Structural basis of Tie2 activation and Tie2/Tie1 heterodimerization. (Q33620110)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28396439%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

title

Structural basis of Tie2 activation and Tie2/Tie1 heterodimerization (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28396439%20AND%20SRC:MED&resulttype=core&format=json

protein heterodimerization activity

17 March 2020

main subject

1 reference

1

1 reference

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17 March 2020

author name string

Pipsa Saharinen

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28396439%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Kari Alitalo

series ordinal

3

1 reference

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17 March 2020

language of work or name

English

0 references

publication date

10 April 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28396439%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

17 March 2020

published in

1 reference

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17 March 2020

volume

114

1 reference

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17 March 2020

issue

17

1 reference

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17 March 2020

page(s)

4376-4381

1 reference

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describes a project that uses

17 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5410806/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Angiopoietin-1 is essential in mouse vasculature during development and in response to injury

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Regulated proteolytic processing of Tie1 modulates ligand responsiveness of the receptor-tyrosine kinase Tie2.

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Oligomerization and multimerization are critical for angiopoietin-1 to bind and phosphorylate Tie2.

21 June 2018

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21 June 2018

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Angiopoietin-1 and angiopoietin-2 share the same binding domains in the Tie-2 receptor involving the first Ig-like loop and the epidermal growth factor-like repeats

21 June 2018

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Angiopoietin-1 protects the adult vasculature against plasma leakage.

21 June 2018

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Angiopoietin-1 and -2 coiled coil domains mediate distinct homo-oligomerization patterns, but fibrinogen-like domains mediate ligand activity

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Loss of endothelial Tie1 receptor impairs lymphatic vessel development-brief report

21 June 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1616166114

Angiopoietins have distinct modular domains essential for receptor binding, dimerization and superclustering

21 January 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1616166114

Structure of the Extracellular Domain of Tie Receptor Tyrosine Kinases and Localization of the Angiopoietin-binding Epitope

21 January 2018

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Signal transduction by vascular endothelial growth factor receptors

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28396439

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1616166114

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28396439%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28396439%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

1 reference