Plasmin overcomes resistance to prostaglandin E2 in fibrotic lung fibroblasts by reorganizing protein kinase A signaling (Q35213352)

7 August 2017

Plasmin overcomes resistance to prostaglandin E2 in fibrotic lung fibroblasts by reorganizing protein kinase A signaling (English)

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7 August 2017

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6

Marc Peters-Golden

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7 August 2017

4

Cory M Hogaboam

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7 August 2017

Katsuhide Okunishi

1

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7 August 2017

Thomas H Sisson

series ordinal

2

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7 August 2017

Steven K Huang

series ordinal

3

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7 August 2017

Richard H Simon

series ordinal

5

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7 August 2017

language of work or name

English

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publication date

27 July 2011

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Journal of Biological Chemistry

7 August 2017

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7 August 2017

286

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7 August 2017

37

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7 August 2017

32231-32243

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describes a project that uses

7 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3173171/fullTextXML

inferred from PubMed Central ID database lookup

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The antifibrotic effects of plasminogen activation occur via prostaglandin E2 synthesis in humans and mice

28 July 2018

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28 July 2018

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FcgammaRI ligation leads to a complex with BLT1 in lipid rafts that enhances rat lung macrophage antimicrobial functions

28 July 2018

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The PKARIalpha subunit of protein kinase A modulates the activation of p90RSK1 and its function

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28 July 2018

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28 July 2018

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The scaffolding protein CG-NAP/AKAP450 is a critical integrating component of the LFA-1-induced signaling complex in migratory T cells

28 July 2018

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Different effects of growth factors on proliferation and matrix production of normal and fibrotic human lung fibroblasts

28 July 2018

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Fibrotic lung fibroblasts show blunted inhibition by cAMP due to deficient cAMP response element-binding protein phosphorylation.

28 July 2018

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Leukotrienes enhance the bactericidal activity of alveolar macrophages against Klebsiella pneumoniae through the activation of NADPH oxidase

28 July 2018

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28 July 2018

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A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo

28 July 2018

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Scar/WAVE-1, a Wiskott-Aldrich syndrome protein, assembles an actin-associated multi-kinase scaffold

28 July 2018

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Specificity in the cAMP/PKA signaling pathway. Differential expression,regulation, and subcellular localization of subunits of PKA.

28 July 2018

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Characterization of a novel giant scaffolding protein, CG-NAP, that anchors multiple signaling enzymes to centrosome and the golgi apparatus

28 July 2018

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Differential inhibition and posttranslational modification of protein phosphatase 1 and 2A in MCF7 cells treated with calyculin-A, okadaic acid, and tautomycin

28 July 2018

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Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene

28 July 2018

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Biology and biochemistry of proteinases in tumor invasion.

28 July 2018

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Plasminogen activator inhibitor-1 gene-deficient mice. I. Generation by homologous recombination and characterization

28 July 2018

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Cultured lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis have a diminished capacity to synthesize prostaglandin E2 and to express cyclooxygenase-2.

28 July 2018

1 reference

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Augmentation of functional prostaglandin E levels on the respiratory epithelial surface by aerosol administration of prostaglandin E.

28 July 2018

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28 July 2018

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28 July 2018

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Suppression of LPS-induced TNF-alpha production in macrophages by cAMP is mediated by PKA-AKAP95-p105

26 September 2018

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26 September 2018

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Variable prostaglandin E2 resistance in fibroblasts from patients with usual interstitial pneumonia

26 September 2018

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Prostaglandin E(2) inhibits collagen expression and proliferation in patient-derived normal lung fibroblasts via E prostanoid 2 receptor and cAMP signaling.

26 September 2018

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Bleomycin-induced E prostanoid receptor changes alter fibroblast responses to prostaglandin E2.

26 September 2018

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Cutting edge: macrophage inhibition by cyclic AMP (cAMP): differential roles of protein kinase A and exchange protein directly activated by cAMP-1.

26 September 2018

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The plasminogen activation system reduces fibrosis in the lung by a hepatocyte growth factor-dependent mechanism

26 September 2018

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Conformational dependence of collagenase (matrix metalloproteinase-1) up-regulation by elastin peptides in cultured fibroblasts.

26 September 2018

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Thrombin stimulates fibroblast procollagen production via proteolytic activation of protease-activated receptor 1

26 September 2018

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Nuclear protein phosphatase 2A dephosphorylates protein kinase A-phosphorylated CREB and regulates CREB transcriptional stimulation

26 September 2018

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Characterization of the cellular binding site for the urokinase-type plasminogen activator

26 September 2018

1 reference

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Different Mechanisms are Involved in cAMP-Mediated Induction of mRNAs for Subunits of cAMP-Dependent Protein Kinases

26 September 2018

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American Thoracic Society. Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS)

15 November 2018

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12 December 2020

Pulmonary Arterial Hypertension

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12 December 2020

Comparison of the two classes of binding sites (A and B) of type I and type II cyclic-AMP-dependent protein kinases by using cyclic nucleotide analogs

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12 December 2020

The beta-adrenoceptor

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12 December 2020

Increased procoagulant and antifibrinolytic activities in the lungs with idiopathic pulmonary fibrosis

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12 December 2020

Clinical inhibition of the seven-transmembrane thrombin receptor (PAR1) by intravenous aprotinin during cardiothoracic surgery

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12 December 2020

Abnormalities in pathways of alveolar fibrin turnover among patients with interstitial lung disease

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12 December 2020

Identifiers

DOI

10.1074/JBC.M111.235606

1 reference

7 August 2017

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7 August 2017

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