Myocardin-related transcription factors A and B are key regulators of TGF-β1-induced fibroblast to myofibroblast differentiation (Q35417672)

8 August 2017

Myocardin-related transcription factors A and B are key regulators of TGF-β1-induced fibroblast to myofibroblast differentiation (English)

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8 August 2017

Beverly J Crider

1

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8 August 2017

George M Risinger

2

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8 August 2017

Carol J Haaksma

3

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8 August 2017

Eric W Howard

4

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8 August 2017

James J Tomasek

5

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8 August 2017

language of work or name

English

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publication date

21 July 2011

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Journal of Investigative Dermatology

8 August 2017

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8 August 2017

131

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8 August 2017

2378-2385

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8 August 2017

12

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https://scigraph.springernature.com/pub.10.1038/jid.2011.219

8 August 2017

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Smooth muscle 22 alpha maintains the differentiated phenotype of vascular smooth muscle cells by inducing filamentous actin bundling.

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Dual roles of myocardin-related transcription factors in epithelial mesenchymal transition via slug induction and actin remodeling

12 July 2018

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RPEL motifs link the serum response factor cofactor MAL but not myocardin to Rho signaling via actin binding

12 July 2018

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Reorganization of the actin cytoskeleton via transcriptional regulation of cytoskeletal/focal adhesion genes by myocardin-related transcription factors (MRTFs/MAL/MKLs).

12 July 2018

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The fibronectin synergy site modulates TGF-beta-dependent fibroblast contraction

12 July 2018

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Force activates smooth muscle alpha-actin promoter activity through the Rho signaling pathway

12 July 2018

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Diverse signaling pathways regulate fibroblast differentiation and transformation through Rho kinase activation

12 July 2018

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Focal adhesion size controls tension-dependent recruitment of alpha-smooth muscle actin to stress fibers

12 July 2018

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Regulation of alpha-smooth muscle actin expression in granulation tissue myofibroblasts is dependent on the intronic CArG element and the transforming growth factor-beta1 control element

12 July 2018

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The N-terminal Ac-EEED sequence plays a role in alpha-smooth-muscle actin incorporation into stress fibers

12 July 2018

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Myocardin/MKL family of SRF coactivators: key regulators of immediate early and muscle specific gene expression

12 July 2018

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Expression profiling of serum inducible genes identifies a subset of SRF target genes that are MKL dependent

12 July 2018

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Induction of vascular smooth muscle alpha-actin gene transcription in transforming growth factor beta1-activated myofibroblasts mediated by dynamic interplay between the Pur repressor proteins and Sp1/Smad coactivators

12 July 2018

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Normal and pathologic soft tissue remodeling: role of the myofibroblast, with special emphasis on liver and kidney fibrosis

12 July 2018

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Megakaryoblastic leukemia 1, a potent transcriptional coactivator for serum response factor (SRF), is required for serum induction of SRF target genes

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The myofibroblast in wound healing and fibrocontractive diseases

12 July 2018

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Actin dynamics control SRF activity by regulation of its coactivator MAL

12 July 2018

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Global expression profiling of fibroblast responses to transforming growth factor-beta1 reveals the induction of inhibitor of differentiation-1 and provides evidence of smooth muscle cell phenotypic switching

12 July 2018

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Potentiation of serum response factor activity by a family of myocardin-related transcription factors

12 July 2018

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The NH2-terminal peptide of alpha-smooth muscle actin inhibits force generation by the myofibroblast in vitro and in vivo

12 July 2018

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12 July 2018

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Focal adhesion features during myofibroblastic differentiation are controlled by intracellular and extracellular factors

12 July 2018

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Alpha-smooth muscle actin expression upregulates fibroblast contractile activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199034

Smooth muscle alpha-actin CArG elements coordinate formation of a smooth muscle cell-selective, serum response factor-containing activation complex

12 July 2018

1 reference

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Signal-regulated activation of serum response factor is mediated by changes in actin dynamics

12 July 2018

1 reference

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Mechanisms of myofibroblast activity and phenotypic modulation.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199034

Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts

12 July 2018

1 reference

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The myofibroblast: a key cell for wound healing and fibrocontractive diseases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199034

Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199034

Alpha-smooth muscle actin is transiently expressed by myofibroblasts during experimental wound healing.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199034

Transforming growth factor-beta in disease: the dark side of tissue repair

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199034

The role of contractile proteins in wound healing and fibrocontractive diseases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199034

Valvular myofibroblast activation by transforming growth factor-beta: implications for pathological extracellular matrix remodeling in heart valve disease.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199034

Transforming growth factor-beta 1 specifically induce proteins involved in the myofibroblast contractile apparatus

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199034

Immunofluorescence detection of the cytoskeleton and extracellular matrix in tissue and cultured cells

26 September 2018

1 reference

12 December 2020

Myofibroblasts in human granulation tissue

1 reference

12 December 2020

Myofibroblast differentiation during fibrosis

1 reference

12 December 2020

Transforming growth factor-beta1 promotes the morphological and functional differentiation of the myofibroblast

1 reference

12 December 2020

Identifiers

DOI

10.1038/JID.2011.219

1 reference

8 August 2017

1 reference

8 August 2017

1 reference