Myelodysplastic syndromes: Contemporary review and how we treat (Q33429195)

26 July 2017

title

Myelodysplastic syndromes: Contemporary review and how we treat (English)

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26 July 2017

3

Ayalew Tefferi

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26 July 2017

Naseema Gangat

1

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26 July 2017

Mrinal M Patnaik

series ordinal

2

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26 July 2017

publication date

1 January 2016

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American Journal of Hematology

26 July 2017

published in

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26 July 2017

volume

91

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26 July 2017

issue

1

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26 July 2017

page(s)

76-89

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The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes

26 July 2017

cites work

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The epidemiology of myelodysplastic syndromes

21 January 2018

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Revised international prognostic scoring system for myelodysplastic syndromes

21 January 2018

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Proposal for a new risk model in myelodysplastic syndrome that accounts for events not considered in the original International Prognostic Scoring System

21 January 2018

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Differential prognostic effect of IDH1 versus IDH2 mutations in myelodysplastic syndromes: a Mayo Clinic study of 277 patients

21 January 2018

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SF3B1 mutations are prevalent in myelodysplastic syndromes with ring sideroblasts but do not hold independent prognostic value

21 January 2018

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Recurrent DNMT3A mutations in patients with myelodysplastic syndromes

21 January 2018

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Frequent pathway mutations of splicing machinery in myelodysplasia

21 January 2018

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Clinical effect of point mutations in myelodysplastic syndromes

21 January 2018

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Validation of a prognostic model and the impact of mutations in patients with lower-risk myelodysplastic syndromes

21 January 2018

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Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study

21 January 2018

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Decitabine improves patient outcomes in myelodysplastic syndromes: results of a phase III randomized study

21 January 2018

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Efficacy of lenalidomide in myelodysplastic syndromes

21 January 2018

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Clinical and biological implications of driver mutations in myelodysplastic syndromes

21 January 2018

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Dyskeratosis congenita in all its forms

21 January 2018

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Down myeloid disorders: a paradigm for childhood preleukaemia and leukaemia and insights into normal megakaryopoiesis

21 January 2018

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High frequency of RUNX1 biallelic alteration in acute myeloid leukemia secondary to familial platelet disorder.

21 January 2018

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Diagnostic criteria to distinguish hypocellular acute myeloid leukemia from hypocellular myelodysplastic syndromes and aplastic anemia: recommendations for a standardized approach

21 January 2018

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Inter-observer variance with the diagnosis of myelodysplastic syndromes (MDS) following the 2008 WHO classification.

21 January 2018

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Clinical and genetic characteristics of congenital sideroblastic anemia: comparison with myelodysplastic syndrome with ring sideroblast (MDS-RS).

21 January 2018

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Vitamin B(12)-responsive pancytopenia mimicking myelodysplastic syndrome

21 January 2018

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Severe vitamin B12 deficiency resulting in pancytopenia, splenomegaly and leukoerythroblastosis

21 January 2018

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Hematological manifestations of copper deficiency: a retrospective review

21 January 2018

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Assessment of dysplastic hematopoiesis: lessons from healthy bone marrow donors

21 January 2018

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Acute erythroid leukemia: a reassessment using criteria refined in the 2008 WHO classification

21 January 2018

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Proposals for the classification of the myelodysplastic syndromes

21 January 2018

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The World Health Organization (WHO) classification of the myeloid neoplasms

21 January 2018

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Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts

21 January 2018

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SF3B1 haploinsufficiency leads to formation of ring sideroblasts in myelodysplastic syndromes

21 January 2018

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Prognostic irrelevance of ring sideroblast percentage in World Health Organization-defined myelodysplastic syndromes without excess blasts.

21 January 2018

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Distinct haematological disorder with deletion of long arm of no. 5 chromosome

21 January 2018

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TP53 mutations in low-risk myelodysplastic syndromes with del(5q) predict disease progression.

21 January 2018

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Survival, prognostic factors and rates of leukemic transformation in 381 untreated patients with MDS and del(5q): a multicenter study.

21 January 2018

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Multi-color CD34⁺ progenitor-focused flow cytometric assay in evaluation of myelodysplastic syndromes in patients with post cancer therapy cytopenia

21 January 2018

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Serial assessment of suspected myelodysplastic syndromes: significance of flow cytometric findings validated by cytomorphology, cytogenetics, and molecular genetics

21 January 2018

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MDS-associated somatic mutations and clonal hematopoiesis are common in idiopathic cytopenias of undetermined significance

21 January 2018

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Revisiting guidelines for integration of flow cytometry results in the WHO classification of myelodysplastic syndromes-proposal from the International/European LeukemiaNet Working Group for Flow Cytometry in MDS.

21 January 2018

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New comprehensive cytogenetic scoring system for primary myelodysplastic syndromes (MDS) and oligoblastic acute myeloid leukemia after MDS derived from an international database merge

21 January 2018

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A compendium of cytogenetic abnormalities in myelofibrosis: molecular and phenotypic correlates in 826 patients

21 January 2018

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Clinical significance of Y chromosome loss in hematologic disease

21 January 2018

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Identification of RPS14 as a 5q- syndrome gene by RNA interference screen

21 January 2018

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Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype

21 January 2018

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Mutations in epigenetic modifiers in the pathogenesis and therapy of acute myeloid leukemia.

21 January 2018

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Prognostic significance of ASXL1 mutations in patients with myelodysplastic syndromes

21 January 2018

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Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

21 January 2018

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Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation

21 January 2018

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The oncogenic microRNA miR-22 targets the TET2 tumor suppressor to promote hematopoietic stem cell self-renewal and transformation

21 January 2018

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Additional prognostic value of bone marrow histology in patients subclassified according to the International Prognostic Scoring System for myelodysplastic syndromes.

21 January 2018

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Revised International Prognostic Scoring System (IPSS) predicts survival and leukemic evolution of myelodysplastic syndromes significantly better than IPSS and WHO Prognostic Scoring System: validation by the Gruppo Romano Mielodisplasie Italian Reg

21 January 2018

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Validation of the revised International Prognostic Scoring System in treated patients with myelodysplastic syndromes.

21 January 2018

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A prognostic score for patients with lower risk myelodysplastic syndrome

21 January 2018

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BCOR and BCORL1 mutations in myelodysplastic syndromes and related disorders.

21 January 2018

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Frequency and prognostic impact of mutations in SRSF2, U2AF1, and ZRSR2 in patients with myelodysplastic syndromes

21 January 2018

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Somatic mutations predict poor outcome in patients with myelodysplastic syndrome after hematopoietic stem-cell transplantation

21 January 2018

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Clinical use of erythropoietic stimulating agents in myelodysplastic syndromes.

21 January 2018

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Treatment of myelodysplastic syndrome patients with erythropoietin with or without granulocyte colony-stimulating factor: results of a prospective randomized phase 3 trial by the Eastern Cooperative Oncology Group (E1996).

21 January 2018

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A review of 76 patients with myelodysplastic syndromes treated with danazol

21 January 2018

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Current concepts in the pathophysiology and treatment of aplastic anemia

21 January 2018

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Factors affecting response and survival in patients with myelodysplasia treated with immunosuppressive therapy.

21 January 2018

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The clinical relevance of minor paroxysmal nocturnal hemoglobinuria clones in refractory cytopenia of childhood: a prospective study by EWOG-MDS.

21 January 2018

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Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS.

21 January 2018

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Lenalidomide in the myelodysplastic syndrome with chromosome 5q deletion

21 January 2018

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Prognostic impact of pre-transplantation transfusion history and secondary iron overload in patients with myelodysplastic syndrome undergoing allogeneic stem cell transplantation: a GITMO study

21 January 2018

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Myocardial iron loading by magnetic resonance imaging T2* in good prognostic myelodysplastic syndrome patients on long-term blood transfusions.

21 January 2018

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Results of a randomized, double-blind study of romiplostim versus placebo in patients with low/intermediate-1-risk myelodysplastic syndrome and thrombocytopenia

21 January 2018

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Rapid loss of response after withdrawal of treatment with azacitidine: a case series in patients with higher-risk myelodysplastic syndromes or chronic myelomonocytic leukemia.

21 January 2018

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Continued azacitidine therapy beyond time of first response improves quality of response in patients with higher-risk myelodysplastic syndromes

21 January 2018

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Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: a study of the cancer and leukemia group B.

21 January 2018

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Multicenter study of decitabine administered daily for 5 days every 4 weeks to adults with myelodysplastic syndromes: the alternative dosing for outpatient treatment (ADOPT) trial

21 January 2018

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Low-dose decitabine versus best supportive care in elderly patients with intermediate- or high-risk myelodysplastic syndrome (MDS) ineligible for intensive chemotherapy: final results of the randomized phase III study of the European Organisation fo

21 January 2018

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Phase 1/2 study of the combination of 5-aza-2'-deoxycytidine with valproic acid in patients with leukemia

21 January 2018

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Outcome of high-risk myelodysplastic syndrome after azacitidine treatment failure

21 January 2018

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A decision analysis of allogeneic bone marrow transplantation for the myelodysplastic syndromes: delayed transplantation for low-risk myelodysplasia is associated with improved outcome

21 January 2018

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Role of reduced-intensity conditioning allogeneic hematopoietic stem-cell transplantation in older patients with de novo myelodysplastic syndromes: an international collaborative decision analysis

21 January 2018

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Impact of adjunct cytogenetic abnormalities for prognostic stratification in patients with myelodysplastic syndrome and deletion 5q

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/AJH.24253

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26 July 2017

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