CRISPR/Cas9-mediated p53 and Pten dual mutation accelerates hepatocarcinogenesis in adult hepatitis B virus transgenic mice (Q33765935)

29 July 2017

CRISPR/Cas9-mediated p53 and Pten dual mutation accelerates hepatocarcinogenesis in adult hepatitis B virus transgenic mice (English)

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29 July 2017

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11

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13 June 2020

author name string

Yongzhen Liu

1

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13 June 2020

Xuewei Qi

2

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13 June 2020

Zhenzhen Zeng

3

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13 June 2020

Lu Wang

4

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13 June 2020

Jie Wang

5

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13 June 2020

Ting Zhang

6

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13 June 2020

Qiang Xu

7

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13 June 2020

Congle Shen

8

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13 June 2020

Guangde Zhou

9

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13 June 2020

Shaomin Yang

10

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13 June 2020

Fengmin Lu

12

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13 June 2020

language of work or name

English

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publication date

5 June 2017

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29 July 2017

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13 June 2020

volume

7

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13 June 2020

issue

1

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13 June 2020

page(s)

2796

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Creative Commons Attribution 4.0 International

13 June 2020

copyright license

start time

5 June 2017

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April 2022 Public Data File from Crossref

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https://scigraph.springernature.com/pub.10.1038/s41598-017-03070-8

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Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses.

22 June 2018

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Integrative analysis of aberrant Wnt signaling in hepatitis B virus-related hepatocellular carcinoma

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1,8-Cineole Ameliorates Steatosis of Pten Liver Specific KO Mice via Akt Inactivation

22 June 2018

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Alpha fetoprotein mediates HBx induced carcinogenesis in the hepatocyte cytoplasm.

22 June 2018

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Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets

22 June 2018

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22 June 2018

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Reduced red blood cell count predicts poor survival after surgery in patients with primary liver cancer.

22 June 2018

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Simple and rapid in vivo generation of chromosomal rearrangements using CRISPR/Cas9 technology

22 June 2018

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Trans-ancestry mutational landscape of hepatocellular carcinoma genomes

22 June 2018

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22 June 2018

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Molecular mechanism of hepatitis B virus-induced hepatocarcinogenesis

22 June 2018

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The CRISPR/Cas9 System Facilitates Clearance of the Intrahepatic HBV Templates In Vivo

22 June 2018

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CRISPR-mediated direct mutation of cancer genes in the mouse liver

22 June 2018

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22 June 2018

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22 June 2018

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Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma

22 June 2018

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Identification of driver genes in hepatocellular carcinoma by exome sequencing

22 June 2018

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Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis

22 June 2018

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22 June 2018

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Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma

22 June 2018

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The functions and regulation of the PTEN tumour suppressor

22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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PTEN induces cell cycle arrest by decreasing the level and nuclear localization of cyclin D1.

22 June 2018

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

22 June 2018

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Structural and pathological effects of synthesis of hepatitis B virus large envelope polypeptide in transgenic mice

22 June 2018

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Hepatocarcinogenesis due to chronic liver cell injury in hepatitis B virus transgenic mice

22 June 2018

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Expression and prognostic role of tumor suppressor gene PTEN/MMAC1/TEP1 in hepatocellular carcinoma

22 June 2018

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21 January 2018

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21 January 2018

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21 January 2018

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p53 mutations, chronic hepatitis B virus infection, and aflatoxin exposure in hepatocellular carcinoma in Taiwan.

21 January 2018

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10.1038/S41598-017-03070-8

30 October 2018

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DOI

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13 June 2020

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13 June 2020

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