Structural changes of region 1-16 of the Alzheimer disease amyloid beta-peptide upon zinc binding and in vitro aging (Q33227600)

24 July 2017

Structural changes of region 1-16 of the Alzheimer disease amyloid beta-peptide upon zinc binding and in vitro aging (English)

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24 July 2017

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Sylvie Rebuffat

8

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Sergey Kozin

object named as

Sergey A Kozin

2

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author name string

Séverine Zirah

1

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24 July 2017

Alexey K Mazur

3

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24 July 2017

Alain Blond

4

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24 July 2017

Michel Cheminant

5

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24 July 2017

Isabelle Ségalas-Milazzo

6

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24 July 2017

Pascale Debey

7

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24 July 2017

language of work or name

English

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publication date

21 November 2005

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Journal of Biological Chemistry

24 July 2017

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24 July 2017

281

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24 July 2017

4

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24 July 2017

2151-2161

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Solution Structures of β Peptide and Its Constituent Fragments: Relation to Amyloid Deposition

24 July 2017

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NMR studies of amyloid beta-peptides: proton assignments, secondary structure, and mechanism of an alpha-helix----beta-sheet conversion for a homologous, 28-residue, N-terminal fragment

21 January 2018

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Solution structure of residues 1-28 of the amyloid beta-peptide

21 January 2018

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1H NMR of A beta amyloid peptide congeners in water solution. Conformational changes correlate with plaque competence

21 January 2018

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Structure of amyloid A4-(1-40)-peptide of Alzheimer's disease

21 January 2018

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Solution structure of amyloid beta-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is?

21 January 2018

1 reference

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Solution structures of micelle-bound amyloid beta-(1-40) and beta-(1-42) peptides of Alzheimer's disease

21 January 2018

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The Alzheimer's peptide a beta adopts a collapsed coil structure in water

21 January 2018

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In situ characterization of beta-amyloid in Alzheimer's diseased tissue by synchrotron Fourier transform infrared microspectroscopy

21 January 2018

1 reference

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Structural analysis of Alzheimer's beta(1-40) amyloid: protofilament assembly of tubular fibrils.

21 January 2018

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Medicine: danger--misfolding proteins.

21 January 2018

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A structural model for Alzheimer's beta -amyloid fibrils based on experimental constraints from solid state NMR

21 January 2018

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Therapeutically effective antibodies against amyloid-beta peptide target amyloid-beta residues 4-10 and inhibit cytotoxicity and fibrillogenesis.

21 January 2018

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N-terminal EFRH sequence of Alzheimer's beta-amyloid peptide represents the epitope of its anti-aggregating antibodies

21 January 2018

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The metallobiology of Alzheimer's disease

21 January 2018

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Aluminum, iron, and zinc ions promote aggregation of physiological concentrations of beta-amyloid peptide.

21 January 2018

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Rapid induction of Alzheimer A beta amyloid formation by zinc.

21 January 2018

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Copper, iron and zinc in Alzheimer's disease senile plaques.

21 January 2018

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Histochemically-reactive zinc in amyloid plaques, angiopathy, and degenerating neurons of Alzheimer's diseased brains

21 January 2018

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New insights on how metals disrupt amyloid beta-aggregation and their effects on amyloid-beta cytotoxicity

21 January 2018

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Imaging real-time aggregation of amyloid beta protein (1-42) by atomic force microscopy.

21 January 2018

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Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits

21 January 2018

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Metals, toxicity and oxidative stress

21 January 2018

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Metal binding modes of Alzheimer's amyloid beta-peptide in insoluble aggregates and soluble complexes.

21 January 2018

1 reference

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Characterization of the ZnII binding to the peptide amyloid-beta1-16 linked to Alzheimer's disease.

21 January 2018

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Irreversible dimerization/tetramerization and post-translational modifications inhibit proteolytic degradation of A beta peptides of Alzheimer's disease.

21 January 2018

1 reference

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The presence of isoaspartic acid in beta-amyloid plaques indicates plaque age.

21 January 2018

1 reference

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Reduction of beta-amyloid plaques in brain of transgenic mouse model of Alzheimer's disease by EFRH-phage immunization

21 January 2018

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Efficacy of anti-Abeta antibody isotypes used for intracerebroventricular immunization in TgCRND8.

21 January 2018

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Zinc binding agonist effect on the recognition of the beta-amyloid (4-10) epitope by anti-beta-amyloid antibodies

21 January 2018

1 reference

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The chemical shift index: a fast and simple method for the assignment of protein secondary structure through NMR spectroscopy

21 January 2018

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Relationship between electrostatics and redox function in human thioredoxin: characterization of pH titration shifts using two-dimensional homo- and heteronuclear NMR.

21 January 2018

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Characterization of pKa values and titration shifts in the cytotoxic ribonuclease alpha-sarcin by NMR. Relationship between electrostatic interactions, structure, and catalytic function.

21 January 2018

1 reference

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Calibration of the angular dependence of the amide proton-C alpha proton coupling constants, 3JHN alpha, in a globular protein. Use of 3JHN alpha for identification of helical secondary structure

21 January 2018

1 reference

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Calculation of protein conformations by proton-proton distance constraints. A new efficient algorithm

21 January 2018

1 reference

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Determination of three-dimensional structures of proteins by simulated annealing with interproton distance restraints. Application to crambin, potato carboxypeptidase inhibitor and barley serine proteinase inhibitor 2.

21 January 2018

1 reference

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CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

21 January 2018

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A Second Generation Force Field for the Simulation of Proteins, Nucleic Acids, and Organic Molecules

21 January 2018

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MOLMOL: a program for display and analysis of macromolecular structures

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Recent changes to RasMol, recombining the variants

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PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

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Sequencing of peptides and proteins with blocked N-terminal amino acids: N-acetylserine or N-acetylthreonine

21 January 2018

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Identification of an isoaspartyl linkage formed upon deamidation of bovine calbindin D9k and structural characterization by 2D 1H NMR.

21 January 2018

1 reference

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Zinc-induced Alzheimer's Abeta1-40 aggregation is mediated by conformational factors.

21 January 2018

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Solution NMR studies of the A beta(1-40) and A beta(1-42) peptides establish that the Met35 oxidation state affects the mechanism of amyloid formation

21 January 2018

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Isoaspartate formation and neurodegeneration in Alzheimer's disease

21 January 2018

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Amino- and carboxyl-terminal heterogeneity of beta-amyloid peptides deposited in human brain.

21 January 2018

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Zinc Binding to Alzheimer's Aβ(1–16) Peptide Results in Stable Soluble Complex

21 January 2018

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Zinc binding properties of the amyloid fragment Aβ(1–16) studied by electrospray-ionization mass spectrometry

21 January 2018

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Immunotherapy for Alzheimer's disease

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[34] X-Ray fiber diffraction of amyloid fibrils

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M504454200

1 reference

24 July 2017

1 reference