Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype (Q35011883)

5 August 2017

Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype (English)

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5 August 2017

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Ryan Morin

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Richard Humphries

object named as

R Keith Humphries

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author name string

Daniel T Starczynowski

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5 August 2017

Florian Kuchenbauer

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5 August 2017

Bob Argiropoulos

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5 August 2017

Sandy Sung

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5 August 2017

Andrew Muranyi

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5 August 2017

Martin Hirst

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5 August 2017

Donna Hogge

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5 August 2017

Marco Marra

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5 August 2017

Richard A Wells

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5 August 2017

Rena Buckstein

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5 August 2017

Wan Lam

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5 August 2017

Aly Karsan

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5 August 2017

language of work or name

English

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publication date

8 November 2009

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5 August 2017

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5 August 2017

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5 August 2017

49-58

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5 August 2017

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https://scigraph.springernature.com/pub.10.1038/nm.2054

5 August 2017

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cites work

Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin

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12 December 2020

MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia

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12 December 2020

NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses

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12 December 2020

Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation

1 reference

12 December 2020

Clinical management of myelodysplastic syndromes with interstitial deletion of chromosome 5q.

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12 December 2020

Simultaneous demonstration of clonal chromosome abnormalities and apoptosis in individual marrow cells in myelodysplastic syndrome

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12 December 2020

Isolation and characterization of hematopoietic progenitor/stem cells in 5q-deleted myelodysplastic syndromes: evidence for involvement at the hematopoietic stem cell level

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12 December 2020

Increased serum interleukin 6 levels in patients with myelodysplastic syndromes

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12 December 2020

Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88

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12 December 2020

Measurement of serum cytokine levels in patients with myelodysplastic syndromes

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12 December 2020

High-resolution whole genome tiling path array CGH analysis of CD34+ cells from patients with low-risk myelodysplastic syndromes reveals cryptic copy number alterations and predicts overall and leukemia-free survival.

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12 December 2020

MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells

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12 December 2020

TAK1 is required for the survival of hematopoietic cells and hepatocytes in mice

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12 December 2020

Stable knockdown of microRNA in vivo by lentiviral vectors

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12 December 2020

Chromosomal lesions and uniparental disomy detected by SNP arrays in MDS, MDS/MPD, and MDS-derived AML

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12 December 2020

Transplantable myeloproliferative disease induced in mice by an interleukin 6 retrovirus

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12 December 2020

Prediction of mammalian microRNA targets

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12 December 2020

MicroRNA expression profiling in relation to the genetic heterogeneity of acute myeloid leukemia

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12 December 2020

Interleukin-6: from basic science to medicine--40 years in immunology

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12 December 2020

HOXB4 overexpression mediates very rapid stem cell regeneration and competitive hematopoietic repopulation.

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12 December 2020

Circulating levels of thrombopoietic and inflammatory cytokines in patients with acute myeloblastic leukemia and myelodysplastic syndrome

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12 December 2020

Toll-like receptor-4 is up-regulated in hematopoietic progenitor cells and contributes to increased apoptosis in myelodysplastic syndromes

1 reference

12 December 2020

Genome-wide analysis of copy number changes and loss of heterozygosity in myelodysplastic syndrome with del(5q) using high-density single nucleotide polymorphism arrays

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12 December 2020

MicroRNA expression profiles of human leukemias

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12 December 2020

Engraftment of NOD/SCID-beta2 microglobulin null mice with multilineage neoplastic cells from patients with myelodysplastic syndrome

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12 December 2020

Myelodysplastic syndromes

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12 December 2020

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

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12 December 2020

Expression of microRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cells

1 reference

12 December 2020

MicroRNAs: genomics, biogenesis, mechanism, and function

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12 December 2020

Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment

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12 December 2020

Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha

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12 December 2020

Analysis of myelodysplastic syndromes with complex karyotypes by high-resolution comparative genomic hybridization and subtelomeric CGH array

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12 December 2020

Activation of vascular endothelial growth factor receptor-2 in bone marrow leads to accumulation of myeloid cells: role of granulocyte-macrophage colony-stimulating factor

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12 December 2020

Myelodysplastic syndromes: the complexity of stem-cell diseases

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12 December 2020

Mosaicism of the 5q deletion as assessed by interphase FISH is a common phenomenon in MDS and restricted to myeloid cells

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12 December 2020

Narrowing and genomic annotation of the commonly deleted region of the 5q- syndrome

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12 December 2020

Neutrophil dysplasia is not a specific feature of the abnormal chromosomal clone in myelodysplastic syndromes

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12 December 2020

MicroRNA expression in cytogenetically normal acute myeloid leukemia

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12 December 2020

Characterization of gene expression of CD34+ cells from normal and myelodysplastic bone marrow

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12 December 2020

Identification of RPS14 as a 5q- syndrome gene by RNA interference screen

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12 December 2020

Distinct microRNA expression profiles in acute myeloid leukemia with common translocations.

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12 December 2020

Mal interacts with tumor necrosis factor receptor-associated factor (TRAF)-6 to mediate NF-kappaB activation by toll-like receptor (TLR)-2 and TLR4.

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12 December 2020

Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice.

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12 December 2020

Multilineage involvement in the 5q- syndrome: a fluorescent in situ hybridization study on bone marrow smears

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12 December 2020

Biological and prognostic significance of chromosome 5q deletions in myeloid malignancies

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12 December 2020

Interference with nuclear factor kappa B and c-Jun NH2-terminal kinase signaling by TRAF6C small interfering RNA inhibits myeloma cell proliferation and enhances apoptosis

1 reference

12 December 2020

The molecular signature of MDS stem cells supports a stem-cell origin of 5q myelodysplastic syndromes

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12 December 2020

Identifiers

DOI

10.1038/NM.2054

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Dimensions Publication ID

5 August 2017

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