Epigenetic silencing of microRNA-199b-5p is associated with acquired chemoresistance via activation of JAG1-Notch1 signaling in ovarian cancer (Q33572313)

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English	Epigenetic silencing of microRNA-199b-5p is associated with acquired chemoresistance via activation of JAG1-Notch1 signaling in ovarian cancer	scientific article

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scholarly article

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Europe PubMed Central

28 July 2017

Epigenetic silencing of microRNA-199b-5p is associated with acquired chemoresistance via activation of JAG1-Notch1 signaling in ovarian cancer (English)

1 reference

Europe PubMed Central

28 July 2017

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

object named as

David W Chan

6

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Hextan Y S Ngan

object named as

Hextan Y S Ngan

5

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author name string

Michelle X Liu

1

1 reference

Europe PubMed Central

28 July 2017

Michelle K Y Siu

2

1 reference

Europe PubMed Central

28 July 2017

Stephanie S Liu

3

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Europe PubMed Central

28 July 2017

Judy W P Yam

4

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Europe PubMed Central

28 July 2017

language of work or name

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publication date

1 February 2014

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Europe PubMed Central

28 July 2017

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Europe PubMed Central

28 July 2017

5

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Europe PubMed Central

28 July 2017

4

1 reference

Europe PubMed Central

28 July 2017

944-958

1 reference

Europe PubMed Central

28 July 2017

A microRNA signature defines chemoresistance in ovarian cancer through modulation of angiogenesis

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21 June 2018

Cisplatin selects for multidrug-resistant CD133+ cells in lung adenocarcinoma by activating Notch signaling.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011596

21 June 2018

Targeting Notch, a key pathway for ovarian cancer stem cells, sensitizes tumors to platinum therapy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011596

21 June 2018

The putative tumor suppressor miR-524-5p directly targets Jagged-1 and Hes-1 in glioma

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011596

21 June 2018

Notch signaling in developmental and tumor angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011596

21 June 2018

Upregulated JAG1 enhances cell proliferation in adrenocortical carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011596

21 June 2018

Candidate DNA methylation drivers of acquired cisplatin resistance in ovarian cancer identified by methylome and expression profiling

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21 June 2018

miRNA-34b as a tumor suppressor in estrogen-dependent growth of breast cancer cells.

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21 June 2018

DNA methylation-associated silencing of tumor-suppressor microRNAs in cancer

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21 June 2018

Identification of novel therapeutic targets in microdissected clear cell ovarian cancers

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21 June 2018

Targeting the notch ligand JAGGED1 in both tumor cells and stroma in ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011596

21 June 2018

Integrated genomic analyses of ovarian carcinoma

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011596

21 June 2018

Glypican-3 could be an effective target for immunotherapy combined with chemotherapy against ovarian clear cell carcinoma.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011596

21 June 2018

P73 regulates cisplatin-induced apoptosis in ovarian cancer cells via a calcium/calpain-dependent mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011596

21 June 2018

Notch signalling in solid tumours: a little bit of everything but not all the time

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011596

21 June 2018

Up-regulation of miR-21 mediates resistance to trastuzumab therapy for breast cancer

1 reference

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21 June 2018

MicroRNA 376c enhances ovarian cancer cell survival by targeting activin receptor-like kinase 7: implications for chemoresistance

1 reference

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21 June 2018

Plasminogen activator uPA is a direct transcriptional target of the JAG1-Notch receptor signaling pathway in breast cancer

1 reference

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21 June 2018

The effect of differentiating and apoptotic agents on notch signalling pathway in hepatoblastoma.

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21 June 2018

BRCA1-associated epigenetic regulation of p73 mediates an effector pathway for chemosensitivity in ovarian carcinoma

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21 June 2018

Identification of microRNA-21 as a biomarker for chemoresistance and clinical outcome following adjuvant therapy in resectable pancreatic cancer

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21 June 2018

MicroRNA control of signal transduction

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21 June 2018

Frequent downregulation of miR-34 family in human ovarian cancers

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21 June 2018

miR-181a and miR-630 regulate cisplatin-induced cancer cell death

1 reference

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21 June 2018

Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011596

21 June 2018

MicroRNAs in ovarian cancer biology and therapy resistance.

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21 June 2018

Down-regulation of Notch-1 and Jagged-1 inhibits prostate cancer cell growth, migration and invasion, and induces apoptosis via inactivation of Akt, mTOR, and NF-kappaB signaling pathways

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011596

21 June 2018

MicroRNAs: a complex regulatory network drives the acquisition of malignant cell phenotype

1 reference

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21 June 2018

Novel strategies for reversing platinum resistance

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21 June 2018

Enhanced expression of Annexin A4 in clear cell carcinoma of the ovary and its association with chemoresistance to carboplatin

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011596

21 June 2018

Minireview: epigenetic changes in ovarian cancer.

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21 June 2018

A network of conserved damage survival pathways revealed by a genomic RNAi screen.

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21 June 2018

The biology of ovarian cancer: new opportunities for translation

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21 June 2018

Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011596

21 June 2018

gamma-Secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011596

21 June 2018

Platinum compounds 30 years after the introduction of cisplatin: implications for the treatment of ovarian cancer

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21 June 2018

Jagged-1 and Notch3 juxtacrine loop regulates ovarian tumor growth and adhesion

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21 June 2018

Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis

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21 June 2018

Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer

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21 June 2018

MicroRNAs in malignant progression

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21 June 2018

MicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTEN

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21 June 2018

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21 June 2018

Functional coupling of p38-induced up-regulation of BiP and activation of RNA-dependent protein kinase-like endoplasmic reticulum kinase to drug resistance of dormant carcinoma cells.

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21 June 2018

The Notch pathway in ovarian carcinomas and adenomas.

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Chemotherapy for ovarian cancer: an evidence-based approach

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21 June 2018

Cancer of the ovary

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Ovarian cancer: strategies for overcoming resistance to chemotherapy

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Identification of genes that mediate sensitivity to cisplatin.

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Current treatment for ovarian cancer

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Differential induction of c-Jun NH2-terminal kinase and c-Abl kinase in DNA mismatch repair-proficient and -deficient cells exposed to cisplatin.

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21 June 2018

Loss of MKP3 mediated by oxidative stress enhances tumorigenicity and chemoresistance of ovarian cancer cells.

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31 October 2018

Inhibition of nuclear factor kappab activity by genistein is mediated via Notch-1 signaling pathway in pancreatic cancer cells

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31 October 2018

AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance.

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31 October 2018

Functional diversity among Notch1, Notch2, and Notch3 receptors

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31 October 2018

Resistance to platinum-based chemotherapy is associated with epithelial to mesenchymal transition in epithelial ovarian cancer

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31 October 2018

Genetic Interactions in Cancer Progression and Treatment

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12 December 2020

based on heuristic

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Hypermethylation of let-7a-3 in epithelial ovarian cancer is associated with low insulin-like growth factor-II expression and favorable prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24659709

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/24659709

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of Notch1 expression and activation to cisplatin-sensitivity of head and neck squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/24659709

12 December 2020

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ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a gamma-secretase inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/24659709

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.18632/ONCOTARGET.1458

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1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

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