Pivotal effects of phosphodiesterase inhibitors on myocyte contractility and viability in normal and ischemic hearts (Q33552229)

28 July 2017

1 reference

title

Pivotal effects of phosphodiesterase inhibitors on myocyte contractility and viability in normal and ischemic hearts (English)

1 reference

28 July 2017

Lei Xi

2

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author name string

Yuan James Rao

series ordinal

1

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28 July 2017

8 December 2008

1 reference

Acta Pharmacologica Sinica

28 July 2017

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28 July 2017

30

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28 July 2017

1

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28 July 2017

1-24

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https://scigraph.springernature.com/pub.10.1038/aps.2008.1

28 July 2017

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cites work

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Sildenafil and cardiomyocyte-specific cGMP signaling prevent cardiomyopathic changes associated with dystrophin deficiency

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14 July 2018

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Adenosine A(1) receptor mediates delayed cardioprotective effect of sildenafil in mouse.

14 July 2018

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Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility

14 July 2018

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cAMP and cGMP signaling cross-talk: role of phosphodiesterases and implications for cardiac pathophysiology

14 July 2018

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Modulation of the ryanodine receptor and intracellular calcium

14 July 2018

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Phosphodiesterase regulation of nitric oxide signaling

14 July 2018

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cAMP-Specific phosphodiesterase-4 enzymes in the cardiovascular system: a molecular toolbox for generating compartmentalized cAMP signaling

14 July 2018

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Myocardial phosphodiesterases and regulation of cardiac contractility in health and cardiac disease.

14 July 2018

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Regulation of phosphodiesterase 3 and inducible cAMP early repressor in the heart

14 July 2018

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14 July 2018

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Novel targets for treating heart and muscle disease: stabilizing ryanodine receptors and preventing intracellular calcium leak

14 July 2018

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Review of current and investigational pharmacologic agents for acute heart failure syndromes

14 July 2018

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Beta-adrenergic pathways in human heart failure

14 July 2018

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Phosphodiesterase 4 inhibitors for the treatment of asthma and COPD

14 July 2018

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Cardioprotection with sildenafil: implications for clinical practice

14 July 2018

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Sildenafil and vardenafil but not nitroglycerin limit myocardial infarction through opening of mitochondrial K(ATP) channels when administered at reperfusion following ischemia in rabbits

14 July 2018

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Rolipram: a specific phosphodiesterase 4 inhibitor with potential antipsychotic activity.

14 July 2018

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Effect of alpha1-adrenergic receptors in cardiac pathophysiology

14 July 2018

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Compartmentation of cyclic nucleotide signaling in the heart: the role of cyclic nucleotide phosphodiesterases.

14 July 2018

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Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use

14 July 2018

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Sildenafil: from angina to erectile dysfunction to pulmonary hypertension and beyond.

14 July 2018

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Pimobendan in heart failure therapy--a silver bullet?

14 July 2018

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Ser-2030, but not Ser-2808, is the major phosphorylation site in cardiac ryanodine receptors responding to protein kinase A activation upon beta-adrenergic stimulation in normal and failing hearts.

14 July 2018

1 reference

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Phospholemman inhibition of the cardiac Na+/Ca2+ exchanger. Role of phosphorylation

14 July 2018

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Phosphodiesterase type 4 expression and anti-proliferative effects in human pulmonary artery smooth muscle cells

14 July 2018

1 reference

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Ryanodine receptor/calcium release channel PKA phosphorylation: a critical mediator of heart failure progression

14 July 2018

1 reference

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Sildenafil citrate therapy for pulmonary arterial hypertension

14 July 2018

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A new chemical tool for exploring the physiological function of the PDE2 isozyme

14 July 2018

1 reference

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The potential use of type-5 phosphodiesterase inhibitors in coronary artery bypass graft surgery

14 July 2018

1 reference

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Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias

14 July 2018

1 reference

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A positive feedback loop of phosphodiesterase 3 (PDE3) and inducible cAMP early repressor (ICER) leads to cardiomyocyte apoptosis.

14 July 2018

1 reference

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The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways.

14 July 2018

1 reference

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Modulating sarco(endo)plasmic reticulum Ca2+ ATPase 2 (SERCA2) activity: cell biological implications.

14 July 2018

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Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

RNA silencing identifies PDE4D5 as the functionally relevant cAMP phosphodiesterase interacting with beta arrestin to control the protein kinase A/AKAP79-mediated switching of the beta2-adrenergic receptor to activation of ERK in HEK293B2 cells.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Pharmacological preconditioning with sildenafil: Basic mechanisms and clinical implications

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Functional role of phosphodiesterase 3 in cardiomyocyte apoptosis: implication in heart failure

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Phosphodiesterase-5 inhibition with sildenafil attenuates cardiomyocyte apoptosis and left ventricular dysfunction in a chronic model of doxorubicin cardiotoxicity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Regulation of cardiac contractile function by troponin I phosphorylation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Splice variants of the cyclic nucleotide phosphodiesterase PDE4D are differentially expressed and regulated in rat tissue.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Structural based insights into the role of troponin in cardiac muscle pathophysiology

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Putting the brakes on cardiac hypertrophy: exploiting the NO-cGMP counter-regulatory system

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Tumor necrosis factor-alpha-dependent expression of phosphodiesterase 2: role in endothelial hyperpermeability

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Phosphodiesterase 4D is required for beta2 adrenoceptor subtype-specific signaling in cardiac myocytes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Reduction of infarct size and postischemic inflammation from ATL-146e, a highly selective adenosine A2A receptor agonist, in reperfused canine myocardium

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Inhibition of phosphodiesterase 2 increases neuronal cGMP, synaptic plasticity and memory performance

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

In vivo and in vitro analysis of cardiac troponin I phosphorylation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Vardenafil preclinical trial data: potency, pharmacodynamics, pharmacokinetics, and adverse events

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Mechanisms of action of PDE5 inhibition in erectile dysfunction

14 July 2018

1 reference

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Altered cAMP-mediated signalling and its role in the pathogenesis of dilated cardiomyopathy

14 July 2018

1 reference

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Diminished Inotropic Response to Amrinone in Ventricular Myocytes from Myopathic Hamsters Is Linked to Depression of High-Gain Ca2+-Induced Ca2+ Release

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Cardioprotection with phosphodiesterase-5 inhibition--a novel preconditioning strategy.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Sildenafil (Viagra) reduces arrhythmia severity during ischaemia 24 h after oral administration in dogs

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Regulation of L-type Ca2+ channels in the heart: overview of recent advances

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

What is the role of beta-adrenergic signaling in heart failure?

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Cardiovascular effects of tadalafil

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

The unique amino-terminal region of the PDE4D5 cAMP phosphodiesterase isoform confers preferential interaction with beta-arrestins

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Regulation and organization of adenylyl cyclases and cAMP.

14 July 2018

1 reference

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Cyclic AMP compartmentation due to increased cAMP-phosphodiesterase activity in transgenic mice with a cardiac-directed expression of the human adenylyl cyclase type 8 (AC8).

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Therapeutic potential of phosphodiesterase 5 inhibition for cardiovascular disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Phospholamban: a crucial regulator of cardiac contractility

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Protein kinase A hyperphosphorylation increases basal current but decreases beta-adrenergic responsiveness of the sarcolemmal Na+-Ca2+ exchanger in failing pig myocytes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Sildenafil induces delayed preconditioning through inducible nitric oxide synthase-dependent pathway in mouse heart.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

PDE5 is converted to an activated state upon cGMP binding to the GAF A domain

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

beta-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from Gs to Gi

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Dancing with different partners: protein kinase a phosphorylation of seven membrane-spanning receptors regulates their G protein-coupling specificity.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Differential effects of amrinone and milrinone upon myocardial inflammatory signaling.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Effects of sildenafil citrate (viagra) on cardiac repolarization and on autonomic control in subjects with chronic heart failure

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Cilostazol (pletal): a dual inhibitor of cyclic nucleotide phosphodiesterase type 3 and adenosine uptake

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Interplay between inhibition of adenosine uptake and phosphodiesterase type 3 on cardiac function by cilostazol, an agent to treat intermittent claudication

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Cardiac phosphodiesterase 5 (cGMP-specific) modulates beta-adrenergic signaling in vivo and is down-regulated in heart failure

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Cyclic GMP regulation of the L-type Ca(2+) channel current in human atrial myocytes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Sildenafil citrate (Viagra) does not exacerbate myocardial ischemia in canine models of coronary artery stenosis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Myomegalin is a novel protein of the golgi/centrosome that interacts with a cyclic nucleotide phosphodiesterase

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Cyclic nucleotide phosphodiesterase type 5 activity limits blood flow to hypoperfused myocardium during exercise

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Regulation of cardiac L-type calcium channels by protein kinase A and protein kinase C.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

cGMP-dependent protein kinase mediates stimulation of L-type calcium current by cGMP in rabbit atrial cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Regulation and function of the cyclic nucleotide phosphodiesterase (PDE3) gene family

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Inhibition of adenosine uptake and augmentation of ischemia-induced increase of interstitial adenosine by cilostazol, an agent to treat intermittent claudication

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Prophylactic amrinone for weaning from cardiopulmonary bypass.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Paracrine and autocrine effects of nitric oxide on myocardial function

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Potent effects of novel anti-platelet aggregatory cilostamide analogues on recombinant cyclic nucleotide phosphodiesterase isozyme activity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Characterization of the cyclic nucleotide phosphodiesterase subtypes involved in the regulation of the L-type Ca2+ current in rat ventricular myocytes.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Activation of distinct cAMP-dependent and cGMP-dependent pathways by nitric oxide in cardiac myocytes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Guanylate cyclase and the .NO/cGMP signaling pathway

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Effects of sildenafil citrate on human hemodynamics.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Does tumor necrosis factor-alpha (TNF-alpha) contribute to myocardial reperfusion injury in anesthetized rats?

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Binding of cGMP to both allosteric sites of cGMP-binding cGMP-specific phosphodiesterase (PDE5) is required for its phosphorylation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

cGMP-stimulated cyclic nucleotide phosphodiesterase regulates the basal calcium current in human atrial myocytes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Structure, localization, and regulation of cGMP-inhibited phosphodiesterase (PDE3)

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

A placebo-controlled trial verifying the efficacy of milrinone in weaning high-risk patients from cardiopulmonary bypass.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Effect of pimobendan on exercise capacity in patients with heart failure: main results from the Pimobendan in Congestive Heart Failure (PICO) trial

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Phosphorylation and activation of a cAMP-specific phosphodiesterase by the cAMP-dependent protein kinase. Involvement of serine 54 in the enzyme activation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Isozyme selective inhibition of cGMP-stimulated cyclic nucleotide phosphodiesterases by erythro-9-(2-hydroxy-3-nonyl) adenine

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Rate-limiting steps in the beta-adrenergic stimulation of cardiac calcium current

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Use of milrinone in cardiac surgical patients

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

The structure of a bovine lung cGMP-binding, cGMP-specific phosphodiesterase deduced from a cDNA clone.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Nitric oxide regulates cardiac Ca2+ current. Involvement of cGMP-inhibited and cGMP-stimulated phosphodiesterases through guanylyl cyclase activation.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

A randomized comparison of intravenous amrinone versus dobutamine in older patients with decompensated congestive heart failure.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Nitric oxide regulates the calcium current in isolated human atrial myocytes.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

The effects of phosphorylation of cardiac troponin-I on its interactions with actin and cardiac troponin-C.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Characterization of a novel cGMP binding protein from rat lung

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Withdrawal of long-term amrinone therapy in patients with congestive heart failure: a placebo controlled trial

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Is phosphodiesterase inhibition a new mechanism of antidepressant action? A double blind double-dummy study between rolipram and desipramine in hospitalized major and/or endogenous depressives

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Effects of amrinone and milrinone on calcium influx into the myocardium

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

LY195115: a potent, selective inhibitor of cyclic nucleotide phosphodiesterase located in the sarcoplasmic reticulum.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Subclasses of cyclic AMP-specific phosphodiesterase in left ventricular muscle and their involvement in regulating myocardial contractility

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

The effect of extracellular Ca2+ and related ions on the cardiac action of milrinone.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Mechanism of the positive inotropic effect of milrinone in cultured embryonic chick ventricular cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Opposite effects of cyclic GMP and cyclic AMP on Ca2+ current in single heart cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Pharmacology of the bipyridines: amrinone and milrinone.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Comparison of intravenous amrinone and dobutamine in congestive heart failure due to idiopathic dilated cardiomyopathy

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Effect of amrinone in the working rat heart: influence of ischaemic damage, adenosine and calcium.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

In-patient major depression: is rolipram as effective as amitriptyline?

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Effects of variable dose milrinone in patients with low cardiac output after cardiac surgery. European Multicenter Trial Group.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Effect of oral milrinone on mortality in severe chronic heart failure. The PROMISE Study Research Group

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Cellular distribution of phosphodiesterase isoforms in rat cardiac tissue

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Involvement of Rolipram-Sensitive Cyclic AMP Phosphodiesterase in the Regulation of Cardiac Contraction

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Regulation of calcium current by low-Km cyclic AMP phosphodiesterases in cardiac cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Differential effects of Ro 20-1724 and isobutylmethylxanthine on the basal force of contraction and β-adrenoceptor-mediated response in the rat ventricular myocardium

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Potentiation by cyclic GMP of beta-adrenergic effect on Ca2+ current in guinea-pig ventricular cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Signal transduction by cGMP in heart.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Phosphodiesterase inhibitors and the cardiac sarcoplasmic reticulum calcium release channel: differential effects of milrinone and enoximone.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Effects of zaprinast and rolipram on platelet aggregation and arrhythmias following myocardial ischaemia and reperfusion in anaesthetized rabbits

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Inhibition of granulocyte cAMP-phosphodiesterase by rolipram in vivo is not sufficient to protect the canine myocardium from reperfusion injury

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Selective inhibitor of platelet cyclic adenosine monophosphate phosphodiesterase, cilostamide, inhibits platelet aggregation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Inducible cAMP early repressor (ICER) is a negative-feedback regulator of cardiac hypertrophy and an important mediator of cardiac myocyte apoptosis in response to beta-adrenergic receptor stimulation.

14 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Myocardial contractile response to nitric oxide and cGMP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Serine 68 of phospholemman is critical in modulation of contractility, [Ca2+]i transients, and Na+/Ca2+ exchange in adult rat cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Protein kinase A mediated modulation of acto-myosin kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

cGMP-dependent protein kinase in regulation of basal tone and in nitroglycerin- and nitric-oxide-induced relaxation in porcine coronary artery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Hypercontractile female hearts exhibit increased S-nitrosylation of the L-type Ca2+ channel alpha1 subunit and reduced ischemia/reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Differential role of S-nitrosylation and the NO-cGMP-PKG pathway in cardiac contractility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Isoforms of cyclic nucleotide phosphodiesterase PDE3 and their contribution to cAMP hydrolytic activity in subcellular fractions of human myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

PI3Kγ Modulates the Cardiac Response to Chronic Pressure Overload by Distinct Kinase-Dependent and -Independent Effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

High and low gain switches for regulation of cAMP efflux concentration: distinct roles for particulate GC- and soluble GC-cGMP-PDE3 signaling in rabbit atria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Control of renin secretion from rat juxtaglomerular cells by cAMP-specific phosphodiesterases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

A comparison of three phosphodiesterase type III inhibitors on mechanical and metabolic function in guinea pig isolated hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Contractile responses to selective phosphodiesterase inhibitors following chronic beta-adrenoreceptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Contribution of phosphodiesterase isozymes to the regulation of the L-type calcium current in human cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

New milrinone analogues: in vitro study of structure-activity relationships for positive inotropic effect, antagonism towards endogenous adenosine, and inhibition of cardiac type III phosphodiesterase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Effects of rolipram, pimobendan and zaprinast on ischaemia-induced dysrhythmias and on ventricular cyclic nucleotide content in the anaesthetized rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Cardioprotective effect afforded by transient exposure to phosphodiesterase III inhibitors: the role of protein kinase A and p38 mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Milrinone administered before ischemia or just after reperfusion, attenuates myocardial stunning in anesthetized swine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Improved survival with simendan after experimental myocardial infarction in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Repetitive preischemic infusion of phosphodiesterase III inhibitor olprinone elicits cardioprotective effects in the failing heart after myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

The cardioprotective effect of a statin and cilostazol combination: relationship to Akt and endothelial nitric oxide synthase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Short-term intravenous milrinone for acute exacerbation of chronic heart failure: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Heart failure etiology and response to milrinone in decompensated heart failure: results from the OPTIME-CHF study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Effects of amrinone on myocardial energy metabolism and hemodynamics in patients with severe congestive heart failure due to coronary artery disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Effects of a phosphodiesterase III inhibitor on circulating blood volume after cardiopulmonary bypass.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Inotropic responses to phosphodiesterase inhibitors in cardiac hypertrophy in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Enoximone in cardiac arrest caused by propranolol: two case reports.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Fluorescence resonance energy transfer-based analysis of cAMP dynamics in live neonatal rat cardiac myocytes reveals distinct functions of compartmentalized phosphodiesterases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Interaction of metoprolol with lorazepam and bromazepam

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Rolipram reduces the inotropic tachyphylaxis of glucagon in rat ventricular myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

An overview of the pharmacokinetics of cilomilast (Ariflo), a new, orally active phosphodiesterase 4 inhibitor, in healthy young and elderly volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Cilomilast: pharmacokinetic and pharmacodynamic interactions with digoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

The influence of phosphodiesterase inhibitor, rolipram, on hemodynamics in lipopolysaccharide-treated rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Type IV phosphodiesterase inhibition improves cardiac contractility in endotoxemic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Protection against doxorubicin cardiomyopathy in rats: role of phosphodiesterase inhibitors type 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Phosphodiesterase-5 inhibitor sildenafil preconditions adult cardiac myocytes against necrosis and apoptosis. Essential role of nitric oxide signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Compartmentalization of cardiac beta-adrenergic inotropy modulation by phosphodiesterase type 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Expression of three isoforms of cGMP-binding cGMP-specific phosphodiesterase (PDE5) in human penile cavernosum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Specific cGMP binding by the cGMP binding domains of cGMP-binding cGMP specific phosphodiesterase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Regulation of cGMP-specific phosphodiesterase (PDE5) phosphorylation in smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

cGMP catabolism by phosphodiesterase 5A regulates cardiac adrenergic stimulation by NOS3-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Cardiac electrophysiologic and hemodynamic effects of sildenafil, a PDE5 inhibitor, in anesthetized dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Sildenafil inhibits beta-adrenergic-stimulated cardiac contractility in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Sympathetic activation by sildenafil.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Effects of sildenafil (viagra) on human myocardial contractility, in vitro arrhythmias, and tension of internal mammaria arteries and saphenous veins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Sildenafil citrate does not affect cardiac contractility in human or dog heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Molecular mechanisms of cardiostimulatory effects of sildenafil

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

The phosphodiesterase-5 inhibitor tadalafil reduces myocardial infarct size

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Sildenafil (Viagra) induces powerful cardioprotective effect via opening of mitochondrial K(ATP) channels in rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Sildenafil citrate (viagra) induces cardioprotective effects after ischemia/reperfusion injury in infant rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Essential role of mitochondrial Ca2+-activated and ATP-sensitive K+ channels in sildenafil-induced late cardioprotection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Vardenafil: a novel type 5 phosphodiesterase inhibitor reduces myocardial infarct size following ischemia/reperfusion injury via opening of mitochondrial K(ATP) channels in rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Effect of sildenafil on reperfusion function, infarct size, and cyclic nucleotide levels in the isolated rat heart model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Enhanced cardioprotection against ischemia-reperfusion injury with combining sildenafil with low-dose atorvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Protein kinase C plays an essential role in sildenafil-induced cardioprotection in rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Sildenafil-mediated acute cardioprotection is independent of the NO/cGMP pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Remote ischemic preconditioning provides early and late protection against endothelial ischemia-reperfusion injury in humans: role of the autonomic nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Phosphodiesterase type 5 as a target for the treatment of hypoxia-induced pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Oral sildenafil is an effective and specific pulmonary vasodilator in patients with pulmonary arterial hypertension: comparison with inhaled nitric oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

DA-8159, a potent cGMP phosphodiesterase inhibitor, attenuates monocrotaline-induced pulmonary hypertension in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

DA-8159, a new PDE5 inhibitor, attenuates the development of compensatory right ventricular hypertrophy in a rat model of pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Sildenafil selectively inhibits acute pulmonary embolism-induced pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

The effect of sildenafil on human vascular function, platelet activation, and myocardial ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Acute and prolonged effects of sildenafil on brachial artery flow-mediated dilatation in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Sildenafil prevents endothelial dysfunction induced by ischemia and reperfusion via opening of adenosine triphosphate-sensitive potassium channels: a human in vivo study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Effect of PDE5 inhibition on coronary hemodynamics in pacing-induced heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Acute phosphodiesterase 5 inhibition mimics hemodynamic effects of B-type natriuretic peptide and potentiates B-type natriuretic peptide effects in failing but not normal canine heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Sildenafil effects on exercise, neurohormonal activation, and erectile dysfunction in congestive heart failure: a double-blind, placebo-controlled, randomized study followed by a prospective treatment for erectile dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Effect of sildenafil on cardiac performance in patients with heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Vinpocetine-induced stimulation of calcium-activated potassium currents in rat pituitary GH3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

The role of cyclic nucleotide phosphodiesterases in the regulation of adipocyte lipolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Compartmentalized phosphodiesterase-2 activity blunts beta-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Two inotropes with different mechanisms of action: contractile, PDE-inhibitory and direct myofibrillar effects of levosimendan and enoximone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Diabetes abolishes sildenafil-induced cGMP-dependent protein kinase-I expression and cardioprotection

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Differences in hemodynamic and oxygenation responses to three different phosphodiesterase-5 inhibitors in patients with pulmonary arterial hypertension: a randomized prospective study

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Immediate and Long-term Hemodynamic and Clinical Effects of Sildenafil in Patients With Pulmonary Arterial Hypertension Receiving Vasodilator Therapy

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Intravenous sildenafil is a potent pulmonary vasodilator in children with congenital heart disease

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Cardioprotection with sildenafil, a selective inhibitor of cyclic 3',5'-monophosphate-specific phosphodiesterase 5.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Comparison of enoximone, amrinone, or levosimendan enriched St. Thomas' hospital cardioplegic solutions used for myocardial preservation in isolated guinea pig hearts

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Effects of pimobendan on adverse cardiac events and physical activities in patients with mild to moderate chronic heart failure: the effects of pimobendan on chronic heart failure study (EPOCH study).

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Enhanced cAMP-induced nitric oxide-dependent coronary dilation during myocardial stunning in conscious pigs.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

A bolus dose of 1.5 mg/kg amrinone effectively improves low cardiac output state following separation from cardiopulmonary bypass in cardiac surgical patients.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Protection of the hypoxic myocardium by the bispyridine derivatives AWD 122-14 and milrinone: studies on isolated, working right rabbit hearts

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006539

Effect of 1-Year Treatment with Roflumilast in Severe Chronic Obstructive Pulmonary Disease

31 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Glucagon stimulates the cardiac Ca2+ current by activation of adenylyl cyclase and inhibition of phosphodiesterase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

Effects of low-dose milrinone on weaning from cardiopulmonary bypass and after in patients with mitral stenosis and pulmonary hypertension

21 January 2018

1 reference

12 December 2020

Structural and functional features in human PDE5A1 regulatory domain that provide for allosteric cGMP binding, dimerization, and regulation

1 reference

12 December 2020

Milrinone combined with vasopressin improves cardiac index after cardiopulmonary resuscitation in a pig model of myocardial infarction

1 reference

12 December 2020

A comparison of oral milrinone, digoxin, and their combination in the treatment of patients with chronic heart failure

1 reference

12 December 2020

Acute type 5 phosphodiesterase inhibition with sildenafil enhances flow-mediated vasodilation in patients with chronic heart failure

1 reference

12 December 2020

Effects of sildenafil on cAMP and cGMP levels in isolated human cavernous and cardiac tissue

1 reference

12 December 2020

Oral amrinone in refractory congestive heart failure

1 reference

12 December 2020

Implication of Cyclic AMP in the Positive Inotropic Effects of Cyclic GMP-Inhibited Cyclic AMP Phosphodiesterase Inhibitors on Guinea Pig Isolated Left Atria

1 reference

12 December 2020

Positive and negative inotropic effects of NO donors in atrial and ventricular fibres of the frog heart

1 reference

12 December 2020

8-bromo-cGMP reduces the myofilament response to Ca2+ in intact cardiac myocytes

1 reference

12 December 2020

Amrinone preconditioning in the isolated perfused rabbit heart

1 reference

12 December 2020

Tissue distribution of phosphodiesterase families and the effects of sildenafil on tissue cyclic nucleotides, platelet function, and the contractile responses of trabeculae carneae and aortic rings in vitro

1 reference

12 December 2020

Relation of positive inotropic and chronotropic effects of pimobendan, UD-CG 212 Cl, milrinone and other phosphodiesterase inhibitors to phosphodiesterase III inhibition in guinea-pig heart

1 reference

12 December 2020

Effects of pimobendan and EGIS 9377, cardiotonic agents, and OG-VI, a nucleoside-nucleotide mixture, administered during reperfusion after ischemia on stunned myocardium in dogs

1 reference

12 December 2020

Heart failure-associated alterations in troponin I phosphorylation impair ventricular relaxation-afterload and force-frequency responses and systolic function

1 reference

12 December 2020

Hemodynamic effects of sildenafil in men with severe coronary artery disease

1 reference

12 December 2020

Isoforms of cyclic nucleotide phosphodiesterase PDE3A in cardiac myocytes

1 reference

12 December 2020

Troponin phosphorylation and regulatory function in human heart muscle: dephosphorylation of Ser23/24 on troponin I could account for the contractile defect in end-stage heart failure

1 reference

12 December 2020

Clinical experience of milrinone as a pharmacological bridge to heart transplantation

1 reference

12 December 2020

Subaortic obstruction after sildenafil in a patient with hypertrophic cardiomyopathy

1 reference

12 December 2020

Dose-proportional intraindividual single- and repeated-dose pharmacokinetics of roflumilast, an oral, once-daily phosphodiesterase 4 inhibitor

1 reference

12 December 2020

Effect of levosimendan and milrinone on regional myocardial ischemia/reperfusion-induced arrhythmias in dogs

1 reference

12 December 2020

Effect of milrinone on left ventricular relaxation and Ca(2+) uptake function of cardiac sarcoplasmic reticulum

1 reference

12 December 2020

cGMP-independent inotropic effects of nitric oxide and peroxynitrite donors: potential role for nitrosylation

1 reference

12 December 2020

Long-term amrinone therapy in patients with severe heart failure: drug-dependent hemodynamic benefits despite progression of disease

1 reference

12 December 2020

Role of cyclic nucleotide phosphodiesterases in ischemic preconditioning

1 reference

12 December 2020

Oral amrinone for the treatment of chronic congestive heart failure: results of a multicenter randomized double-blind and placebo-controlled withdrawal study

1 reference

12 December 2020

Long-term oral administration of amrinone for congestive heart failure: lack of efficacy in a multicenter controlled trial

1 reference

12 December 2020

Comparison of cyclic nucleotide phosphodiesterase isoenzymes in rat and rabbit ventricular myocardium: positive inotropic and phosphodiesterase inhibitory effects of Org 30029, milrinone and rolipram

1 reference

12 December 2020

Multicenter trial of oral enoximone in patients with moderate to moderately severe congestive heart failure. Lack of benefit compared with placebo. Enoximone Multicenter Trial Group

1 reference

12 December 2020

Phosphorylation of phosphodiesterase-5 by cyclic nucleotide-dependent protein kinase alters its catalytic and allosteric cGMP-binding activities

1 reference

12 December 2020

Low increase in cGMP induced by organic nitrates and nitrovasodilators improves contractile response of rat ventricular myocytes

1 reference

12 December 2020

Selective inhibition of cyclic nucleotide phosphodiesterases of human, bovine and rat aorta

1 reference

12 December 2020

Effects of type IV phosphodiesterase inhibition on cardiac function in the presence and absence of catecholamines

1 reference

12 December 2020

Sildenafil reduces cardiovascular remodeling associated with hypertensive cardiomyopathy in NOS inhibitor-treated rats

1 reference

12 December 2020

Amrinone reduces ischaemia-reperfusion injury in rat heart

1 reference

12 December 2020

[The effect of milrinone for the shock patients after cardiac surgery]

1 reference

12 December 2020

Effect of combining phosphodiesterase III inhibitors with St Thomas Hospital's solution used as transplantation preservative solution in isolated rat hearts

1 reference

12 December 2020

Modulation of cardiac sarcoplasmic reticulum calcium release by aenosine: a protein kinase C- dependent pathway

1 reference

12 December 2020

Role of phosphodiesterase type 3A and 3B in regulating platelet and cardiac function using subtype-selective knockout mice

1 reference

12 December 2020

Effects of pimobendan on the L-type Ca2+ current and developed tension in guinea-pig ventricular myocytes and papillary muscle: comparison with IBMX, milrinone, and cilostazol

1 reference

12 December 2020

Low-dose enoximone improves exercise capacity in chronic heart failure. Enoximone Study Group

1 reference

12 December 2020

Catheter ablation for treatment of tachyarrhythmias: present role and potential promise

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

7 January 2021

inferred from DOI database lookup

Intramural hematoma in acute aortic syndrome: more than one variant of dissection?

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2008.1

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/APS.2008.1

1 reference

PubMed ID

19060915

Dimensions Publication ID

28 July 2017

0 references

1 reference

28 July 2017

1 reference

PubMed ID

19060915