Accumulation of hypoxia-inducible factor-1alpha is limited by transcription-dependent depletion. (Q40421501)

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11 January 2020

title

Accumulation of hypoxia-inducible factor-1alpha is limited by transcription-dependent depletion (English)

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11 January 2020

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3

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11 January 2020

Paraskevi Giannakakou

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4

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11 January 2020

6

Mikhail V Blagosklonny

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11 January 2020

1

Zoya N Demidenko

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11 January 2020

author name string

AnnaMaria Rapisarda

series ordinal

2

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11 January 2020

Giovanni Melillo

series ordinal

5

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11 January 2020

language of work or name

English

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publication date

1 July 2005

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11 January 2020

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11 January 2020

volume

24

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11 January 2020

page(s)

4829-4838

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11 January 2020

issue

30

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1208636

11 January 2020

exact match

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cites work

Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor

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Regulation of HIF prolyl hydroxylases by hypoxia-inducible factors

21 January 2018

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HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

21 January 2018

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Do VHL and HIF-1 mirror p53 and Mdm-2? Degradation-transactivation loops of oncoproteins and tumor suppressors

21 January 2018

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Inhibition of HIF-1- and wild-type p53-stimulated transcription by codon Arg175 p53 mutants with selective loss of functions

21 January 2018

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Flavopiridol inactivates P-TEFb and blocks most RNA polymerase II transcription in vivo

21 January 2018

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Differential regulation of HIF-1 alpha prolyl-4-hydroxylase genes by hypoxia in human cardiovascular cells

21 January 2018

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Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation

21 January 2018

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Structural basis for inhibition of cyclin-dependent kinase 9 by flavopiridol

21 January 2018

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The von Hippel Lindau/hypoxia-inducible factor (HIF) pathway regulates the transcription of the HIF-proline hydroxylase genes in response to low oxygen

21 January 2018

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Flavopiridol induces p53 via initial inhibition of Mdm2 and p21 and, independently of p53, sensitizes apoptosis-reluctant cells to tumor necrosis factor

21 January 2018

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Hypoxia-inducible factor-1 (HIF-1) up-regulates adrenomedullin expression in human tumor cell lines during oxygen deprivation: a possible promotion mechanism of carcinogenesis.

21 January 2018

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HIF-1 as a target for drug development

21 January 2018

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The biology of hypoxia: the role of oxygen sensing in development, normal function, and disease

21 January 2018

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Mdm2 promotes the rapid degradation of p53

21 January 2018

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p73 and p63: why do we still need them?

21 January 2018

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Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway

21 January 2018

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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

21 January 2018

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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

21 January 2018

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Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation

21 January 2018

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Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes

21 January 2018

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Regulation of p53 stability by Mdm2

21 January 2018

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Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.

21 January 2018

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

21 January 2018

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Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing

21 January 2018

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Regulation of hypoxia-inducible factor-1alpha protein level during hypoxic conditions by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta pathway in HepG2 cells

21 January 2018

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HIF-1 and hypoxic response: the plot thickens.

21 January 2018

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Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: mechanism and therapeutic implications

21 January 2018

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The regulation of hypoxic genes by calcium involves c-Jun/AP-1, which cooperates with hypoxia-inducible factor 1 in response to hypoxia

21 January 2018

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HIF-1, O(2), and the 3 PHDs: how animal cells signal hypoxia to the nucleus

21 January 2018

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Targeting HIF-1 for cancer therapy

21 January 2018

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The forkhead transcription factor FOXO4 induces the down-regulation of hypoxia-inducible factor 1 alpha by a von Hippel-Lindau protein-independent mechanism

21 January 2018

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Hypoxia upregulates von Hippel-Lindau tumor-suppressor protein through RhoA-dependent activity in renal cell carcinoma

21 January 2018

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HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

21 January 2018

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Improving Cancer Therapy through p53 Management

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Transcription - guarding the genome by sensing DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208636

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1208636

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15897903%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

11 January 2020

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1 reference