Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles (Q32173000)

6 July 2017

Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles (English)

1 reference

6 July 2017

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29

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Nicolas Stransky

14

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Chandra Sekhar Pedamallu

19

Chandra Sekhar Pedamallu

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Nabeel Bardeesy

42

Nabeel Bardeesy

1 reference

6 July 2017

Suhn K Rhie

23

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Jason Roszik

Jason Roszik

10

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Jesper B. Andersen

Jesper B Andersen

41

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Lewis R. Roberts

Lewis R Roberts

43

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Michael S. Torbenson

35

Michael S Torbenson

1 reference

6 July 2017

36

David E Kleiner

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6 July 2017

31

Andrew D Cherniack

1 reference

6 July 2017

8

Katherine A Hoadley

1 reference

6 July 2017

Farshad Farshidfar

1

1 reference

6 July 2017

Siyuan Zheng

2

1 reference

6 July 2017

Marie-Claude Gingras

3

1 reference

6 July 2017

Yulia Newton

4

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6 July 2017

Juliann Shih

5

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6 July 2017

A Gordon Robertson

6

1 reference

6 July 2017

Toshinori Hinoue

7

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6 July 2017

Ewan A Gibb

9

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6 July 2017

Kyle R Covington

11

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6 July 2017

Chia-Chin Wu

12

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6 July 2017

Eve Shinbrot

13

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6 July 2017

Apurva Hegde

15

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6 July 2017

Ju Dong Yang

16

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6 July 2017

Ed Reznik

17

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6 July 2017

Sara Sadeghi

18

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6 July 2017

Akinyemi I Ojesina

20

1 reference

6 July 2017

Julian M Hess

21

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6 July 2017

J Todd Auman

22

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6 July 2017

Reanne Bowlby

24

1 reference

6 July 2017

Mitesh J Borad

25

1 reference

6 July 2017

Cancer Genome Atlas Network

26

1 reference

6 July 2017

Andrew X Zhu

27

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6 July 2017

Josh M Stuart

28

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6 July 2017

Rehan Akbani

30

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6 July 2017

Vikram Deshpande

32

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6 July 2017

Taofic Mounajjed

33

1 reference

6 July 2017

Wai Chin Foo

34

1 reference

6 July 2017

Peter W Laird

37

1 reference

6 July 2017

David A Wheeler

38

1 reference

6 July 2017

Autumn J McRee

39

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6 July 2017

Oliver F Bathe

40

1 reference

6 July 2017

Lawrence N Kwong

44

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6 July 2017

1 March 2017

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6 July 2017

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6 July 2017

18

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6 July 2017

2780-2794

1 reference

6 July 2017

11

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Polyclonal Secondary FGFR2 Mutations Drive Acquired Resistance to FGFR Inhibition in Patients with FGFR2 Fusion-Positive Cholangiocarcinoma

6 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Forty-Year Trends in Cholangiocarcinoma Incidence in the U.S.: Intrahepatic Disease on the Rise

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Mitochondrial DNA copy number variation across human cancers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Extreme Vulnerability of IDH1 Mutant Cancers to NAD+ Depletion.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

SWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZH2

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Functional and genetic deconstruction of the cellular origin in liver cancer.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Loss of BAP1 function leads to EZH2-dependent transformation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Difficult Diagnostic Problems in Pancreatobiliary Neoplasia.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Oncometabolic mutation IDH1 R132H confers a metformin-hypersensitive phenotype.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Metabolic consequences of oncogenic IDH mutations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Massive parallel sequencing uncovers actionable FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Mutation profiling in cholangiocarcinoma: prognostic and therapeutic implications

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Mutational landscape of intrahepatic cholangiocarcinoma.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

The somatic genomic landscape of chromophobe renal cell carcinoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Cancer of unknown primary site.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

IDH1 mutations alter citric acid cycle metabolism and increase dependence on oxidative mitochondrial metabolism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

New routes to targeted therapy of intrahepatic cholangiocarcinomas revealed by next-generation sequencing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Integrated genomic characterization reveals novel, therapeutically relevant drug targets in FGFR and EGFR pathways in sporadic intrahepatic cholangiocarcinoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Morphological subclassification of intrahepatic cholangiocarcinoma: etiological, clinicopathological, and molecular features

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Fibroblast growth factor receptor 2 tyrosine kinase fusions define a unique molecular subtype of cholangiocarcinoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Mutational heterogeneity in cancer and the search for new cancer-associated genes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

A tale of metabolites: the cross-talk between chromatin and energy metabolism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Modeling pathogenesis of primary liver cancer in lineage-specific mouse cell types.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Cholangiocarcinomas can originate from hepatocytes in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Transcriptomic profiling reveals hepatic stem-like gene signatures and interplay of miR-200c and epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Cancer-associated isocitrate dehydrogenase mutations inactivate NADPH-dependent reductive carboxylation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Are common factors involved in the pathogenesis of primary liver cancers? A meta-analysis of risk factors for intrahepatic cholangiocarcinoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Frequent mutation of isocitrate dehydrogenase (IDH)1 and IDH2 in cholangiocarcinoma identified through broad-based tumor genotyping

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Genomic and genetic characterization of cholangiocarcinoma identifies therapeutic targets for tyrosine kinase inhibitors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

miR-194 is a marker of hepatic epithelial cells and suppresses metastasis of liver cancer cells in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Identification of a cholangiocarcinoma-like gene expression trait in hepatocellular carcinoma.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Cisplatin plus gemcitabine versus gemcitabine for biliary tract cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Cholangiocarcinoma Heterogeneity Revealed by Multigene Mutational Profiling: Clinical and Prognostic Relevance in Surgically Resected Patients.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Genomic spectra of biliary tract cancer.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Biliary Tract Cancers: Finding Better Ways to Lump and Split

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Exome sequencing identifies distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Isocitrate dehydrogenase 1 and 2 mutations in cholangiocarcinoma.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

A fibrous stromal component in hepatocellular carcinoma reveals a cholangiocarcinoma-like gene expression trait and epithelial-mesenchymal transition.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5493145

Intrahepatic cholangiocarcinoma with predominant "ductal plate malformation" pattern: a new subtype

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28297679

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Exome sequencing of liver fluke-associated cholangiocarcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28297679

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The Genotype-Tissue Expression (GTEx) project

1 reference

31 March 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELREP.2017.02.033

Identifiers

DOI

10.1016/J.CELREP.2017.02.033

1 reference

6 July 2017

1 reference

6 July 2017

1 reference