Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta (Q33673719)

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English	Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta	scientific article

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scholarly article

1 reference

Europe PubMed Central

28 July 2017

Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta (English)

1 reference

Europe PubMed Central

28 July 2017

0 references

inflammasome complex

1 reference

based on heuristic

inferred from title

Charles A. Dinarello

7

object named as

Charles A Dinarello

1 reference

Europe PubMed Central

28 July 2017

author name string

Miyako Okamoto

1

1 reference

Europe PubMed Central

28 July 2017

Weimin Liu

2

1 reference

Europe PubMed Central

28 July 2017

Yuchun Luo

3

1 reference

Europe PubMed Central

28 July 2017

Aki Tanaka

4

1 reference

Europe PubMed Central

28 July 2017

Xiangna Cai

5

1 reference

Europe PubMed Central

28 July 2017

David A Norris

6

1 reference

Europe PubMed Central

28 July 2017

Mayumi Fujita

8

1 reference

Europe PubMed Central

28 July 2017

language of work or name

0 references

publication date

28 December 2009

1 reference

Europe PubMed Central

28 July 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

28 July 2017

285

1 reference

Europe PubMed Central

28 July 2017

6477-6488

1 reference

Europe PubMed Central

28 July 2017

9

1 reference

Europe PubMed Central

28 July 2017

Use of canakinumab in the cryopyrin-associated periodic syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

Mast cells mediate neutrophil recruitment and vascular leakage through the NLRP3 inflammasome in histamine-independent urticaria

1 reference

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21 June 2018

In vivo regulation of interleukin 1beta in patients with cryopyrin-associated periodic syndromes

1 reference

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21 June 2018

Myeloid-derived suppressor cells: linking inflammation and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

Immunological and inflammatory functions of the interleukin-1 family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

Interleukin-1 regulates the expression of sphingosine kinase 1 in glioblastoma cells

1 reference

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21 June 2018

Efficacy and safety of rilonacept (interleukin-1 Trap) in patients with cryopyrin-associated periodic syndromes: results from two sequential placebo-controlled studies

1 reference

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21 June 2018

A molecular platform in neurons regulates inflammation after spinal cord injury

1 reference

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21 June 2018

HSP90 as a marker of progression in melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

Role of chemokines in tumor growth

1 reference

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21 June 2018

A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

Dose-dependent cross-talk between the transforming growth factor-beta and interleukin-1 signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

Interleukin-1 and cancer progression: the emerging role of interleukin-1 receptor antagonist as a novel therapeutic agent in cancer treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

The inflammasome: first line of the immune response to cell stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

Interleukin-1alpha enhances the aggressive behavior of pancreatic cancer cells by regulating the alpha6beta1-integrin and urokinase plasminogen activator receptor expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

The role of interleukin 1 in growth and metastasis of human cancer xenografts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

Acquired chemoresistance in pancreatic carcinoma cells: induced secretion of IL-1beta and NO lead to inactivation of caspases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

Cryopyrin activates the inflammasome in response to toxins and ATP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

Observational study on efficacy, safety, and drug survival of anakinra in rheumatoid arthritis patients in clinical practice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

Role of nuclear factor-kappa B in melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

Blocking IL-1 in systemic inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

NALP1 is a transcriptional target for cAMP-response-element-binding protein (CREB) in myeloid leukaemia cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

Tumor stroma interactions induce chemoresistance in pancreatic ductal carcinoma cells involving increased secretion and paracrine effects of nitric oxide and interleukin-1beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

TMS1/ASC: the cancer connection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

Multifunctional interleukin-1beta promotes metastasis of human lung cancer cells in SCID mice via enhanced expression of adhesion-, invasion- and angiogenesis-related molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

IL-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

IL-1 is required for tumor invasiveness and angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

NALPs: a novel protein family involved in inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

The PAAD/PYRIN-family protein ASC is a dual regulator of a conserved step in nuclear factor kappaB activation pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

Autocrine production of interleukin 1beta confers constitutive nuclear factor kappaB activity and chemoresistance in pancreatic carcinoma cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

Inflammation and cancer: back to Virchow?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

Interleukin 1 (IL-1)-dependent melanoma hepatic metastasis in vivo; increased endothelial adherence by IL-1-induced mannose receptors and growth factor production in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

Interleukin-1 receptor blockade reduces the number and size of murine B16 melanoma hepatic metastases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

21 June 2018

IL-converting enzyme/caspase-1 inhibitor VX-765 blocks the hypersensitive response to an inflammatory stimulus in monocytes from familial cold autoinflammatory syndrome patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

30 October 2018

Pannexin-1-Mediated Recognition of Bacterial Molecules Activates the Cryopyrin Inflammasome Independent of Toll-like Receptor Signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

30 October 2018

Activation of the IL-1β-Processing Inflammasome Is Involved in Contact Hypersensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825443

30 October 2018

An inflammatory link

1 reference

https://pubmed.ncbi.nlm.nih.gov/20038581

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of interleukin-1beta in human breast carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20038581

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of interleukin-8 in tumor growth and metastasis of human melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20038581

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD11b+/Gr-1+ immature myeloid cells mediate suppression of T cells in mice bearing tumors of IL-1beta-secreting cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20038581

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive IkappaB kinase activity correlates with nuclear factor-kappaB activation in human melanoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20038581

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1beta and the autoinflammatory diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/20038581

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiapoptotic bcl-2 and bcl-xL in advanced malignant melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20038581

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inflammasome mediates UVB-induced activation and secretion of interleukin-1beta by keratinocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20038581

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo and in vitro characteristics of interleukin 6-transfected B16 melanoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20038581

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of tumor growth and metastasis of human melanoma by the CREB transcription factor family

1 reference

https://pubmed.ncbi.nlm.nih.gov/20038581

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M109.064907

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

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