Epigenetic targets in hematopoietic malignancies (Q35551110)

8 August 2017

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title

Epigenetic targets in hematopoietic malignancies (English)

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8 August 2017

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https://api.crossref.org/works/10.1038/SJ.ONC.1206814

18 March 2024

author name string

Rainer Claus

series ordinal

1

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8 August 2017

Michael Lübbert

series ordinal

2

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8 August 2017

language of work or name

English

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publication date

1 September 2003

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8 August 2017

29 September 2003

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14528273

full work available at URL

18 March 2024

https://www.nature.com/articles/1206814.pdf

file format

Portable Document Format

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https://api.crossref.org/works/10.1038/SJ.ONC.1206814

https://www.nature.com/articles/1206814

18 March 2024

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https://api.crossref.org/works/10.1038/SJ.ONC.1206814

18 March 2024

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8 August 2017

22

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8 August 2017

6489-6496

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8 August 2017

42

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1206814

8 August 2017

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cites work

CpG islands and genes

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CpG islands in vertebrate genomes

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

Mapping patterns of CpG island methylation in normal and neoplastic cells implicates both upstream and downstream regions in de novo methylation.

21 January 2018

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Lentivirus administration to rat muscle provides efficient sustained expression of erythropoietin.

21 January 2018

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De novo methylation of the MyoD1 CpG island during the establishment of immortal cell lines

21 January 2018

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Relationships between chromatin organization and DNA methylation in determining gene expression

21 January 2018

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Human natural killer cells with polyclonal lectin and immunoglobulinlike receptors develop from single hematopoietic stem cells with preferential expression of NKG2A and KIR2DL2/L3/S2.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

Susceptibility of nonpromoter CpG islands to de novo methylation in normal and neoplastic cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

The antileukaemic activity of 5-Aza-2 deoxycytidine (Aza-dC) in patients with relapsed and resistant leukaemia.

21 January 2018

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DNA methylation in health and disease

21 January 2018

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Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: a study of the cancer and leukemia group B.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

Low-dose 5-aza-2'-deoxycytidine, a DNA hypomethylating agent, for the treatment of high-risk myelodysplastic syndrome: a multicenter phase II study in elderly patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

Methylation status of the p15INK4B gene in hematopoietic progenitors and peripheral blood cells in myelodysplastic syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Aberrant p15 gene promoter methylation in therapy-related myelodysplastic syndrome and acute myeloid leukaemia: clinicopathological and karyotypic associations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Gametic imprinting in mammals

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

CpG-rich islands and the function of DNA methylation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Methylation-induced repression--belts, braces, and chromatin

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Methylation of p15 and p16 genes in acute promyelocytic leukemia: potential diagnostic and prognostic significance

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Hypermethylation of gene promoters in hematological neoplasia

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Review of alterations of the cyclin-dependent kinase inhibitor INK4 family genes p15, p16, p18 and p19 in human leukemia-lymphoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Breaking the silence: the rise of epigenetic therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Different incidence and pattern of p15INK4b and p16INK4a promoter region hypermethylation in Hodgkin's and CD30-Positive non-Hodgkin's lymphomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Aberrant promoter methylation and silencing of the RASSF1A gene in pediatric tumors and cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

The absence of the p15INK4B gene alterations in adult patients with precursor B-cell acute lymphoblastic leukaemia is a favourable prognostic factor

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Aging, DNA methylation and cancer

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

β-adrenergic receptor induction in HeLa cells: Synergistic effect of 5-azacytidine and butyrate

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Cancer epigenetics comes of age

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Depsipeptide (FR 901228) promotes histone acetylation, gene transcription, apoptosis and its activity is enhanced by DNA methyltransferase inhibitors in AML1/ETO-positive leukemic cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Histone methylation in transcriptional control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Role of the histone deacetylase complex in acute promyelocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Cytogenetic responses in high-risk myelodysplastic syndrome following low-dose treatment with the DNA methylation inhibitor 5-aza-2'-deoxycytidine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Expression and subcellular localization of NRAMP1 in human neutrophil granules

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Inactivation of the cyclin-dependent kinase inhibitor p15INK4b by deletion and de novo methylation with independence of p16INK4a alterations in murine primary T-cell lymphomas.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Hypermethylation of p15/ink4b/MTS2 gene is differentially implicated among non-Hodgkin's lymphomas.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

DNA methylation levels in acute human leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

MODULATION OF HLA-DR ANTIGENS EXPRESSION IN HUMAN MYELOID LEUKAEMIA CELLS BY CYTARABINE AND 5-AZA-2'-DEOXYCYTIDINE

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

P15INK4B gene methylation and expression in normal, myelodysplastic, and acute myelogenous leukemia cells and in the marrow cells of cured lymphoma patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

5' CpG island hypermethylation is associated with transcriptional silencing of the p21(CIP1/WAF1/SDI1) gene and confers poor prognosis in acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Novel methylation targets in de novo acute myeloid leukemia with prevalence of chromosome 11 loci

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Changes in DNA methylation in neoplasia: pathophysiology and therapeutic implications.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

The expression of DNA methyltransferases and methyl-CpG-binding proteins is not associated with the methylation status of p14(ARF), p16(INK4a) and RASSF1A in human lung cancer cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Preclinical evaluation of antineoplastic activity of inhibitors of DNA methylation (5-aza-2'-deoxycytidine) and histone deacetylation (trichostatin A, depsipeptide) in combination against myeloid leukemic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Lack of p21(CIP1) DNA methylation in acute lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

5-Aza-2'-deoxycytidine (decitabine) treatment of hematopoietic malignancies: a multimechanism therapeutic approach?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Expression of cyclin-dependent kinase inhibitor p15(INK4B) during normal and leukemic myeloid differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Expression of p15(ink4b) gene during megakaryocytic differentiation of normal and myelodysplastic hematopoietic progenitors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Methylation of the p15(INK4B) gene in myelodysplastic syndrome: it can be detected early at diagnosis or during disease progression and is highly associated with leukaemic transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Methylation profiling in acute myeloid leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Continuous infusion of low-dose 5-Aza-2'-deoxycytidine in elderly patients with high-risk myelodysplastic syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206814

7 January 2021

Histone deacetylases: a common molecular target for differentiation treatment of acute myeloid leukemias?

series ordinal

29

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206814

18 March 2024

Identifiers

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Dimensions Publication ID

8 August 2017

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1 reference