A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation (Q31814841)

4 July 2017

A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation (English)

1 reference

4 July 2017

BLM RecQ like helicase

1 reference

protein homooligomerization

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Stephane Rety

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28228481%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Jing Shi

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28228481%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Wei-Fei Chen

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28228481%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Bo Zhang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28228481%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

San-Hong Fan

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28228481%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Xia Ai

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28228481%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Na-Nv Liu

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28228481%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Xu-Guang Xi

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28228481%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

language of work or name

English

0 references

publication date

22 February 2017

1 reference

Journal of Biological Chemistry

4 July 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28228481%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

292

1 reference

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13 June 2020

issue

14

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13 June 2020

page(s)

5909-5920

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Structure and mechanism of helicases and nucleic acid translocases

13 June 2020

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RecQ helicases; at the crossroad of genome replication, repair, and recombination

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Probing the structural basis of RecQ helicase function

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High-resolution structure of the E.coli RecQ helicase catalytic core

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Structural mechanisms of human RecQ helicases WRN and BLM.

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Disease-causing missense mutations in human DNA helicase disorders

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A novel frameshift mutation in BLM gene associated with high sister chromatid exchanges (SCE) in heterozygous family members.

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Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA

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Endogenous gamma-H2AX-ATM-Chk2 checkpoint activation in Bloom's syndrome helicase deficient cells is related to DNA replication arrested forks

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Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest

21 January 2018

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Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair

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BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair

21 January 2018

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The Bloom's syndrome gene product interacts with topoisomerase III

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The role of post-translational modifications in fine-tuning BLM helicase function during DNA repair

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Insights into the evolution of the nucleolus by an analysis of its protein domain repertoire

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Structural classification of HTH DNA-binding domains and protein-DNA interaction modes

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EF-hand calcium-binding proteins.

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The C2 domain of SynGAP is essential for stimulation of the Rap GTPase reaction

21 January 2018

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Visualization of human Bloom's syndrome helicase molecules bound to homologous recombination intermediates

21 January 2018

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Multimeric BLM is dissociated upon ATP hydrolysis and functions as monomers in resolving DNA structures

21 January 2018

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Analysis of the unwinding activity of the dimeric RECQ1 helicase in the presence of human replication protein A

21 January 2018

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Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stability

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Human RecQ helicases in DNA repair, recombination, and replication.

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Phosphorylation of BLM, dissociation from topoisomerase IIIalpha, and colocalization with gamma-H2AX after topoisomerase I-induced replication damage

21 January 2018

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Intra-nuclear trafficking of the BLM helicase to DNA damage-induced foci is regulated by SUMO modification

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Oligomeric ring structure of the Bloom's syndrome helicase

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Different quaternary structures of human RECQ1 are associated with its dual enzymatic activity

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Human RECQ1 helicase-driven DNA unwinding, annealing, and branch migration: insights from DNA complex structures

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Biochemical and kinetic characterization of the DNA helicase and exonuclease activities of werner syndrome protein

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12 December 2020

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Identifiers

DOI

10.1074/JBC.M116.761510

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28228481%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28228481%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference