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AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance (Q47971254)

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scientific article published on 15 April 2003

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English	AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance	scientific article published on 15 April 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/12697749

retracted paper

21 October 2016

3 references

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AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance (English)

1 reference

Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/12697749

phosphorylation

1 reference

based on heuristic

inferred from title

Domenico Coppola

4

object named as

Domenico Coppola

1 reference

Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/12697749

author name string

Zeng-Qiang Yuan

1

1 reference

Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/12697749

Richard I Feldman

2

1 reference

Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/12697749

Gene E Sussman

3

1 reference

Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/12697749

Santo V Nicosia

5

1 reference

Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/12697749

Jin Q Cheng

6

1 reference

Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/12697749

publication date

15 April 2003

1 reference

Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/12697749

language of work or name

0 references

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/12697749

278

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Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/12697749

26

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PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/12697749

23432-23440

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Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/12697749

Ovarian cancer: progress and continuing controversies in management

1 reference

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21 January 2018

Augmentation of adriamycin, melphalan, and cisplatin cytotoxicity in drug-resistant and -sensitive human ovarian carcinoma cell lines by buthionine sulfoximine mediated glutathione depletion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302674200

21 January 2018

High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302674200

21 January 2018

Acquired cisplatin resistance in human ovarian cancer cells is associated with enhanced repair of cisplatin-DNA lesions and reduced drug accumulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302674200

21 January 2018

Introduction of wild-type p53 in a human ovarian cancer cell line not expressing endogenous p53

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302674200

21 January 2018

The phosphoinositide 3-kinase pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302674200

21 January 2018

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

1 reference

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21 January 2018

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

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21 January 2018

The activation of protein kinase B by H2O2 or heat shock is mediated by phosphoinositide 3-kinase and not by mitogen-activated protein kinase-activated protein kinase-2

1 reference

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21 January 2018

Mechanism of activation and function of protein kinase B.

1 reference

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21 January 2018

Interleukin-3-Induced Phosphorylation of BAD Through the Protein Kinase Akt

1 reference

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21 January 2018

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302674200

21 January 2018

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

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21 January 2018

AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas

1 reference

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21 January 2018

Transforming activity and mitosis-related expression of the AKT2 oncogene: evidence suggesting a link between cell cycle regulation and oncogenesis

1 reference

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21 January 2018

The phosphoinositide 3-OH kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced apoptosis

1 reference

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21 January 2018

Inhibition of JNK by cellular stress- and tumor necrosis factor alpha-induced AKT2 through activation of the NF kappa B pathway in human epithelial Cells

1 reference

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21 January 2018

Enhanced ROS production in oncogenically transformed cells potentiates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase activation and sensitization to genotoxic stress

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302674200

21 January 2018

Cisplatin induces a persistent activation of JNK that is related to cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302674200

21 January 2018

The stress-activated protein kinase pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302674200

21 January 2018

BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302674200

21 January 2018

Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302674200

21 January 2018

ASK1 is essential for JNK/SAPK activation by TRAF2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302674200

21 January 2018

Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302674200

21 January 2018

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302674200

21 January 2018

Reactive Oxygen Species- and Dimerization-induced Activation of Apoptosis Signal-regulating Kinase 1 in Tumor Necrosis Factor-α Signal Transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302674200

21 January 2018

Microtubule-interfering Agents Activate c-Jun N-terminal Kinase/Stress-activated Protein Kinase through Both Ras and Apoptosis Signal-regulating Kinase Pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302674200

21 January 2018

ASK1 mediates apoptotic cell death induced by genotoxic stress.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302674200

21 January 2018

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302674200

21 January 2018

AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302674200

21 January 2018

Apoptosis-promoting gene (bax) transfer potentiates sensitivity of squamous cell carcinoma to cisplatin in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302674200

21 January 2018

Damage-induced Bax N-terminal change, translocation to mitochondria and formation of Bax dimers/complexes occur regardless of cell fate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302674200

21 January 2018

The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302674200

21 January 2018

The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302674200

21 January 2018

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302674200

21 January 2018

Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302674200

21 January 2018

Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling.

1 reference

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21 January 2018

Inhibition of JNK activation through NF-κB target genes

1 reference

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21 January 2018

Cisplatin-induced apoptosis in auditory cells: role of death receptor and mitochondrial pathways

1 reference

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21 January 2018

Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

1 reference

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21 January 2018

Spontaneous and drug-induced apoptosis is mediated by conformational changes of Bax and Bak in B-cell chronic lymphocytic leukemia

1 reference

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21 January 2018

Identification of novel isoforms of the BH3 domain protein Bim which directly activate Bax to trigger apoptosis

1 reference

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21 January 2018

The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302674200

21 January 2018

JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302674200

21 January 2018

Lack of c-Jun activity increases survival to cisplatin

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1074/JBC.M302674200

Frequent activation of AKT2 and induction of apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1074/JBC.M302674200

Identifiers

10.1074/JBC.M302674200

1 reference

Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/12697749

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 February 2018

http://europepmc.org/abstract/MED/12697749

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