 July 2017

DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells (English)

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31 July 2017

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Marie-France Robert

1

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31 July 2017

Steves Morin

2

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31 July 2017

Normand Beaulieu

3

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31 July 2017

France Gauthier

4

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31 July 2017

Ian C Chute

5

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31 July 2017

Annie Barsalou

6

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31 July 2017

A Robert MacLeod

7

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31 July 2017

language of work or name

English

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publication date

23 December 2002

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31 July 2017

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31 July 2017

33

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31 July 2017

61-65

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31 July 2017

1

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https://scigraph.springernature.com/pub.10.1038/ng1068

31 July 2017

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Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

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Suppression of intestinal neoplasia by DNA hypomethylation.

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Down-regulation of human DNA-(cytosine-5) methyltransferase induces cell cycle regulators p16(ink4A) and p21(WAF/Cip1) by distinct mechanisms

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CpG methylation is maintained in human cancer cells lacking DNMT1.

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7 January 2021

DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

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7 January 2021

An essential role for DNA methyltransferase DNMT3B in cancer cell survival

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DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

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Role for DNA methylation in genomic imprinting

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DNA (cytosine-5)-methyltransferases in mouse cells and tissues. Studies with a mechanism-based probe.

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5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.

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7 January 2021

Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

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7 January 2021

A sensitive new method for rapid detection of abnormal methylation patterns in global DNA and within CpG islands

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7 January 2021

Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation

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7 January 2021

5-Azadeoxycytidine induced undercondensation in the giant X chromosomes of Microtus agrestis

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7 January 2021

The effects of 5-azacytidine and 5-azadeoxycytidine on chromosome structure and function: implications for methylation-associated cellular processes

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7 January 2021

Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements

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7 January 2021

Conditional mouse models of sporadic cancer

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7 January 2021

Dnmt3a and Dnmt3b are transcriptional repressors that exhibit unique localization properties to heterochromatin

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7 January 2021

Mammalian DNA methyltransferases show different subnuclear distributions

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7 January 2021

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

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7 January 2021

Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumours.

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7 January 2021

Identifiers

DOI

10.1038/NG1068

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Dimensions Publication ID

31 July 2017

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