Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70 (Q33733981)

29 July 2017

Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70 (English)

1 reference

Correction for Boboila et al., Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70

29 July 2017

corrigendum / erratum

0 references

author

Michel C. Nussenzweig

10

object named as

Michel Nussenzweig

1 reference

29 July 2017

Cristian Boboila

1

1 reference

29 July 2017

Mila Jankovic

2

1 reference

29 July 2017

Catherine T Yan

3

1 reference

29 July 2017

Jing H Wang

4

1 reference

29 July 2017

Duane R Wesemann

5

1 reference

29 July 2017

Tingting Zhang

6

1 reference

29 July 2017

Alex Fazeli

7

1 reference

29 July 2017

Lauren Feldman

8

1 reference

29 July 2017

Andre Nussenzweig

9

1 reference

29 July 2017

Frederick W Alt

11

1 reference

29 July 2017

language of work or name

English

0 references

publication date

25 January 2010

1 reference

Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

6

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

29 July 2017

107

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29 July 2017

3034-3039

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29 July 2017

7

1 reference

Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4.

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

Role of the translocation partner in protection against AID-dependent chromosomal translocations

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

Mechanisms promoting translocations in editing and switching peripheral B cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switching

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

DNA-PKcs and Artemis function in the end-joining phase of immunoglobulin heavy chain class switch recombination

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

Defects in XRCC4 and KU80 differentially affect the joining of distal nonhomologous ends

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

Distinctive differences in DNA double-strand break repair between normal urothelial and urothelial carcinoma cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

IgH class switching and translocations use a robust non-classical end-joining pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

Evolution of the immunoglobulin heavy chain class switch recombination mechanism

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

Enhanced intra-switch region recombination during immunoglobulin class switch recombination in 53BP1-/- B cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

Antibody class switching mediated by yeast endonuclease-generated DNA breaks.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

ATM is required for efficient recombination between immunoglobulin switch regions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

DNA double strand break repair in human bladder cancer is error prone and involves microhomology-associated end-joining

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

The role of the non-homologous end-joining pathway in lymphocyte development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

Class-switch recombination: interplay of transcription, DNA deamination and DNA repair

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

AID: how does it aid antibody diversity?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

Impact of the KU80 pathway on NHEJ-induced genome rearrangements in mammalian cells.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

Biochemical evidence for Ku-independent backup pathways of NHEJ

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

Internal IgH class switch region deletions are position-independent and enhanced by AID expression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

Molecular mechanism of class switch recombination: linkage with somatic hypermutation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

Ku80 is required for immunoglobulin isotype switching

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

28 July 2018

Antibody class switching

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

DNA sequences at immunoglobulin switch region recombination sites

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

Class switch recombination is IgG1 specific on active and inactive IgH loci of IgG1-secreting B-cell blasts

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

Secondary genomic rearrangement events in pre-B cells: VHDJH replacement by a LINE-1 sequence and directed class switching

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840344

The block in immunoglobulin class switch recombination caused by activation-induced cytidine deaminase deficiency occurs prior to the generation of DNA double strand breaks in switch mu region

28 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915067107

Immunoglobulin heavy-chain expression and class switching in a murine leukaemia cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915067107

Circular DNA is excised by immunoglobulin class switch recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915067107

Flexibility in the order of action and in the enzymology of the nuclease, polymerases, and ligase of vertebrate non-homologous DNA end joining: relevance to cancer, aging, and the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915067107

Double-strand break repair in Ku86- and XRCC4-deficient cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915067107

Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915067107

Deletion of the IgH intronic enhancer and associated matrix-attachment regions decreases, but does not abolish, class switching at the mu locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915067107

H2AX prevents DNA breaks from progressing to chromosome breaks and translocations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915067107

AID is required for c-myc/IgH chromosome translocations in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915067107

Impact of DNA ligase IV on nonhomologous end joining pathways during class switch recombination in human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915067107

Chromosomal translocation mechanisms at intronic alu elements in mammalian cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20133803

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20133803

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0915067107

1 reference

29 July 2017

0 references

1 reference

29 July 2017

1 reference