The C2 domain of SynGAP is essential for stimulation of the Rap GTPase reaction (Q27650014)

6

0 references

Mohammad Reza Ahmadian

8

0 references

Klaus Scheffzek

9

0 references

Michael Hothorn

2

0 references

author name string

Vladimir Pena

1

0 references

Alexander Eberth

3

0 references

Nikolai Kaschau

4

0 references

Annabel Parret

5

0 references

Fabien Bonneau

SynGAP regulates synaptic strength and mitogen-activated protein kinases in cultured neurons

7

0 references

publication date

April 2008

0 references

published in

EMBO Reports

0 references

volume

9

0 references

page(s)

350-5

0 references

issue

4

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

The GTPase-activating protein Rap1GAP uses a catalytic asparagine

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

A novel human RasGAP-like gene that maps within the prostate cancer susceptibility locus at chromosome 1q25

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

The C2 domain calcium-binding motif: structural and functional diversity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

Crystal structure of the GTPase-activating domain of human p120GAP and implications for the interaction with Ras

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

Identification of a specific Ins(1,3,4,5)P4-binding protein as a member of the GAP1 family

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

The guanine nucleotide-binding switch in three dimensions

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

The role of synaptic GTPase-activating protein in neuronal development and synaptic plasticity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

Signal-processing machines at the postsynaptic density

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

SynGAP regulates spine formation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

SynGAP-MUPP1-CaMKII synaptic complexes regulate p38 MAP kinase activity and NMDA receptor-dependent synaptic AMPA receptor potentiation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

Regulation of the neuron-specific Ras GTPase-activating protein, synGAP, by Ca2+/calmodulin-dependent protein kinase II

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

A synaptic Ras-GTPase activating protein (p135 SynGAP) inhibited by CaM kinase II

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

SynGAP: a synaptic RasGAP that associates with the PSD-95/SAP90 protein family

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

A role for synGAP in regulating neuronal apoptosis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

SynGAP regulates ERK/MAPK signaling, synaptic plasticity, and learning in the complex with postsynaptic density 95 and NMDA receptor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

Confirmation of the arginine-finger hypothesis for the GAP-stimulated GTP-hydrolysis reaction of Ras

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

20 March 2017

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FEMBOR.2008.20

C2-domains, structure and function of a universal Ca2+-binding domain

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

GTPase activating proteins: structural and functional insights 18 years after discovery

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

The C2 domain of PKCdelta is a phosphotyrosine binding domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

Pleckstrin homology domains: not just for phosphoinositides

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

GAPs galore! A survey of putative Ras superfamily GTPase activating proteins in man and Drosophila

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

Ras and Rap control AMPA receptor trafficking during synaptic plasticity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

Membrane targeting by C1 and C2 domains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

The Ras branch of small GTPases: Ras family members don't fall far from the tree

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

Selective disactivation of neurofibromin GAP activity in neurofibromatosis type 1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

GAP1 family members constitute bifunctional Ras and Rap GTPase-activating proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

Expression of p21 proteins in Escherichia coli and stereochemistry of the nucleotide-binding site

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

Inhibition of GTPase activating protein stimulation of Ras-p21 GTPase by the Krev-1 gene product

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288765

Rap-specific GTPase activating protein follows an alternative mechanism

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FEMBOR.2008.20

Monitoring the real-time kinetics of the hydrolysis reaction of guanine nucleotide-binding proteins

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FEMBOR.2008.20

Amino acid 61 is a determinant of sensitivity of rap proteins to the ras GTPase activating protein

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18323856

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/EMBOR.2008.20

0 references

Fatcat ID

release_u5ugfrexkfe6jdqdhfap7l6co4

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/u5ugfrexkfe6jdqdhfap7l6co4